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The Neuronal Pathways forming Synapses on Outer Stellate, Basket and Golgi Cells

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The Cerebellum as a Neuronal Machine

Abstract

It is convenient to consider these cells before the Purkinje cells, because the first two types exert a powerful inhibitory influence on Purkinje cells (Andersen, Eccles and Voorhoeve, 1964; Eccles, Llinas and Sasaki, 1966 b, 1966 e; Eccles, Sasaki and Strata, 1966, 1967b). The general structural features of these three types of interneurones have been described in Chapter I. Since these interneurones are all excited by the same presynaptic channels, the parallel fibers and to a very much less extent the climbing fibers, they will be considered together. Firstly, there will be an account of the presynaptic pathways, then of the responses generated thereby.

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References

  • Andersen, P., and P. E. Voorhoeve: Postsynaptic inhibition of cerebellar Purkinje cells. J. Neurophysiol. 27, 1138–1153 (1964).[55, 58, 63, 64, 68, 82, 84, 85, 86, 91, 93, 102, 146, 187, 189]

    PubMed  CAS  Google Scholar 

  • Eccles, J. C., R. LI.INns, and K. Sasaki: Parallel fiber stimulation and the responses induced thereby in the Purkinje cells of the cerebellum. Exp. Brain Res. 1, 17–39 (1966b).[54–58, 63, 64, 81, 83, 86, 91, 93, 100–102, 104, 107, 109, 187]

    CAS  Google Scholar 

  • Eccles, J. C., R. LI.INns, The action of antidromic impulses on the cerebellar Purkinje cells. J. Physiol. (Lond.) 182, 316–345 (1966 e).[58, 63, 64, 65, 68, 70, 72, 74, 75, 76, 77, 78, 79, 82, 84, 87, 89, 90, 91, 93, 102, 105, 106, 108, 109, 144, 149, 176, 184, 185, 187, 188]

    Google Scholar 

  • Eccles, J. C., K. Sasaki, and P. Strata: The profiles of physiological events produced by a parallel fiber volley in the cerebellar cortex. Exp. Brain Res. 2, 18–34 (1966).[58, 63, 64, 72, 82, 86, 93, 100, 102, 103, 104, 106, 112, 113, 115, 153]

    CAS  Google Scholar 

  • Eccles, J. C., K. Sasaki, A comparison of the inhibitory actions of Golgi cells and of basket cells. Exp. Brain Res. 3, 81–94 (1967b).[58, 82, 91, 116, 149, 151, 152, 153, 191, 220]

    Google Scholar 

  • Hamori, J., Identification under the electron microscope of climbing fibers and their synaptic contacts. Exp. Brain Res. 1, 65–81 (1966a).[30, 32, 38, 40, 41, 58, 59, 60, 61, 98, 99, 142, 156, 182, 225]

    CAS  Google Scholar 

  • Scheibel, M. E., and A. B. Scheibel: Observations on the intracortical relations of the climbing fibers of the cerebellum. J. comp. Neurol. 101, 733–760 (1954).[30, 32, 36, 37, 38, 39, 58, 60, 61, 68, 156, 181, 225]

    Article  PubMed  CAS  Google Scholar 

  • Hamori, J., Identification under the electron microscope of climbing fibers and their synaptic contacts. Exp. Brain Res. 1, 65–81 (1966a).[30, 32, 38, 40, 41, 58, 59, 60, 61, 98, 99, 142, 156, 182, 225]

    CAS  Google Scholar 

  • Hamori, J., Identification under the electron microscope of climbing fibers and their synaptic contacts. Exp. Brain Res. 1, 65–81 (1966a).[30, 32, 38, 40, 41, 58, 59, 60, 61, 98, 99, 142, 156, 182, 225]

    CAS  Google Scholar 

  • Jakob, A.: Das Kleinhirn. In: Handbuch der mikroskopischen Anatomie des Menschen, vol. 4, pp. 674–916. Ed. W. v. MÖLlendorff. Berlin: Springer 1928.[27, 60, 99, 229, 242]

    Google Scholar 

  • Jansen, J., Das Kleinhirn. In: Handbuch der mikroskopischen Anatomie des Menschen, vol. 4/8 Nervensystem, pp. 1–323. Ed. W. v. MÖLlendorff and W. Bargmann. Berlin-Göttingen-Heidelberg: Springer 1958.[1, 33, 34, 60, 227, 234, 262, 264, 304]

    Google Scholar 

  • RamÔN Y Cajal, S.: Histologie du Système Nerveux de L’Homme et des Vertébrés. Tome II. 993 pp. Paris: Maloine 1911.[1, 11, 13, 22, 26, 27, 28, 32, 36, 37, 43, 45, 60, 61, 69, 107, 113, 118, 119, 123, 165, 178, 182, 196, 198, 215, 225, 229, 232, 262, 263, 267]

    Google Scholar 

  • Scheibel, M. E., and A. B. Scheibel: Observations on the intracortical relations of the climbing fibers of the cerebellum. J. comp. Neurol. 101, 733–760 (1954).[30, 32, 36, 37, 38, 39, 58, 60, 61, 68, 156, 181, 225]

    Article  PubMed  CAS  Google Scholar 

  • Hamori, J., Identification under the electron microscope of climbing fibers and their synaptic contacts. Exp. Brain Res. 1, 65–81 (1966a).[30, 32, 38, 40, 41, 58, 59, 60, 61, 98, 99, 142, 156, 182, 225]

    CAS  Google Scholar 

  • Hamori, J., Participation of Golgi neurone processes in the cerebellar glomeruli: An electron microscope study. Exp. Brain Res. 2, 35–48 (1966b).[24, 61, 68, 123, 125, 127, 136, 142, 153, 220, 221]

    CAS  Google Scholar 

  • RamÔN Y Cajal, S.: Histologie du Système Nerveux de L’Homme et des Vertébrés. Tome II. 993 pp. Paris: Maloine 1911.[1, 11, 13, 22, 26, 27, 28, 32, 36, 37, 43, 45, 60, 61, 69, 107, 113, 118, 119, 123, 165, 178, 182, 196, 198, 215, 225, 229, 232, 262, 263, 267]

    Google Scholar 

  • Scheibel, M. E., and A. B. Scheibel: Observations on the intracortical relations of the climbing fibers of the cerebellum. J. comp. Neurol. 101, 733–760 (1954).[30, 32, 36, 37, 38, 39, 58, 60, 61, 68, 156, 181, 225]

    Article  PubMed  CAS  Google Scholar 

  • Szentagothai, J., K. Rajkovits: Über den Ursprung der Kletterfasern des Kleinhirns. Z. Anat. Entwickl.-Gesch. 121, 130–141 (1959).[37, 38, 39, 61, 68, 156, 165, 181, 305]

    Article  Google Scholar 

  • Eccles, J. C., R. LI.INns, Intracellularly recorded responses of the cerebellar Purkinje cells. Exp. Brain Res. 1, 161–183 (1966 f).[63, 81, 83, 85, 91, 146, 148, 187, 188, 192, 193, 217, 225]

    Google Scholar 

  • Eccles, J. C., R. LI.INns, The excitatory synaptic action of climbing fibers on the Purkinje cells of the cerebellum. J. Physiol. (Lond.) 182, 268–296 (1966 d).[65, 68, 80, 83, 93, 156, 157, 159, 160, 161, 162, 163, 174, 225, 239, 256, 259, 283, 305, 309]

    Google Scholar 

  • Granit, R., and C. G. Phillips: Excitatory and inhibitory processes acting upon individual Purkinje cells of the cerebellum in cats. J. Physiol. (Lond.) 133, 520–547 (1956).[65, 71, 147, 158, 165, 166, 169, 171, 188, 190, 191, 306]

    Google Scholar 

  • Eccles, J. C., K. Sasaki, The potential fields generated in the cerebellar cortex by a mossy fiber volley. Exp. Brain Res. 3, 58–80 (1967a).[69, 74, 80, 116, 130, 131, 132, 137, 138, 141, 143, 145, 153, 154, 155, 187, 191]

    Google Scholar 

  • Fox, C. A., K. A. Siegesmund, and C. R. Dutta: The Purkinje cell dendritic branchlets and their relation with the parallel fibers: Light and electron microscopic observations. In: Morphological and Biochemical Correlates of Neural Activity, pp. 112–141. Ed. M. M. Cohen and R. S. Snider. New York Harper and Row 1964.[13, 45, 49, 55, 69, 70, 178, 202]

    Google Scholar 

  • Gray, E. G.: The granule cells, mossy synapses and Purkinje spine synapses of the cerebellum: Light and electron microscope observations. J. Anat. (Lond.) 95, 345–356 (1961).[32, 45, 69, 119, 125, 128, 133]

    CAS  Google Scholar 

  • Hamori, J., and J. Szentagothai: The “Crossing Over” synapse. An electron microscope study of the molecular layer in the cerebellar cortex. Acta biol. Acad. Sci. hung. 15, 95–117 (1964).[15, 45, 47–50, 52, 53, 55, 69, 204, 314]

    Article  Google Scholar 

  • Eccles, J. C.: The Physiology of Synapses. 316 pp. Berlin-Göttingen-Heidelberg: Springer 1964.[70, 72, 109, 111, 136, 171, 174, 235, 243, 245, 289]

    Book  Google Scholar 

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Eccles, J.C., Ito, M., Szentágothai, J. (1967). The Neuronal Pathways forming Synapses on Outer Stellate, Basket and Golgi Cells. In: The Cerebellum as a Neuronal Machine. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-662-13147-3_5

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  • DOI: https://doi.org/10.1007/978-3-662-13147-3_5

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-662-13149-7

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