Multiple Dose IP Vancomycin Kinetics during CAPD
Kinetics of vancomycin were studied in five noninfected CAPD patients given repeated IP doses. More than 60% of the first dose was absorbed and absorption from later exchanges was slightly lower. The volume of distribution increased for 18 h but plasma concentrations were maintained by repeated dosing.
KeywordsPeritoneal Dialysis Vancomycin Concentration Dwell Period Intermittent Peritoneal Dialysis Noninfected Patient
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