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Myocardial release of lactate, hypoxanthine, and urate during and following percutaneous transluminal coronary angioplasty. Potential mechanism for the generation of free radicals

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Book cover Interventional Cardiology and Angiology

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Abstract

Until recently the assessment of alteration in myocardial metabolism in man early after an abrupt occlusion of a major coronary artery has not been feasible. PTCA however, now provides a unique opportunity to study the time course of these metabolic changes during the transient interruption of coronary flow by the balloon occlusion sequence in patients with single-vessel disease and without angiographically demonstrable collateral circulation (1, 2). The need to detect any persisting metabolic or mechanical dysfunction becomes of even greater concern as the number of dilated vessels and the duration of balloon inflation tend to increase, thereby enhancing both the extent and the severity of ischemia. The risk exists that the damage induced by the intervention may exceed its benefit.

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Author information

Authors and Affiliations

  1. Catheterization and Cardiochemical Laboratories, Thorax Center, Erasmus University, Rotterdam, The Netherlands

    P. W. Serruys, T. Huizer, H. Suryapranata, O. Leborgne & J. de Jong

  2. Department of Cardiology, Catharina Hospital, Eindhoven, The Netherlands

    J. Bonnier & R. Troquay

Authors
  1. P. W. Serruys
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  2. T. Huizer
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  3. J. Bonnier
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  4. R. Troquay
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  5. H. Suryapranata
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  6. O. Leborgne
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  7. J. de Jong
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Editor information

Editors and Affiliations

  1. Medizinische Klinik I, Klinikum Großhadern, Marchioninistraße 15, 8000, München, Germany

    B. Höfling  & A. v. Pölnitz  & 

  2. Medizinische Klinik I, Klinikum Großhadern Universität München, Marchioninistr. 15, 8000, München 70, Germany

    E. Erdmann

  3. Medizinische Klinik I, Univ. Klinikum Großhadern, Marchioninistr. 70, 8000, München 70, Germany

    G. Steinbeck

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© 1989 Springer-Verlag Berlin Heidelberg

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Serruys, P.W. et al. (1989). Myocardial release of lactate, hypoxanthine, and urate during and following percutaneous transluminal coronary angioplasty. Potential mechanism for the generation of free radicals. In: Höfling, B., v. Pölnitz, A., Erdmann, E., Steinbeck, G., Strauer, B.E. (eds) Interventional Cardiology and Angiology. Steinkopff, Heidelberg. https://doi.org/10.1007/978-3-662-12114-6_4

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  • DOI: https://doi.org/10.1007/978-3-662-12114-6_4

  • Publisher Name: Steinkopff, Heidelberg

  • Print ISBN: 978-3-662-12116-0

  • Online ISBN: 978-3-662-12114-6

  • eBook Packages: Springer Book Archive

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