Effects of preoperative digitalisation on postoperative left heart performance and incidence of complications following hip surgery. First results of a prospective study
The postoperative course may be complicated by cardiac events, especially heart failure. In this study the influence of preoperative digitalisation was investigated on the occurrence of postoperative cardiac complications.
- Group A:
Control (without digitalis; n = 13)
- Group B:
Preoperative digitalisation with 1.0 mg digitoxin and maintenance dosis (MD) of 0.1 mg/die digitoxin (n = 13).
- Group C:
Digitalisation with 0.75 mg and MD of 0.07 mg/die digitoxin (n = 12).
Severe cardiac complications (such as severe heart failure, angina pectoris, tachyarrhythmia) were significantly more frequent in the control group. In 6 patients from this group the need for digitalisation due to heart failure or tachycardia occured.
The STI were prolonged significantly in the nondigitalised patients 7 days postoperatively. This postoperative deterioration of LV performance was prevented by preoperative digitalisation, as demonstrated in the postoperatively unchanged STI in digitalised patients of group B and C.
The dose of digoxin was not significant of either the clinical course or in the alteration of STI.
We conclude from this study that preoperative digitalisation with a low dose of digitoxin may be useful for the reduction of postoperative cardiac risks in elderly patients.
KeywordsFentanyl Glycoside Digoxin Ethrane Digitoxin
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