Abstract
LUNG CARCINOMAS ARE CLASSIFIED according to the traditional categories of squamous carcinoma, adenocarcinoma, small cell carcinoma, and large cell undifferentiated carcinoma; significant therapeutic decisions depend on the specific histologic category into which a tumor is placed.1,2 Small cell carcinoma, in particular, is regarded as a unique clinical-pathologic entity. From both a morphologic and functional standpoint, small cell carcinomas exhibit neuroendocrine (APUD) differentiation. From a clinical standpoint, a typically aggressive clinical course and sensitivity to radiation and chemotherapy have distinguished small cell carcinomas from other histologic types of lung carcinoma.3,4
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Mendelsohn, G., Suarez, M., Hassan, M.O., Subramanyan, S., Maksem, J.A. (1986). Histopathologic, Immunohistochemical, and Ultrastructural Studies of Lung Carcinomas. In: Fenoglio-Preiser, C.M., Wolff, M., Rilke, F. (eds) Progress in Surgical Pathology. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-662-12817-6_5
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DOI: https://doi.org/10.1007/978-3-662-12817-6_5
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