Marked Cerebrospinal Fluid Collection Associated with Hepatic Failure

  • Takao Enomoto
  • Masanori Hashikawa
  • Tadao Nose
  • Yutaka Maki
  • Kenzo Hamano
  • Norimasa Nakamura

Abstract

We report two cases with abnormal CSF accumulation in the cranium. One case had marked dilatation of the ventricular system, for which a vetriculoperitoneal shunt was carried out. The shunt was not beneficial and it turned out that the patient was suffering from ornithine transcarbamylase deficiency. The second case developed marked subdural effusion after fulminating hepatic failure and septicemia, for which drainage of the subdural space and subsequent insertion of Ommaya reservoirs were carried out. In spite of successful CSF control, the outcome was bad, both cases being incapacitated due to severe encephalopathy probably caused by hyperammonemia. The results of serial computed tomographic follow-up are presented. (Brain Dev 10: 389–392, 1988)

Key words

Ornithine transcarbamylase deficiency Hepatitis Hyperammonemia Brain atrophy Subdural effusion 

Copyright information

© Springer-Verlag Berlin Heidelberg 1990

Authors and Affiliations

  • Takao Enomoto
    • 1
  • Masanori Hashikawa
    • 1
  • Tadao Nose
    • 1
  • Yutaka Maki
    • 1
  • Kenzo Hamano
    • 1
  • Norimasa Nakamura
    • 1
  1. 1.Department of Neurosurgery, Institute of Clinical MedicineUniversity of TsukubaTsukubaJapan

Personalised recommendations