Physical Characterization of the Protein Molecule

  • Ken E. van Holde
Part of the Molecular Biology Biochemistry and Biophysics / Molekularbiologie Biochemie und Biophysik book series (MOLECULAR, volume 8)


Expending research effort on impure materials is a gross waste of time and talent. Yet there always exists the danger that a protein chemist, working with materials that are intrinsically hard to purify, may carry out detailed chemical studies with contaminated samples. It is the purpose of this chapter to outline some techniques by which at least the physical homogeneity of a protein may be judged. Such studies are a necessary prelude to detailed chemical investigations of proteins.


Sedimentation Velocity Physical Characterization Guanidine Hydrochloride Number Average Molecular Weight Sedimentation Coefficient 
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© Springer-Verlag Berlin Heidelberg 1970

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  • Ken E. van Holde

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