Hazards of CAPD: Interleukin-1 Production
Evidence has been presented to suggest that the peritoneal macrophage is continuously stimulated during CAPD. Stimulants include pyrogen capable of making the macrophage produce interleukin-1 which in its turn will stimulate prostaglandin and fibroblast formation. Other stimulants exist and remain to be defined. The consequences of this stimulation may well be loss of ultrafiltration followed by sclerosing peritonitis in some cases.
KeywordsCatheter Filtration Europe Lactate Prostaglandin
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