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Hazards of CAPD: Interleukin-1 Production

  • S. Shaldon
  • K. M. Koch
  • E. Quellhorst
  • C. A. Dinarello

Summary

Evidence has been presented to suggest that the peritoneal macrophage is continuously stimulated during CAPD. Stimulants include pyrogen capable of making the macrophage produce interleukin-1 which in its turn will stimulate prostaglandin and fibroblast formation. Other stimulants exist and remain to be defined. The consequences of this stimulation may well be loss of ultrafiltration followed by sclerosing peritonitis in some cases.

Keywords

Peritoneal Dialysis Peritoneal Macrophage Continuous Ambulatory Peritoneal Dialysis Peritoneal Membrane Filter Group 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Springer-Verlag Berlin Heidelberg 1986

Authors and Affiliations

  • S. Shaldon
    • 1
    • 2
    • 3
    • 4
  • K. M. Koch
    • 1
    • 2
    • 3
    • 4
  • E. Quellhorst
    • 1
    • 2
    • 3
    • 4
  • C. A. Dinarello
    • 1
    • 2
    • 3
    • 4
  1. 1.Department of NephrologyUniversity HospitalNimesFrance
  2. 2.Department of NephrologyUniversity HospitalHannoverGermany
  3. 3.Nephrology Center of NiedersachsenHann. MundenGermany
  4. 4.Department of MedicineTufts University School of MedicineBostonUSA

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