Influence of Blood Flow and Plasma Proteins on UF Rate in Peritoneal Dialysis
Factors that limit the rate of peritoneal ultrafiltration were evaluated in vivo and by in vitro studies with a hollow fiber dialyzer. With continued ultrafiltration plasma protein concentrations increased, offsetting the osmotic gradient, thereby decreasing the rate of fluid flux. Because the filtration fraction was high, the concentration of protein in the venous end of the capillary reached a point where filtration ceases. The low peritoneal blood flow appeared to limit the ultrafiltration rate.
KeywordsPeritoneal Dialysis Hollow Fiber Limited Blood Flow Filtration Fraction Peritoneal Membrane
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