Abstract
A series of studies based on ambulatory ECG and arterial pressure monitoring in patients with chronic stable, predominantly effort-related angina and severe coronary artery disease have shown that the majority of ischemic events which occur during normal unrestricted daily activity, are not preceded by an increase in the major determinants of myocardial oxygen consumption (1–4). They occur at levels of heart rate or rate-pressure product well below those observed at the beginning of exercise-induced ST-segment depression. These findings imply that in these patients, ischemia is often the consequence of transient active impairment of regional myocardial perfusion, rather than of an increase in myocardial oxygen demand exceeding the residual coronary flow reserve.
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References
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© 1987 Springer-Verlag Berlin Heidelberg
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Chierchia, S. (1987). Alpha-receptors and transient ischemia. In: v. Arnim, T., Maseri, A. (eds) Silent Ischemia. Steinkopff, Heidelberg. https://doi.org/10.1007/978-3-662-12997-5_4
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DOI: https://doi.org/10.1007/978-3-662-12997-5_4
Publisher Name: Steinkopff, Heidelberg
Print ISBN: 978-3-662-12999-9
Online ISBN: 978-3-662-12997-5
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