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The malic enzymes

1.1.1.38 L-malate:NAD(P) oxidoreductase (decarboxylating) Malate dehydrogenases (decarboxylating)

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Enzyme

Part of the book series: Handbuch der Physiologisch- und Pathologisch-Chemischen Analyse ((1071,volume 6 / a))

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Zusammenfassung

The malic enzyme catalyzes the following reaction:

$$ {\text{L - malate + PN}}^{\text{ + }} \rightleftharpoons {\text{pyruvate + PNH + H}}^{\text{ + }} {\text{ + CO}}_{\text{2}} {\text{.}} $$
((1))

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Abbreviations

DPN and DPNH:

oxidized and reduced diphosphopyridine nucleotide

TPN and TPNH:

oxidized and reduced triphosphopyridine nucleotide

PN and PNH:

oxidized and reduced pyridine nucleotide (without specifying type)

3′ TPN:

the 3′ phosphate analogue of TPN

EDTA:

ethylene diamine tetraacetic acid

pCMB:

p-chloromercuribenzoate

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R. Abraham E. Balke K.-H. Bässler R. K. Bonnichsen H. Breuer T. Bücher F. C. Charalampous L. W. Cunningham G. E. Glock F. Heinz O. Hoffmann-Ostenhof S. Hollmann M. Klingenberg K. Krisch W. Lamprecht K. Lang A. L. Lehninger S. LeonhÄuser K. Leybold S. Liao W. Luh L. Lumper A. C. Maehly H. R. Mahler G. Mohn A. P. Nygaard D. Pette G. Pfleiderer W. J. Rutter K. A. Sack I. Schirrmacher-Göllner G. Siebert E. C. Slater H. Staudinger F. B. Straub H. Süllmann E. Werle J. N. Williams Jr. H. G. Williams-Ashman J. B. Wise

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Rutter, W.J. (1964). The malic enzymes. In: Abraham, R., et al. Enzyme. Handbuch der Physiologisch- und Pathologisch-Chemischen Analyse, vol 6 / a. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-662-11689-0_13

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  • DOI: https://doi.org/10.1007/978-3-662-11689-0_13

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