The Clinical and Prognostic Relevance of Histopathologic Classification in Hodgkin’s Disease

  • Michael H. Bennett
  • Kenneth A. MacLennan
  • Bryan Vaughan Hudson
  • Gillian Vaughan Hudson


Few diseases have caused such confusion or generated as much controversy as Hodgkin’s disease. The debate over this disease has centered not only on terminology (by 1933 Wallhauser1 could find 52 synonyms for this condition in the literature), but also upon the basic nature of the disease process. The view that Hodgkin’s disease was inflammatory was held by many workers. Some believed it was an atypical reaction to the Tubercle bacillus,2 others were convinced it was a malignant tumor.3, 4 Modern karyotypic and culture studies have confirmed Hodgkin’s disease to be a neoplastic process,5,9 but although many theories have been proposed,6, 9,1016 the precise identity of the malignant cell has remained obscure.


Actuarial Survival Diffuse Fibrosis Mixed Cellularity Lacunar Cell Cellular Nodule 
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Copyright information

© Springer-Verlag Berlin Heidelberg 1989

Authors and Affiliations

  • Michael H. Bennett
  • Kenneth A. MacLennan
  • Bryan Vaughan Hudson
  • Gillian Vaughan Hudson

There are no affiliations available

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