EKG-Klassifikation: Tachykardien

  • U. Dorwarth
  • A. Gerth
  • R. Haberl
  • E. Hoffmann
  • M. Näbauer
  • C. Reithmann
  • T. Remp
  • G. Steinbeck
  • P. Steinbigler


Eine Tachykardie ist definiert als eine Herzfequenz von mehr als 100/min unabhängig von der Ursache. Diese Tachykardie kann im Sinusknoten, Vorhof, AV-Überleitungsgewebe und in der Kammer entstehen. Als elektrophysiologische Entstehungsmechanismen müssen die fokale Impulsbildung und Kreiserregungen diskutiert werden.


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Literatur zu Sektion IV Kap.24

  1. Acute Infarction Ramipril Efficacy (AIRE) Study Investigators (1993) Effect of ramipril on mortality and morbidity of survivors of acute myocardial infarction with clinical evidence of heart failure. Lancet 342: 821–828Google Scholar
  2. Akselrod S, Gordon D, Ubel FA, Shannon DC, Berger AC, Cohen RJ (1981) Power spectrum analysis of heart rate fluctuation: a quantitative probe of beat-to-beat cardiovascular control. Science 21/4504: 220–222Google Scholar
  3. Allessie MA, Bonke FIM, Schopman FJG (1973) Circus movement in rabbit atrial muscle as a mechanism of tachycardia. Circ Res 33: 54–62Google Scholar
  4. Allessie MA, Bonke FIM, Schopman FJG (1977) Circus movement in rabbit atrial muscle as a mechanism of tachycardia. III.,,The leading circle“ concept: A new model of circus movement in cardiac tissue without the involvement of an anatomical obstacle. Circ Res 41: 9–18PubMedGoogle Scholar
  5. Antiarrhythmics Versus Implantable Defibrillators (AVID) Investigators (1997) A comparison of antiarrhythmic drug therapy with implantable defibrillators in patients resuscitated from near-fatal ventricular arrhythmias. N Engl J Med 337; 1576Google Scholar
  6. Anumonwo JMB, Jalife J (1995) Cellular and subcellular mechanisms of pacemaker activity initiation and synchronization in the heart. In: Zipes D, Jalife J (eds) Cardiac Electrophysiology: From Cell to Bedside. Saunders, Philadelphia, pp 151–164Google Scholar
  7. Arruda MS, McClelland JH, Wang X et al. (1998) Development and validation of an ECG algorithm for identifying accessory pathway ablation site in Wolff-Parkinson-White syndrome. J Cardiovasc Electrophysiol 9: 2–12PubMedGoogle Scholar
  8. Bazett HC (1920) An analysis of the time-relations of the electrocardiograms. Heart 7: 353–370Google Scholar
  9. Bigger JT Jr, Fleiss JL, Steinman RC, Rolnitzky LM, Kleiger RE, Rottman JN (1992) Correlations among time and frequency domain measures of heart rate variability two weeks after acute myocardial infarction. Am J Cardiol 69 /9: 891–898PubMedGoogle Scholar
  10. Bigger JT, Fleiss JL, Kleiger R, Miller JP, Rolnitzky LM (1984) Multicenter post-infarction research group. The relationships among ventricular arrhythmias, left ventricular dysfunction, and mortality in the 2 years after myocardial infarction. Circulation 69: 250–258PubMedGoogle Scholar
  11. Borggrefe M, Seipel L, Breithardt G (1984) Klinische and elektrophysiologische Befunde bei Patienten mit Synkopen nach Myokardinfarkt. Z Kardiol 73: 297–303PubMedGoogle Scholar
  12. Boston Area Anticoagulation Trial for Atrial Fibrillation Investigators (1990) The effect of low-dose warfarin on the risk of stroke in patients with nonrheumatic atrial fibrillation. N Engl J Med 323: 1505–1551Google Scholar
  13. Breithardt G, Borggrefe M, Karbenn U, Abendroth RR, Yeh HL, Seipel L (1982) Prevalence of late potentials in patients with and without ventricular tachycardia: Correlation with angiographic findings. Am J Cardiol 49: 1932–1937PubMedGoogle Scholar
  14. Breithardt G, Lüderitz B, Schlepper M (1989) Empfehlungen für die Indikation zur permanenten Schrittmacherimplantation der Klinischen Kommission in Zusammenarbeit mit der Arbeitsgruppe „Schrittmacher“ and der Arbeitsgruppe „Rhythmusstörungen” der Deutschen Gesellschaft für Herz-and Kreislaufforschung. Z Kardiol 78: 212–217Google Scholar
  15. Breithardt G, Seipel L, Haerten K, Abendroth PR, Loogen F (1979) Effektivitätskontrolle der antiarrhythmischen Therapie bei Patienten mit chronisch-rezidivierenden ventrikulären Tachykardien mittels elektrophysiologischer Stimulationsverfahren. Z Kardiol 68: 725–730PubMedGoogle Scholar
  16. Brugada P, Brugada J (1992) Right bundle branch block, persistent ST segment elevation, and sudden death: a distinct clinical and electrocardiographic syndrome. A multicenter report. J Am Coll Cardiol 20: 1391–1396PubMedGoogle Scholar
  17. Brugada P, Brugada J, Mont L, Smeets J, Andries EW (1991) A new approach to the differential diagnosis of a regular tachycardia with a wide QRS complex. Circulation 83: 1649–1659PubMedGoogle Scholar
  18. Burkart F, Pfisterer M, Kiowksi W, Follath F, Burckhardt D (1990) Effect of antiarrhythmic therapy on mortality in survivors of myocardial infarction with asymptomatic complex ventricular arrhythmias: Basel Antiarrhythmic Study of Infarct Survival (BASIS). J Am Coll Cardio116: 1711–1718Google Scholar
  19. Capucci A et al (1994) Conversion of recent onset atrial fibrillation to sinus rhythm by a single oral loading dose of propafenone or flecainide. Am J Cardiol 74: 503PubMedGoogle Scholar
  20. Cardiac Arrhythmia Suppression Trial (CAST) Investigators (1989) Preliminary report: Effect of encainide and flecainide on mortality in a randomized trial of arrhythmia suppression after myocardial infarction. N Engl J Med 321: 406–412Google Scholar
  21. Cardiac Insufficiency Bisoprolol Study II (CIBIS-II): a randomised trial. Lancet. 1999; 353: 9–13Google Scholar
  22. Carlsten J, Holmstrom H, Hagel P (1994) Oxygen pressure as bio- sensor for rate adaptive cardiac pacing. PACE 17: 1939–1943PubMedGoogle Scholar
  23. Cauchemez B et al (1996) Electrophysiological effects of catheter ablation of inferior vena cava-tricuspid annulus isthmus in common atrial flutter. Circulation 93: 284PubMedGoogle Scholar
  24. Ceremuzynski L, Kleczar E, Krzeminska-Pakula M et al. (1992) Effect of amiodarone on mortality after myocardial infarction: a double-blind, placebo-controlled, pilot study. J Am Coll Cardi-01 20: 1056–1062Google Scholar
  25. Chen SA, Ching TT, Shih-Huang L, Man-Song C (1998) AV nodal reentrant tachycardia with unusal characteristics: lesions from radio-frequency catheter ablation. J Cardiovasc Electrophysiol 9: 321–333PubMedGoogle Scholar
  26. Chu-pak Lau (1992) The range of sensors and algorithms used in rate adaptive cardiac pacing. PACE 15: 557–211Google Scholar
  27. Connelly DT (1993) Initial experience with a new single chamber, dual sensor rate responsive pacemaker. The Topaz Study Group. PACE 16 (9): 1833–1841PubMedGoogle Scholar
  28. Coplen SE, Antman EM, Berlin JA, Hewitt P, Chalmers TC (1990) Efficacy and safety of quinidine therapy for maintenance of sinus rhythm after cardioversion. Circulation 82: 1106–1116PubMedGoogle Scholar
  29. Cranefield PF (1977) Action potentials, after-potentials and arrhythmias. Circ Res 41: 415–423PubMedGoogle Scholar
  30. Cranefield PF, Wit AL, Hoffman BF (1973) Genesis of cardiac arrhythmias. Circulation 47: 190–204PubMedGoogle Scholar
  31. Cripps TR, Malik M, Farrell TG, Camm AJ (1991) Prognostic value of reduced heart rate variability after myocardial infarction: clinical evaluation of a new analysis method. Br Heart J 65/i: 14–59Google Scholar
  32. Cummins RO, Graves JR, Larsen MP et al. (1993) Out-of-hospital transcutaneous pacing by emergency medical technicians in patients with asystolic cardiac arrest. N Engl J Med 328: 1377–5382PubMedGoogle Scholar
  33. Deutsche Gesellschaft für Kardiologie - Herz-Kreislauf-Forschung and Arbeitsgruppe Herzschrittmacher: Empfehlungen zur Schrittmachernachsorge (1995) Z Kardiol 84: 420–421Google Scholar
  34. Dhingra RC, Palileo E, Strasberg B et al. (5981) Significance of the HV interval in 517 patients with chronic bifascicular block. Circulation 64: 1265–1271Google Scholar
  35. Ditchey RV, Karliner JS (1981) Safety of electrical cardioversion in patients without digitalis toxicity. Ann Int Med 95: 676–679PubMedGoogle Scholar
  36. Dougherty CM, Burr RL (1992) Comparison of heart rate variability in survivors and nonsurvivors of sudden cardiac arrest. Am J Cardiol 70 /4: 441–448PubMedGoogle Scholar
  37. Dreifus LS, Haiat R, Watanabe Y et al. (5971) A possible mechanism of sudden death in patients with WPW-syndrome. Circulation 43; 520Google Scholar
  38. Faerestrand S, Ohm OJ (1994) Clinical study of a new activity sensor for rate adaptive pacing controlled by electrical signs generated by the kinetic energy of a moving magnetic ball. PACE 17 (11 Pt 2): 1944–1949Google Scholar
  39. Faerestrand S, Ohm OJ, Stangeland L, Heynen H, Moore A (1994) Long-term clinical performance of a central venous oxygen saturation sensor for rate adaptive cardiac pacing. PACE 17 (8): 1355–1372PubMedGoogle Scholar
  40. Fananapazir L, Epstein ND, Curie] RV, Panza JA, Tripodi D, McAreavey D (1994) Long-term results of dual-chamber (DDD) pacing in obstructive hypertrophic cardiomyopathy. Circulation 90: 2731–2742PubMedGoogle Scholar
  41. Farrell TG, Bashir Y, Cripps T, Malik M, Ploniecki J, Bennett ED, Ward DE, Camm AJ (1991) Risk stratification of arrhythmic events in postinfarction patients based on heart rate variability, ambulatory electrocardiographic variables and the signal-averaged electrocardiogram. J Am Coll Cardiol 18 /3: 687–697PubMedGoogle Scholar
  42. Ferrer MI (1968) The sick sinus syndrome in atrial disease. JAMA 206: 645–646PubMedGoogle Scholar
  43. Fiaker GC, Blackshear JL, McBride R, Kronmal RA, Halprin JL, Hart RG on behalf of the Stroke Prevention in Atrial Fibrillation Investigators (1992) Antiarrhythmic drug therapy and cardiac mortality in atrial fibrillation. J Am Coll Cardiol 20: 527–532Google Scholar
  44. Franke H (1963) Über das Karotissinus-Syndrom und den sogenann- ten hyperaktiven Karotissinus-Reflex. Schattauer, StuttgartGoogle Scholar
  45. Frye RL, Colins JJ, DeSanctis RW et al. (1984) Guidelines for permanent pacemaker implantation, May 1984. A report of the Joint American College of Cardiology/American Heart Association Task Force on Assessment of Cardiovascular Procedures (Subcommittee on Pacemaker Implantation). Circulation 70: 331A-339 AGoogle Scholar
  46. Gann D, Tolentino A, Samet P (1979) Electrophysiologic evaluation of elderly patients with sinus bradycardia. A long-term follow-up study. Ann Intern Med 90: 24–29PubMedGoogle Scholar
  47. Godtfredsen J (1982) Atrial fibrillation: course and prognosis - a follow-up study of 1212 cases. In: Kulbertus HE, Olsson SB, Schlepper M (eds) Atrial fibrillation. Astra, Mölndal, p 134Google Scholar
  48. Greene HL, Graham EL, Werner JA et al. (1983) Toxic and therapeutic effects of amiodarone in the treatment of cardiac arrhythmias. JACC 2: 1114–1128PubMedGoogle Scholar
  49. Gulamhusein S, Ko P, Carruthers SG, Klein GJ (1982) Acceleration of the ventricular response during atrial fibrillation in the Wolff-Parkinson-White syndrome after verapamil. Circulation 65: 348–354PubMedGoogle Scholar
  50. Gussak I et al. (1999) The Brugada syndrome: clinical, electrophysiologic, and genetic aspects. J Am Coll Cardiol 33: 5–15PubMedGoogle Scholar
  51. Haberl R, Juge G, Pulter R, Steinbeck G (1988) Comparison of frequency and time domain analysis of the signal-averaged electrocardiogram in patients with ventricular tachycardia and coronary artery disease: Methodologic validation and clinical relevance. JACC 12: 150–158PubMedGoogle Scholar
  52. Haberl R, Steinbeck G (1987) Ableitung ventrikulärer Spätpotentiale von der Körperoberfläche–Pathophysiologie und diagnostische Wertigkeit. Internist 28: 159–563PubMedGoogle Scholar
  53. Hagemeijer F, Houwe E van (5975) Titrated energy cardioversion of patients on digitalis. Br Heart J 37: 5303–5307Google Scholar
  54. Haverkamp W, Hjördt M, Borggrefe M, Breithardt G (1995) Torsade de pointes und QT-Syndrome. Medizinische Klinik 90: 240–245PubMedGoogle Scholar
  55. Heger JJ, Prystowsky EN, Jackman WM et al. (1981) Amiodarone–clinical efficacy and electrophysiology during long-term therapy for recurrent ventricular tachycardia or ventricular fibrillation. N Engl J Med 305: 539–545PubMedGoogle Scholar
  56. Hoffmann E, Reithmann C, Neuser H, Nimmermann P, Remp T, Steinbeck G (5998) Repetitive monomorphe ventrikuläre Tachykardie (Typ Gallavardin): Klinische und elektrophysiologische Charakteristika von 20 Patienten. Z Kardiol 87: 353–363Google Scholar
  57. Hoffmann E, Steinbeck G (1989) Transkutane Stimulation zur Notfalltherapie. Internist 30: 73–76PubMedGoogle Scholar
  58. Hoffmann E, Steinbeck G (1995) Katheterablation supraventrikulärer Tachykardien. Springer, Berlin Heidelberg New York Tokio Hoffmann E, Steinbeck G ( 1999 ) Interventionelle Elektrophysiologie. Springer, Berlin Heidelberg New York TokioGoogle Scholar
  59. Holmgren A (1968) Obere und untere Herzfrequenz in Abhängigkeit vom Alter. In: Reindell H, Keul J, Doll E (Hrsg) Herzinsuffizienz, Pathophysiologie und Klinik. Thieme, Stuttgart, S 423–426Google Scholar
  60. Horowitz LN, Josephson ME, Farshidi A, Spielman SR, Michelson EL, Greenspan AM (1978) Recurrent sustained ventricular tachycardia. 2. Role of the electrophysiologic study in selection of antiarrhythmic regimens. Circulation 58: 986–997PubMedGoogle Scholar
  61. Jackman WM, Beckman KJ, McClelland JH (1992) Treatment of supraventricular tachycardia due to atrioventricular nodal reentry by radiofrequency catheter ablation of slow pathway conduction. N Engl J Med 327: 313–318PubMedGoogle Scholar
  62. Jackman WM, Wang X, Friday KJ, Roman CA, Moulton KP, Beckman KJ, McClelland JH et al. (1991) Catheter ablation of accessory atrioventricular pathways (Wolff-Parkinson-White syndrome) by radiofrequency current. N Engl J Med 324: 5605–1651Google Scholar
  63. Janse MJ, Capell FJL van, Morsink H, Kleber AG, Wilms-Schopman F, Cardinal R, Naumann d’Alnoncourt C, Durrer D (1980) Flow of injury current and patterns of excitation during early ventricular arrhythmias in acute regional myocardial ischemia in isolated porcine and canine hearts. Evidence for two different arrhythmogenic mechanisms. Circ Res 47: 151–165PubMedGoogle Scholar
  64. Jelinek MV, Lown B (1974) Exercise stress testing for exposure of cardiac arrhythmias. Prog Cardiovasc Dis 16: 497–522PubMedGoogle Scholar
  65. Jervell A, Lange-Nielsen F (5957) Congenital deaf-mutism, functional heart disease with prolongation of the QT- interval, and sudden death. Am Heart J 54: 59–68Google Scholar
  66. Josephson ME, Seides SF (eds) (5979) Clinical cardiac electrophysiology - Techniques and interpretation. Lea Febiger, PhiladelphiaGoogle Scholar
  67. Katritsis D, Shakespeare CF, Camm AJ (5993) New and combined sensors for adaptive-rate pacing. Clin Cardiol 16/3: 240–248Google Scholar
  68. Kennedy HL, Whitlock JA, Sprague ME, Kennedy LJ, Buckingham TA, Goldberg RJ (1985) Long-term follow-up of asymptomatic healthy subjects with frequent and complex ventricular ectopy. N Engl J Med 312: 193–197PubMedGoogle Scholar
  69. Kleiger R, Lown B (1966) Cardioversion and digitalis, II. Clinical studies. Circulation 33: 878–887PubMedGoogle Scholar
  70. Klein GJ, Guiraudon G, Guiraudon C, Yee R (1994) The nodoventricular Mahaim pathway: an endangered concept? Circulation 90: 636–638PubMedGoogle Scholar
  71. Koster RW, Dunning AJ (1985) Intramuscular lidocaine for prevention of lethal arrhythmias in the prehospitalization phase of acute myocardial infarction. N Engl J Med 313: 1105–1550PubMedGoogle Scholar
  72. Krahn AD; Klein GJ; Yee R; Takle-Newhouse T; Norris-C (5999) Use of an extended monitoring strategy in patients with problematic syncope. Circulation. 99/3: 406–450Google Scholar
  73. Kulbertus HE, Demoulin JC (5976) Pathological basis of concept of left hemiblock. In: Wellens HJJ, Lie KH, Janse MT (eds) The conduction system of the heart. Stenfert Kroese, Leiden, pp 287–295Google Scholar
  74. Kulbertus HE, Rutten DL, Dubois M, Petit JM (1978) Prognostic significance of left anterior hemiblock with right bundle branch block in mass screening. Am J Cardiol 45: 385Google Scholar
  75. La Rovere MT, Bigger JT Jr, Marcus FI, Mortara A, Schwartz PJ (5998) Baroreflex sensitivity and heart-rate variability in prediction of total cardiac mortality after myocardial infarction. ATRAMI (Autonomic Tone and Reflexes After Myocardial Infarction) Investigators. Lancet 54/351: 478–484Google Scholar
  76. Lee SH et al. (1998) Comparisons of quality of life and cardiac performance after complete atrioventricular junction ablation and atrioventricular junction modification in patients with medically refractory atrial fibrillation. J Am Coll Cardiol 35: 637Google Scholar
  77. Leitner E-R von (1982) Wertigkeit elektrokardiographischer Untersuchungsmethoden zur Diagnostik bradykarder Rhythmusstörungen. Med. Habilitationsschrift, Universität BerlinGoogle Scholar
  78. Leitner E-R von (1983) Nicht-invasive Verfahren einschließlich Holter-Monitoring. In: Luderitz B (Hrsg) Handbuch der inneren Medizin–Herzrhythmusstörungen. Springer, Berlin Heidelberg New York Tokio, S 425–484Google Scholar
  79. Lemke B, Fischer W, Schulten KH (1996) Richtlinien zur Herzschrittmachertherapie-Indikation, Systemwahl, Nachsorge. Z Kardiol 85: 615–628Google Scholar
  80. Levy S et al. on behalf of the Working Group on Arrhythmias of the European Society of Cardiology (5998) Atrial fibrillation - Current knowledge and recommendations for management. European Heart Journal 19: 1294–5320Google Scholar
  81. Lombardi F, Sandrone G, Pernpruner S, Sala R, Garimoldi M, Cerutti S, Baselli G et al. (1987) Heart rate variability as an index of sympathovagal interaction after acute myocardial infarction. Am J Cardiol 60/56: 1239–1245Google Scholar
  82. Lown B (1967) Electrical reversion of cardiac arrhythmias. Br Heart J 29: 469–489PubMedGoogle Scholar
  83. Lown B, Wolf M (1971) Approaches to sudden death from coronary heart disease. Circulation 44: 530–542Google Scholar
  84. Lown B, Wyatt NF, Levine HD (5960) Paroxysmal atrial tachycardia with block. Circulation 25: 129–143Google Scholar
  85. Luderitz B (1983) Betarezeptorenblocker und Antiarrhythmika im engeren Sinne. In: Luderitz B (Hrsg) Handbuch der Inneren Medizin–Herzrhythmusstörungen. Springer, Berlin Heidelberg New York Tokio, S 809–896Google Scholar
  86. Luderitz B (5993) Therapie der Herzrhythmusstörungen. Springer, Berlin Heidelberg New York TokioGoogle Scholar
  87. Luderitz B (1995) Bradykarde Rhythmusstörungen. In: Paumgartner G, Riecker G (Hrsg) Therapie Innerer Krankheiten, 8.Aufl. Springer, Berlin Heidelberg New York Tokio, S 25Google Scholar
  88. Luderitz B (5998) Therapie der Herzrhythmusstörungen, 5. Aufl. Springer, Berlin Heidelbeg New York TokioGoogle Scholar
  89. Luderitz B (Hrsg) (1986) Herzschrittmacher - Therapie and Diagnostik kardialer Rhythmusstörungen. Springer, Berlin Heidelberg New York Tokio, S 336Google Scholar
  90. Mann DL, Maisel AS, Atwood EJ, Engler RJ, LeWinter MM (1985) Absence of cardioversion-induced ventricular arrhythmias in patients with therapeutic digoxin levels. JACC 5: 882–890PubMedGoogle Scholar
  91. Manning WJ et al. (1993) Cardioversion from atrial fibrillation without prolonged anticoagulation with use of transoesophageal echocardiography to exclude the presence of atrial thrombi. N Engl J Med 328: 750PubMedGoogle Scholar
  92. Marriott HJL (1976) Differential diagnosis of supraventricular and ventricular tachycardia. Geriatrics 25: 91Google Scholar
  93. Mason JW, for the Electrophysiologic Study Versus Electrocardiographic Monitoring Investigators (1993) A comparison of electrophysiologic testing with Holter monitoring to predict anti-arrhythmic drug efficacy for ventricular tachyarrhythmias. N Engl J Med 329: 445–451Google Scholar
  94. Mason JW, Winkle RA (1978) Electrode-catheter arrhythmia induction in the selection and assessment of antiarrhythmic drug therapy for recurrent ventricular tachycardia. Circulation 58: 971–985PubMedGoogle Scholar
  95. McAnulty JH, Rahimtoola SH, Murphy E, De Mots H, Ritzmann LO, Kanarek PE, Kauffman S (1982) Natural history of „high-risk“ bundle-branch block. N Engl J Med 307: 137–143PubMedGoogle Scholar
  96. McClelland JH, Wang X, Beckman KH et al. (1994) Radiofrequency catheter ablation of right atriofascicular (Mahaim) accessory pathways guided by accessory pathway activation potentials. Circulation 89: 2655–2666PubMedGoogle Scholar
  97. McKenna W, Deanfield J, Farnqui A, England D, Oakley C, Goodwin J (1981) Prognosis in hypertrophic cardiomyopathy; role of age and clinical, electrocardiographic and hemodynamic features. Am J Cardiol 47: 532–538PubMedGoogle Scholar
  98. Meinertz T, Hofmann T, Kasper W et al. (1984) Significance of ventricular arrhythmias in idiopathic dilated cardiomyopathy. Am J Cardiol 53: 902–907PubMedGoogle Scholar
  99. Meinertz T, Kasper W, Matthiesen P (1983) Ätiologie kardialer Rhythmusstörungen. In: Luderitz B (Hrsg) Handbuch der inneren Medizin–Herzrhythmusstörungen. Springer, Berlin Heidelberg New York Tokio, S 251–353Google Scholar
  100. Mines GR (1914) On circulating excitations in heart muscles and their possible relation to tachycardia and fibrillation. Trans R Soc Can [Sec IV]: 43–52Google Scholar
  101. Mirowski M, Reid PR, Watkins L, Weisfeld ML, Mower MM (1981) Clinical treatment of life-threatening ventricular tachyarrhythmias with the automatic implantable defibrillator. Am Heart J 102: 265–270PubMedGoogle Scholar
  102. Mitchell LB, Duff HJ, Manyari DE, Wyse DG (1987) A randomized clinical trial of the noninvasive and invasive approaches to drug therapy of ventricular tachycardia. N Engl J Med 317: 1681–1687PubMedGoogle Scholar
  103. Morady F, Sauve MJ, Malone P, Shen EN, Schwartz B, Bhandari A, Keung E et al. (1983) Long-term efficacy and toxicity of highdose amiodarone therapy for ventricular tachycardia or ventricular fibrillation. Am J Cardiol 52: 975–979PubMedGoogle Scholar
  104. Moss AJ et al.and the MADIT Investigators (1996) Improved survival with an implanted defibrillator in patients with coronary disease at high risk for ventricular arrhythmia. N Engl J Med 335: 1933–40Google Scholar
  105. Moss AJ, Davis HT, De Camilla J, Bayer LW (1979) Ventricular ectopic beats and their relation to sudden and non sudden cardiac death after myocardial infarction. Circulation 60: 998–1003PubMedGoogle Scholar
  106. Multicenter Postinfarction Research Group (1983) Risk stratification and survival after myocardial infarction. N Engl J Med 309: 331–336Google Scholar
  107. Murphy D, Murray AM, Robinson BE, Campion EW (1989) Outcomes of cardiopulmonary resuscitation in the elderly. Ann Int Med 111: 199–205PubMedGoogle Scholar
  108. Naumann d’Alnoncourt C (1983) Pathogenese von Herzrhythmusstörungen. In: Luderitz B (Hrsg) Handbuch der inneren Medizin, Herzrhythmusstörungen. Springer, Berlin Heidelberg New York Tokio, S 107–138Google Scholar
  109. Packer M, Bristow Mit, Cohn IN, Colucci WS, Fowler MB, Gilbert EM; Shusterman NH (1996) The effect of carvedilol on morbidity and mortality in patients with chronic heart failure. U.S. Carvedilol Heart Failure Study Group. N Engl J Med 334: 1349–55PubMedGoogle Scholar
  110. Petersen P, Boysen G, Godtfredsen J,Andersen ED,Andersen B (5989) Placebo-controlled, randomized trial of warfarin and aspirin for prevention of thromboembolic compliations in chronic atrial fibrillation: the Copenhagen AFASAK Study. Lancet I: 175–579Google Scholar
  111. Podrid PJ, Schoeneberger A, Lown B (1980) Congestive heartfailu- re caused by oral disopyramide. N Engl J Med 302: 654–657Google Scholar
  112. Roden DM, Lazzara R, Rosen M, Schwartz PJ, Towbin J, Vincent M (1996) Multiple mechanisms in the Long-QT syndrome. Current knowledge, gaps, and future directions. The SADS Foundation Task Force on LQTS. Circulation 94: 1996–2052PubMedGoogle Scholar
  113. Romano C, Gemme C, Pongiglion R (1963) Aritmie cardiache rare dell’età pediatrica. Clin Pediatr 45: 656Google Scholar
  114. Rosenbaum MB, Elizari MV, Lazzari JO (1968) Los hemibloqueos. Paidos, Buenos AiresGoogle Scholar
  115. Rosenberger W, Steinbeck G, Luderitz B (1980) Die Bedeutung der Vorhofstimulation für die Indikation zur Schrittmachertherapie beim Sinusknotensyndrom. Verh Dtsch Ges Inn Med 86: 655–627Google Scholar
  116. Rubin DA, Sorbera C, Cook J, McAllister A, Burke R, Weiss MB (1992) Reversible late potentials due to ischemia. PACE 15: 2250–2254PubMedGoogle Scholar
  117. Ruskin JN, McGovern B, Garan H, DiMarco JP, Kelly E (5983) Anti-arrhythmic drugs: a possible cause of out-of-hospital cardiac arrest. N Engl J Med 309: 1302–1306Google Scholar
  118. Scherlag BJ, Lau SH, Helfant RH, Berkowitz WD, Stein E, Damato AN (5969) Catheter technique for recording His bundle activity in man. Circulation 39: 53–58Google Scholar
  119. Schlepper M (1983) Spezielle Syndrome. In: Luderitz B (Hrsg) Handbuch der inneren Medizin–Herzrhythmusstörungen. Springer, Berlin Heidelberg New York Tokio, S 643–694Google Scholar
  120. Schmidt G, Ulm K, Barthel P, Riemenschneider A, Linzmaier A (5989) 3D-Modell zur Validisierung antiarrhythmischer Effekte. In: Schlepper M (Hrsg) Neue und alte Behandlungsmöglichkeiten bei Herzrhythmusstörungen. Schattauer, Stuttgart New York, S 128Google Scholar
  121. Schwartz PJ (5985) Idiopathic long QT syndrome: progress and questions. Am Heart J 111: 399–411Google Scholar
  122. Schwartz PJ, Moss AJ, Vincent GM, Crampton RS (1993) Diagnostic criteria for the long QT syndrome. An update. Circulation 88: 782–784PubMedGoogle Scholar
  123. Schwartzman D, Demopulos L, Schrem S, Caracciolo E, Perez J, Chinitz L, Slater W (5992) Autonomic manipulation influences both temporal and frequency analyses of late potentials. PACE 15: 220–225Google Scholar
  124. Seipel L (Hrsg) (5978) His-Bündel-Elektrographie und intrakardiale Stimulation. Thieme, StuttgartGoogle Scholar
  125. Seipel L, Pietrek G, Körfer R, Loogen F (1977) Prognose nach Schrittmacherimplantation. Internist 18: 25–24Google Scholar
  126. Sellers TD, Bashore TM, Gallagher JJ (1977) Digitalis in the pre-excitation syndrome. Analysis during atrial fibrillation. Circulation 56: 260–267PubMedGoogle Scholar
  127. Simson MB (5981) Use of signals in the terminal QRS complex to identify patients with ventricular tachycardia after myocardial infarction. Circulation 64: 235–242Google Scholar
  128. Slade AK, Pee S, Jones S, Granle L, Fei L, Camm AJ (1994) New algorithms to increase the initial rate response in a minute volume rate adaptive pacemaker. PACE 17 (11 Pt 2): 1960–1965PubMedGoogle Scholar
  129. SPAF I: Stroke Prevention in Atrial Fibrillation Investigators (1992) Predictors of thromboembolism in atrial fibrillation: I. Clinical features of patients at risk. Ann Intern Med 116: 1–5Google Scholar
  130. SPAF II: The Stroke Prevention in Atrial Fibrillation Investigators (1994) Warfarin versus aspirin for prevention of thromboembolism in atrial fibrillation: Stroke Prevention in Atrial Fibrillation II Study. Lancet 343: 687–691Google Scholar
  131. Steinbeck G (1983) Invasive Verfahren: In: Luderitz B (Hrsg) Handbuch der Inneren Medizin–Herzrhythmusstörungen. Springer, Berlin Heidelberg New York Tokio, S 485–548Google Scholar
  132. Steinbeck G (Hrsg) (1987) Lebensbedrohliche ventrikuläre Herzrhythmusstörungen - Fortschritte in Diagnostik und Therapie. Steinkopff, DarmstadtGoogle Scholar
  133. Steinbeck G, Manz M, Luderitz B (1981) Möglichkeiten und Risiken der programmierten Ventrikelstimulation bei Patienten mit chronisch rezidivierenden Kammertachykardien. Klin Wochenschr 59: 111–121PubMedGoogle Scholar
  134. Steinbeck G, Naumann d’Alnoncourt C, Luderitz B (1983) Treatment of ventricular tachyarrhythmias-pacing. In: Steinbach K et al. (eds) Cardiac Pacing. Steinkopff, Darmstadt, p 779Google Scholar
  135. Steinbigler P, Haberl R, Jeleazcov C et al. (1999) Functional changes of ventricular late potentials by provocation with increase of heart rate: evaluation during atrial pacing. Europace 1 (2): 103–112PubMedGoogle Scholar
  136. Steinbigler P, Haberl R, Moro der E, Steinbeck G (1998) Spätpotentialanalyse im Langzeit-EKG: Anwendung and Grenzen. Herzschrittmachertherapie-und-Elektrophysiologie. 9 (1): 20–25Google Scholar
  137. Steinbigler P, Hamann J, Jilge G, Haberl R, Steinbeck G (1992) Functional changes of late potentials and heart rate variability during acute myocardial ischemia predicts ventricular arrhythmia: a prospective study. Circulation 86/4 (Suppl) I: 2086 (Abstract)Google Scholar
  138. Stoddard MF, Dawkins PR, Prince CR, Ammash NM (1995) Left atrial appendage thrombus is not uncommon in patients with acute atrial fibrillation and a recent embolic event: a transesophageal echocardiographic study. J Am Coll Cardiol 25: 452–459PubMedGoogle Scholar
  139. Strauss HC, Saroff AL, Bigger JT, Giardina EGV (1973) Premature atrial stimulation as a key to the understanding of sinoatrial conduction in man. Circulation 47: 88–93Google Scholar
  140. Tzivoni D, Banai S, Schuger C, Benhorin J, Keren A, Gottlieb S, Stern S (1988) Treatment of torsade de pointes with magnesium sulfate. Circulation 77: 392–397PubMedGoogle Scholar
  141. Vaughan-Williams EM (1970) Classification of antiarrhythmic drugs. In: Sandoe E, Flenstedt-Jensen E, Olsen KH (eds) Symposium on cardiac arrhythmias. Astra, Södertälje, p 449Google Scholar
  142. Velebit V, Podrid P, Lown B, Cohen BH, Grab oys TB (1982) Aggravation and provocation of ventricular arrhythmias by antiarrhythmic drugs. Circulation 65: 886–894PubMedGoogle Scholar
  143. Vincent GM, Timothy KW, Leppert M, Keating M (1992) The spectrum of symptoms and QT intervals in carriers of the gene for the Long-QT syndrome. N Engl J Med 327: 846–852PubMedGoogle Scholar
  144. Ward O (1964) A new familiar cardiac syndrome in children. J Ir Med Assoc 54: 103PubMedGoogle Scholar
  145. Weaver WD, Hill D, Fahrenbruch CE, Copass MK, Martin JS, Cobb LA, Hallstrom AP (1988) Use of the automatic external defibrillator in the management of out-of-hospital cardiac arrest. N Engl J Med 319: 661–666PubMedGoogle Scholar
  146. Wegscheider K, Andresen D, Leitner E-R von, Schröder R (1982) Neue Methode zur Erfassung der Spontanvariabilität einfacher und komplexer Rhythmusstörungen in Abhängigkeit von der Häufigkeit ihres Auftretens. Z Kardiol 71: 179Google Scholar
  147. Weirich J, Antoni H (1990) Differential analysis of the frequency-dependent effects of class I antiarrhythmic drugs according to periodical ligand binding: implications for antiarrhythmic and proarrhythmic efficacy. J Cardiovasc Pharmacol 15: 998–1009PubMedGoogle Scholar
  148. Wellens HJJ (1971) Electrical stimulation of the heart in the study and treatment of tachycardias. Univ Park Press, BaltimoreGoogle Scholar
  149. Wellens HJJ (1986) The electrocardiogram 8o years after Einthoven. JACC 7: 484–491PubMedGoogle Scholar
  150. Wellens HJJ, Bär FW, Lie KI (1978) The value of the electrocardiogram in the differential diagnosis of a tachycardia with a widened QRS complex. Am J Med 64: 27–33PubMedGoogle Scholar
  151. Wit AL, Cranefield PF (1976) Triggered activity in cardiac muscle fibres of the simian mitral valve. Circ Res 38: 85–98PubMedGoogle Scholar
  152. Wolf PA, Abott RD, Kannel WB (1987) Atrial fibrillation: a major contributor to stroke in the elderly. The Framingham Study. Arch Intern Med 147: 1561–1564PubMedGoogle Scholar
  153. Wolff L, Parkinson J, White PD (1930) Bundle branch block with short P-R interval in healthy young people prone to paroxysmal tachycardia. Am Heart J 5: 685–692Google Scholar
  154. Zareba W, Moss AJ, Schwartz PJ, Vincent GM, Robinson JL, Priori SG, Benhorin J; Locati EH, Towbin JA, Keating MT, Lehmann MH, Hall JW (1998) Influence of the genotype on the clinical course of the Long-QT syndrome. N Engl J Med 339: 960–965PubMedGoogle Scholar
  155. Zeiler Arnold A, Mick MJ, Mazurek RP, Loop FD, Trohman RG (1992) Role of prophylactic anticoagulation for direct current cardioversion in patients with atrial fibrillation or atrial flutter. J Am Coll Cardiol 19: 851–855Google Scholar

Copyright information

© Springer-Verlag Berlin Heidelberg 2000

Authors and Affiliations

  • U. Dorwarth
  • A. Gerth
  • R. Haberl
  • E. Hoffmann
  • M. Näbauer
  • C. Reithmann
  • T. Remp
  • G. Steinbeck
  • P. Steinbigler

There are no affiliations available

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