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HLA Markers and Peritonitis in CAPD Patients

  • F. Giacchino
  • M. Formica
  • M. Pozzato
  • F. Quarello
  • G. Quattrocchio
  • M. G. Guerra
  • F. Peyretti
  • G. Piccoli

Summary

Peripheral T and B cell subpopulations in 41 CAPD patients and 30 healthy controls were identified using monoclonal anti-T cell antibodies and immunofluorescent staining. HLA typing was also studied. OKT8 reactive cells were significantly higher in patients who had had two or more episodes of peritonitis on follow-up, with no changes from normal in those who did not develop peritonitis. The HLA-B8, DR3 haptotype was more frequent in those who did not develop peritonitis, and since HLA-B8, DR3 is known to be associated with reduced suppressor T cells, such a haplotype may confer resistance to peritonitis.

Keywords

Peritoneal Dialysis Protein Energy Malnutrition Peritonitis Episode CAPD Patient Renal Dialysis Patient 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Springer-Verlag Berlin Heidelberg 1986

Authors and Affiliations

  • F. Giacchino
    • 1
    • 2
  • M. Formica
    • 1
    • 2
  • M. Pozzato
    • 1
    • 2
  • F. Quarello
    • 1
    • 2
  • G. Quattrocchio
    • 1
    • 2
  • M. G. Guerra
    • 1
    • 2
  • F. Peyretti
    • 1
    • 2
  • G. Piccoli
    • 1
    • 2
  1. 1.Medical Nephrology Institute of the University of TurinItaly
  2. 2.Nephrology and Dialysis Departments and Blood BankSan Giovanni HospitalTurinItaly

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