Bioassay and Characterization of Crustacean Limb Growth-Controlling Factors

  • Dorothy E. Bliss
  • Penny M. Hopkins


For close to 70 years, biologists have known that removal of eyestalks from a decapod crustacean induces molting and precocious ecdysis (Zeleny, 1905; Megušar, 1912). For almost half that time, they have known that reimplantation of eyestalks reverses this effect (Brown and Cunningham, 1939; Scudamore, 1947). Accordingly, they have postulated the existence of a crustacean molt-inhibiting hormone (MIH). In 1953, the work of Passano (1953) implicated neurosecretory cells in the x organs of the eyestalks as a major source of MIH.


Limb Regeneration Decapod Crustacean Perfusion Fluid Sinus Gland Land Crab 
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Copyright information

© Springer-Verlag Berlin Heidelberg 1974

Authors and Affiliations

  • Dorothy E. Bliss
    • 1
  • Penny M. Hopkins
    • 1
  1. 1.Department of Living InvertebratesThe American Museum of Natural HistoryNew YorkUSA

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