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Visuell evozierte kortikale Potentiale (VEP)

  • Manfred Stöhr
  • Johannes Dichgans
  • Hans-Christoph Diener
  • Ulrich W. Buettner

Zusammenfassung

Visuell evozierte Potentiale sind nach adäquater retinaler Reizung des Auges über dem okzipitalen Cortex abzuleiten. Sie gestatten, allerdings in sehr begrenztem Umfang, eine atraumatische Untersuchung der Physiologie und Pathophysiologic des visuellen Systems. Die Erstbeschreibung der visuell evozierten Potentiale (VEP) muβ man Ruth Cruikshank (1937) zuschreiben, die Veränderungen des α-Rhythmus im EEG bei Ableitung mittels okzipitaler Oberflächenelektroden beschrieb. Sie fand bei Darbietung von Lichtblitzen korrespondierende geringe Ver-änderungen im EEG. Diese Veränderungen waren, gemessen an ihrer Amplitude, kleiner als die Amplitude des α-Rhythmus. Da diese Hchtinduzierten EEG-Antworten nicht mit ausreichender Sicherheit von der übrigen EEG-Aktivität getrennt werden konnten, war eine weitere Untersuchung des Phänomens damals nicht möglich. Erst die Einführung neuer Techniken, wie die der Mittelwertbildung und die schnell anschlieβende Fortentwicklung der automatisierten Auswertung bioelektrischer Signale, machten es möglich, die visuell evozierten Potentiale aus der Grundaktivität des EEG herauszuheben. Die Methoden zur Evozierung visueller Potentiale sowie deren Auswertung wurden in den letzten Jahren mehrfach zusammenfassend beschrieben (Vaughan 1966; Ludlam et al. 1970; MacKay u. Jeffreys 1973; Lazarus 1974a, b; Sokol 1976; Desmedt 1977; Regan 1977; Riggs 1977b; Halliday 1978; Huber 1978; Sherman 1979; Diener 1980).

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Copyright information

© Springer-Verlag Berlin Heidelberg 1982

Authors and Affiliations

  • Manfred Stöhr
    • 1
  • Johannes Dichgans
    • 1
  • Hans-Christoph Diener
    • 1
  • Ulrich W. Buettner
    • 1
  1. 1.Abteilung Allgemeine NeurologieNeurologische KlinikTübingen 1Deutschland

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