Vulvakarzinom

  • H. G. Meerpohl

Zusammenfassung

Das Vulvakarzinom ist mit einem Anteil von etwa 4% ein seltener Tumor des weiblichen Genitaltraktes. In über 90% der Fälle handelt es sich histologisch um Plattenepithelkarzinome. Melanome, Adenokarzinome und Sarkome der Vulva werden nur selten diagnostiziert. Während sich die Inzidenz von In-situ-Karzinomen seit Mitte der 70er Jahre beinahe verdoppelt hat, ist der Anteil an invasiven Karzinomen in diesem Zeitraum unverändert geblieben (Sturgeon et al. 1992).

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

Literatur

  1. Belinson JL, Stewart JA, Richards A et al. (1985) Bleomycin, vincristine, mitomycin C, and cisplatin in the management of gynecologic squamous cell cancer. Gynecol Oncol 20: 387PubMedCrossRefGoogle Scholar
  2. Boronow RC, Hickmann BT, Reagan MT et al. (1987) Combined therapy as an alternative to exenteration for locally advanced vulvovaginal cancer. II. Results, complications and dosimetric and surgical considerations. Am J Clin Oncol 10: 171PubMedCrossRefGoogle Scholar
  3. Brinton LA, Nasca PC, Mallin K et al. (1990) Case control study of cancer of the vulva. Obstet Gynecol 75: 859PubMedGoogle Scholar
  4. Chafe W, Richard A, Morgan L et al. (1988) Unrecognized invasive carcinoma in vulvar epithelial neoplasia ( VIN ). Gynecol Oncol 31: 154PubMedCrossRefGoogle Scholar
  5. Creasman WT (1990) New gynecologic cancer staging. Obstet Gynecol 75: 287PubMedGoogle Scholar
  6. Deppe G, Bruckner HW, Cohen CJ (1977) Adriamycin treatment of advanced vulvar carcinoma. Obstet Gynecol 50 [Suppl 101: 13Google Scholar
  7. Friedrich EJ, Wikinson Ef Fu Ys (1980) Carcinoma in situ of the vulva: A continuing challenge. Obstet Gynecol 136: 801–806Google Scholar
  8. Gross G, Hageorn M, Ikenberg H et al. (1985): Bowenoid papulosis: Presence of human papilomavirus (HPV) structural antigens and HPV 16 related DNA sequences. Arch Dermatol 121: 858PubMedCrossRefGoogle Scholar
  9. Hacker N (1994) Vulvar cancer. In: Berek J, Hacker N (eds) Practical Gynecologic Oncology, 2nd edn. Williams and Wikins, Baltimore, pp 403–439Google Scholar
  10. Hacker N, Berek JS, Juillard GJF, Lagsse LD et al. (1993) Preoperative radiation therapy for locally advanced vulvar cancer. Cancer 54: 2056CrossRefGoogle Scholar
  11. Homesley HD (1985) Carcinoma of the vulva. In: Conn HF (ed) Conn’s current therapy. Saunder, Philadelphia, p 85Google Scholar
  12. Iversen T, Aas M (1983) Lymph drainage from the vulva. Gynecol Oncol 16: 179PubMedCrossRefGoogle Scholar
  13. Kaern J, Iversen T, Trope C et al. (1992) Flow cytometric DNA measurements in squamous cell carcinoma of the vulva: an important prognostic method. Int Gynecol Cancer 2: 169CrossRefGoogle Scholar
  14. Stehmann F, Bundy B, Bell J et al. (1992) Groin dissection versus groin radiation in carcinoma of the vulva: a gynecologic group study. Int J Radiat Oncol Biol Phys 24: 389CrossRefGoogle Scholar
  15. Sturgeon SR, Briton LA, Devesa SS, Kurman RJ (1992) In situ and invasive vulvar cancer incidence trends (1973 to 1987). Am J Obstet Gynecol 166: 1482PubMedCrossRefGoogle Scholar
  16. Thomas G, Bembo A, DePetrillo A et al. (1989) Concurrent radiation and chemotherapy in vulvar carcinoma. Gynecol Oncol 34: 263PubMedCrossRefGoogle Scholar
  17. Trope C, Johnson JE, Larrson G et al. (1980) Bleomycin alone or combined with mitomycin C in treatment of advanced or recurrent sqamous carcinoma of the vulva. Cancer Treat Rep 64: 639PubMedGoogle Scholar

Copyright information

© Springer-Verlag Berlin Heidelberg 1997

Authors and Affiliations

  • H. G. Meerpohl

There are no affiliations available

Personalised recommendations