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Erkrankungen von Knochen, Muskeln und Gelenken

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Medizinische Therapie in Klinik und Praxis

Zusammenfassung

Unter dem Überbegriff Osteopathien werden verschiedene Knochenerkrankungen zusammengefasst. Man differenziert die metabolischen Osteopathien von zirkulatorischen Störungen (Osteonekrosen) und toxischen, infektiösen sowie neoplastischen Osteopathien. Zu den metabolischen Osteopathien wird eine Reihe von Krankheiten gezählt, deren Ursachen sehr unterschiedlich sind, z. B. Hyper- und Hypoparathyreoidismus. Im nachfolgenden Kapitel wird vor allem auf Osteoporose und Osteomalazie eingegangen, der M. Paget ist in Kap. 7.2 ausführlich dargestellt.

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Literatur

  • Bilezikian JP, Raisz LG, Rhodan GA (1996) Principles of bone biology. Academic Press, San Diego London Boston New York Sydney Tokyo Toronto

    Google Scholar 

  • Consensus Development Statement (1997) Who are candidates for prevention and treatment for osteoporosis? Osteoporosis Int 7: 1–6

    Google Scholar 

  • Dambacher MA, Neff M (2001) Erworbene Skelettsystemerkrankungen. In: Wirth CJ (Hrsg) Praxis der Orthopädie. Thieme, Stuttgart New York, S 371–414

    Google Scholar 

  • Ettinger B, Black DM, Mitlak BH et al. (1999) Reduction of vertebral fracture risk in postmenopausal women with osteoporosis treated with raloxifene. JAMA 282: 637–645

    Article  PubMed  CAS  Google Scholar 

  • Marshall D, Johnell O, Wedel H (1996) Meta-analysis of how well measures of bone mineral density predict occurence of osteoporotic fractures. BMJ 12: 1254–1259

    Article  Google Scholar 

  • McClung MR, Geusens P, Miller PD et al. (2001) Effect of risedronate on the risk of hip fracture in elderly women. N Engl J Med 344: 333–340

    Article  PubMed  CAS  Google Scholar 

  • Neer RM, Arnaud CD, Zanchetta JR et al. (2001) Effect of parathyroid hormone (1–34) on fractures and bone mineral density in postmenopausal women with osteoporosis. N Engl J Med 344: 1434–1441

    Article  PubMed  CAS  Google Scholar 

  • NIH Consensus Development Panel (2001) Osteoporosis prevention, diagnosis, and therapy. JAMA 285: 785–795

    Article  Google Scholar 

  • Seibel MJ, Stracke H (1997) Metabolische Osteopathien. Schattauer, Stuttgart

    Google Scholar 

  • Bone HG, Kleerekoper M (1992) Clinical review 39: Paget’s disease of bone. J Clin Endocrinol Metab 75: 1179–1182

    Google Scholar 

  • Drake WM, Kendler DL, Brown JB (2001) Consensus statement on the modern therapy of Paget’s disease of bone from a western osteoporosis alliance symposium. Clin Ther 23: 620–626

    Article  PubMed  CAS  Google Scholar 

  • Feldkamp J, Scherbaum WA (2001) Risedronsäure, neues Bisphosphonat zur Therapie und Prophylaxe der Osteoporose. Arzneimitteltherapie 19: 38–44

    Google Scholar 

  • Rogers MJ, Gordon S, Benford HL, Coxon FP, Luckman SP, Monkkonen J, Frith JC (2000) Cellular and molecular mechanisms of action of bisphosphonates. Cancer 88: 2961–2978

    Article  PubMed  CAS  Google Scholar 

  • Siris ES (1999) Goals of treatment for Paget’s disease of bone. J Bone Miner Res 14 (Suppl 2): 49–52

    Article  PubMed  Google Scholar 

  • Baitner AC, Maurer SG, Gruen MB, Di Cesare PE (2000) The genetic basis of the osteochondrodysplasias. J Pediatr Orthop 20: 594–605

    Article  PubMed  CAS  Google Scholar 

  • Candelierer G, Glorieux FH, Prud’Homme J, St.-Arnaud R (1995) Increased expression of the c-fos proto-oncogene in bone from patients with fibrous dysplasia. N Engl J Med 332: 1546–1551

    Google Scholar 

  • Tilstra DJ, Byers PH (1994) Molecular basis of hereditary dis- orders of connective tissue. Annu Rev Med 45: 149–163

    Article  PubMed  CAS  Google Scholar 

  • Vanhoenacker FM, De Beuckeleer LH, Van Hul W, Balemans W, Tan GJ, Hill SC, De Schepper AM (2000) Sclerosing bone dysplasias: genetic and radiolclinical features. Eur Radiol 10: 1423–1433

    Article  PubMed  CAS  Google Scholar 

  • Brandt KD, Doherty M, Lohmander LS (1998) Osteoarthritis. Oxford University Press, Oxford

    Google Scholar 

  • Coventry MB (1993) Proximal tibial osteotomy. J Bone Jt Surg 75-A: 196–201

    Google Scholar 

  • Fuchs S (1999) Bedeutung der Tibiakopfumstellungsosteotomie im Zeitalter von Endoprothesen. Z Orthop 37: 153–258

    Google Scholar 

  • Hassenpflug J, von Haugwitz A, Hahne HJ (1998) Long term results of tibial head osteotomy. Z Orthop 36: 154–161

    Article  Google Scholar 

  • Tönnis D, Heinecke A (1999) Acetabular and femoral anteversion: relationship with osteoarthritis of the hip. J Bone Joint Surg Am 81: 1747–1770

    Google Scholar 

  • Hochberg MC (2001) What have we learned from the large outcomes trials of COX-2 selective inhibitors? The rheumatologist’s perspective. Clin Exp Rheumatol 19 (Suppl 25): S15 - S22

    PubMed  CAS  Google Scholar 

  • Jackson LM, Hawkey CJ (2000) COX-2 selective nonsteroidal anti-inflammatory drugs: do they really offer any advantages? Drugs 59: 1207–1216

    Article  PubMed  CAS  Google Scholar 

  • Cheung HS (2000) Calcium crystal effects on the cells of the joint: implications for pathogenesis of disease. Curr Opin Rheumatol 12: 223–227

    Article  PubMed  CAS  Google Scholar 

  • Fam AG (2000) What is new about crystals other than monosodium urate? Curr Opin Rheumatol 12: 228–234

    Article  PubMed  CAS  Google Scholar 

  • Dihlmann W (1987) Gelenke - Wirbelverbindungen. Klinische Radiologie einschließlich Computertomographie - Diagnose, Differentialdiagnose, 3. Aufl. Thieme, Stuttgart New York

    Google Scholar 

  • Donatto KC (1998) Orthopedic management of septic arthritis. Rheum Dis Clin North Am 24: 275–286

    Article  CAS  Google Scholar 

  • Goldenberg DL (1998) Septic Arthritis. Lancet 351: 197–202

    Article  CAS  Google Scholar 

  • Groß DM, Forsthuber T, Tary-Lehmann M et al. (1998) Identification of LFA-1 as a candidate autoantigen in treatment-resistant Lyme-arthritis. Science 281: 703–706

    Article  PubMed  Google Scholar 

  • Gupta MN, Sturrock RD, Field M (2001) A prospective 2-year study of 75 patients with adult-onset septic arthritis. Rheumatology 40: 24–30

    Article  PubMed  CAS  Google Scholar 

  • Hogan CJ, Fang GD, Scheid WM, Linden J, Diduch DR (2001) Inhibiting the inflammatory response in joint sepsis. Arthroscopy 17: 311–315

    Article  PubMed  Google Scholar 

  • Jalava J, Skurnik M, Toivanen A, Toivanen P, Eerola E (2001) Bacterial PCR in the diagnosis of joint infection. Ann Rheum Dis 60: 287–289

    Article  PubMed  CAS  Google Scholar 

  • Krijnen P, Kaandorp CJ, Steyerberg EW, van Schaardenburg D, Moens HJ, Habbema JD (2001) Antibiotic prophylaxis for haematogenous bacterial arthritis in patients with joint disease: a cost effectiveness analysis. Ann Rheum Dis 60: 359–366

    Article  PubMed  CAS  Google Scholar 

  • Stutz G, Kuster MS, Kleinstuck F, Gachter A (2000) Arthroscopic management of septic arthritis: stages of infection and results. Knee Surg Sports Traumatol Arthrosc 8: 270–274

    Article  PubMed  CAS  Google Scholar 

  • Thaler SJ, Maguire JH (1998) Infectious arthritis. In: Fauci AS, Braunwald E, Isselbacher KJ et al. (eds) Harrison’s principles of internal medicine, 14. edn. McGraw-Hill, New York-Toronto

    Google Scholar 

  • van der Heijden IM, Wilbrink B, Schouls LM, van Embden JD, Breedveld FC, Tak PP (1999) Detection of mycobacteria in joint samples from patients with arthritis using a genus-specific polymerase chain reaction and sequence analysis. Rheumatology 38: 547–553

    Article  Google Scholar 

  • Verdrengh M, Tarkowski A (2000) Role of macrophages in Staphylococcus aureus-induced arthritis and sepsis. Arthritis Rheum 43: 2276–2282

    Article  PubMed  CAS  Google Scholar 

  • Wormser GP, Nadelmann RB, Dattwyler RJ et al. (2000) Practice guidelines for the treatment of lyme disease. Clin Infect Dis 31 (Suppl 1): 51–514

    Google Scholar 

  • Zeidler H, Zacher J, Hiepe F (Hrsg) (2001) Interdisziplinäre klinische Rheumatologie: Innere Medizin - Orthopädie - Immunologie. Springer, Berlin Heidelberg New York Tokyo

    Google Scholar 

  • Breedfeld FC, Dayer JM (2000) Leflunomide: mode of action in the treatment of rheumatoid arthritis. Ann Rheum Dis 59: 841–849

    Article  Google Scholar 

  • Choy EH, Panayi GS (2001) Cytokine pathways and joint inflam- mation in rheumatoid arthritis. N Engl J Med 344: 907–916

    Article  PubMed  CAS  Google Scholar 

  • Crofford LJ, Lipsky PE, Brooks P, Abramson SB, Simon LS, Van De Putte LB (2000) Basic biology and clinical application of specific cyclooxygenase-2 inhibitors. Arthritis Rheum 43: 4–13

    Article  PubMed  CAS  Google Scholar 

  • Firestein GS (2001) Etiology and pathogenesis of rheumatoid arthritis. In: Ruddy S, Harris ED, Sledge CB (eds) Kelley’s textbook of rheumatology. WB Saunders, Philadelphia

    Google Scholar 

  • Furst DE et al. (2002) Updated consensus statement on biological agents for the treatment of rheumatoid arthritis and other rheumatic diseases. Ann Rheum Dis 61 (Suppl II): ii2-ii7

    Google Scholar 

  • Harris ED (2001) Clinical features of rheumatoid arthritis. In: Ruddy S, Harris ED, Sledge CB (eds) Kelley’s textbook of rheumatology. WB Saunders, Philadelphia

    Google Scholar 

  • Markham A, Lamb HM (2000) Infliximab: a review of its use in the management of rheumatoid arthritis. Drugs 59: 1341–1359

    Article  CAS  Google Scholar 

  • O’Dell JR, Scott DL (1999) Rheumatoid arthritis: new developments in the use of existing therapies. Rheumatology 38 (Suppl 2): 24–26

    PubMed  Google Scholar 

  • Plant MJ, Jones PW, Saldatvala J, Oilier WE, Dawes PT (1998) Patterns of radiological progression in early rheumatoid arthritis: results of an 8 year prospective study. J Rheumatol 25: 417–426

    PubMed  CAS  Google Scholar 

  • Ryan L, Brooks P (1999) Disease modifying antirheumatic drugs. Curr Opin Rheumatol 11: 161–166

    Article  PubMed  CAS  Google Scholar 

  • Spencer-Green G (2000) Etanercept (Enbrel): update on therapeutic use. Ann Rheum Dis 59 (Suppl 1): i46 - i49

    Article  PubMed  CAS  Google Scholar 

  • Taylor PC (2001) Anti-tumor necrosis factor therapies. Curr Opin Rheumatol 13: 164–169

    Article  PubMed  CAS  Google Scholar 

  • Verhoeven AC, Boers M, Tugwell P (1998) Combination therapy in rheumatoid arthritis: An updated systematic review. Br J Rheumatol 37: 1102–1109

    Google Scholar 

  • Bywaters EGL (1971) Still’s disease in the adult. Ann Rheum Dis 31: 121–133

    Article  Google Scholar 

  • Cush JJ, Medsger TA Jr, Christy WC et al. (1987) Adult-onset Still’s disease. Clinical course and outcome. Arthritis Rheum 30: 186–194

    Google Scholar 

  • Delpech M, Grateau G (2001) Genetically determined recurrent fevers. Curr Opin Immunol 13: 539–542

    Article  PubMed  CAS  Google Scholar 

  • Fautrel B, Borget C, Rozenberg S et al. (1999) Corticosteroid sparing effect of low dose methotrexate treatment in adult Still’s disease. J Rheumatol 26: 373–378

    PubMed  CAS  Google Scholar 

  • Fautrel B, Le Moel G, Saint-Marcoux B et al. (2001) Diagnostic value of ferritin and glycosylated ferritin in adult onset Still’s disease. J Rheumatol 28: 322–329

    PubMed  CAS  Google Scholar 

  • Khraishi M, Fam AG (1991) Treatment of fulminant adult Still’s disease with intravenous pulse methylprednisolone therapy. J Rheumatol 18: 1088–1090

    PubMed  CAS  Google Scholar 

  • Pouchot J, Sampalis JS, Beaudet F et al. (1991) Adult Still’s disease: Manifestations, disease course, and outcome in 62 patients. Medicine 70: 118–136

    Article  PubMed  CAS  Google Scholar 

  • Yamaguchi M, Ohta A, Tsunematsu T et al. (1992) Preliminary criteria for classification of adult Still’s disease. J Rheumatol 19: 424–430

    PubMed  CAS  Google Scholar 

  • Adam D, Scholz H, Helmerking M (2000) Short-course antibiotic treatment of 4782 culture-proven cases of group A streptococcal tonsillopharyngitis and incidence of poststreptococcal sequelae. J Infect Dis 182: 509–516

    Article  PubMed  CAS  Google Scholar 

  • Albert DA, Harel L, Karrison T (1995) The treatment of rheuma- tic carditis: a review and meta-analysis. Medicine 74: 1–12

    Article  PubMed  CAS  Google Scholar 

  • Bisno AL (2000) Nonsuppurative poststreptococcal sequelae: Rheumatic fever and glomerulonephritis. In: Mandell GL, Bennett JE, Dolin R (eds) Principles and practice of infectious diseases, 5th edn. Churchill Livingstone, Philadelphia, p 2117–2128

    Google Scholar 

  • Del Mar CB, Glasziou PP, Spinks AB (1/2002) Antibiotics for sore throat (Cochrane Review). In: The Cochrane Library. Oxford: Update Software

    Google Scholar 

  • Gibofsky A, Kerwar S, Zabriskie JB (1998) Rheumatic fever. The relationship between host, microbe, and genetics. Rheum Dis Clin N Am 24: 237–259

    Google Scholar 

  • Lue HC, Wu MH, Wang JK, Wu FF, Wu YN (1994) Long-term outcome of patients with rheumatic fever receiving benzathine penicillin G prophylaxis every three weeks versus every four weeks. J Pediatr 125: 812–816

    Article  PubMed  CAS  Google Scholar 

  • Oen K (2000) Comparative epidemiology of the rheumatic diseases in children. Curr Opin Rheumatol 12: 410–414

    Article  PubMed  CAS  Google Scholar 

  • Olivier C (2000) Rheumatic fever–is it still a problem? J Antimicrob Chemother 45: 13–21

    Article  PubMed  CAS  Google Scholar 

  • Special writing group of the committee on rheumatic fever, endocarditis and Kawasaki disease of the council on cardiovascular disease in the young of the American Heart Association (1992) Guidelines for the diagnosis of rheumatic fever. Jones criteria,1992 update. JAMA 2069–2073

    Google Scholar 

  • Brandt J, Haibel H, Comely D et al. (2000) Successful treatment of active ankylosing spondylitis with the anti-tumor necrosis factor alpha monoclonal antibody infliximab. Arthritis Rheum 43: 1346–1352

    Article  PubMed  CAS  Google Scholar 

  • Calin A, Porta J, Fries JF, Schurmann DJ (1977) Clinical history as a screening test for ankylosing spondylitis. JAMA 237: 2613–2614

    Article  PubMed  CAS  Google Scholar 

  • Dougados M, van der Linden S, Juhlin R et al (1991) The European Spondylarthropathy Study Group preliminary criteria for the classification of spondylarthropathy. Arthritis Rheum 34: 1218–1227

    Article  PubMed  CAS  Google Scholar 

  • Goie HS, Steven MM, van der Linden S, Cats A (1985) Evaluation of diagnostic criteria for ankylosing spondylitis: a comparison of the Rome, New York and modified New York criteria in patients with a positive clinical history screening test for ankylosing spondylitis. Br J Rheumatol 24: 242–249

    Google Scholar 

  • Mau W, Zeidler H, Mau R et al. (1990) Evaluation of early diagnostic criteria for ankylosing spondylitis in a 10 year follow-up. Z Rheumatol 49: 82–87

    PubMed  CAS  Google Scholar 

  • Olivieri I, Salvarani C, Cantini F, Ciancio G, Padula A (2001) Ankylosing spondylitis and undifferentiated spondyloarthropathies: a clinical review and description of a disease subset with older age at onset. Curr Opin Rheumatol 13: 280–284

    Article  PubMed  CAS  Google Scholar 

  • Toivanen A (2001) Bacteria-triggered reactive arthritis: implications for antibacterial treatment. Drugs 61: 343–351

    Article  PubMed  CAS  Google Scholar 

  • Toivanen A, Toivanen P (2000) Reactive arthritis. Curr Opin Rheumatol 12: 300–305

    Article  PubMed  CAS  Google Scholar 

  • van der Linden S, van der Heijde D (2000) Clinical aspects, outcome assessment, and management of ankylosing spondylitis and postenteric reactive arthritis. Curr Opin Rheumatol 12: 263–268

    Article  Google Scholar 

  • Girolomoni G, Abeni D (2001) Anti-tumor necrosis factor alpha therapy in psoriatic arthritis and psoriasis. Arch Dermatol 137 (6): 784–785

    PubMed  CAS  Google Scholar 

  • Helliwell PS, Wright V (1994) Psoriatic arthritis. In: Klippel JH, Dieppe PA (eds) Rheumatology. Mosby, St. Louis

    Google Scholar 

  • Jones G, Crotty M, Brooks P (2000) Interventions for psoriatic arthritis. Cochrane Database Syst Rev 3: CD000212

    Google Scholar 

  • Moll JM, Wright V (1973) Psoriatic arthritis. Semin Arthritis Rheum 3: 55–78

    Article  PubMed  CAS  Google Scholar 

  • Mrowietz U (2001) Advances in systemic therapy for psoriasis. Clin Exp Dermatol 26: 362–367

    Article  PubMed  CAS  Google Scholar 

  • Patel S, Veale D, Fitzgerald O, McHugh NJ (2001) Psoriatic arthri- tis-emerging concepts. Rheumatology (Oxford) 40: 243–246

    Article  CAS  Google Scholar 

  • Spadaro A, Riccieri V, Sili-Scavalli A, Sensi F, Taccari E, Zoppini A (1995) Comparison of cyclosporin A and methotrexate in the treatment of psoriatic arthritis: a one-year prospective study. Clin Exp Rheumatol 13 (5): 589–593

    PubMed  CAS  Google Scholar 

  • Veys EM, Mielants H (1994) Enteropathic arthropathies. In: Klippel JH, Dieppe PA (eds) Rheumatology. Mosby, St. Louis

    Google Scholar 

  • Zachariae H (1999) Renal toxicity of long-term ciclosporin. Scand J Rheumatol 28: 65–68

    Article  PubMed  CAS  Google Scholar 

  • Chamot AM, Benhamou CL, Kahn MF, Beraneck L, Kaplan G, Prost A (1987) Le syndrome hyperosotse osteite (SAPHO). Resultats d’une enquete nationale: 85 observations. Rev Rhum Mal Osteoartic 187–196

    Google Scholar 

  • Edlund E, Johnsson U, Lidgren L, Petterson H, Sturfelt G, Svensson B et al. (1988) Palmoplantar pustulosis and sternocostoclavicular arthro-osteitis. Ann Rheum Dis 47: 809–815

    Article  PubMed  CAS  Google Scholar 

  • Hayem G, Bouchaud-Chabot A, Benali K, Roux S, Palazzo E, Silbermann-Hoiffman O et al. (1999) SAPHO syndrome: a longterm follow-up study of 120 cases. Semin Arthritis Rheum 29: 251–256

    Article  Google Scholar 

  • Kahn MF, Bouvier MB, Palazzo E, Tebib J, Colson F (1991) Sternoclavicular pustulotitc osteitis (SAPHO). 20 year interval between skin and bon lesions. J Rheumatol 18: 1104–1108

    PubMed  CAS  Google Scholar 

  • Kahn MF, Chamot AM (1992) SAPHO syndrome. Rheum Dis Clin N Am 18: 225–246

    CAS  Google Scholar 

  • Kahn MF, Khan MA (1994) The SAPHO syndrome. Ballières Clin Rheumatol 8: 333–362

    Article  CAS  Google Scholar 

  • Sonozaki H, Mitsui H, Miyanaga Y, Okitsu K, Igarashi M, Hayashi Yet al. (1981) Clinical features of 53 cases with pustlotic arthroosteitis. Ann Rheum Dis 40: 547–553

    Article  PubMed  CAS  Google Scholar 

  • Van Doornum S, Barraclough D, McColl G, Wicks I (2000) SAPHO: Rare or just not recognized? Semin Arthritis Rheum 30: 70–77

    Article  PubMed  Google Scholar 

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Schröder, J.O. et al. (2003). Erkrankungen von Knochen, Muskeln und Gelenken. In: Schölmerich, J., et al. Medizinische Therapie in Klinik und Praxis. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-662-12451-2_7

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