The correlation between catecholamine and lipid peroxidation induced damage in heart cells
Cardiocytes incubated with isoprenaline plasma showed an initial rise in the intracellular ATP levels followed by a steady fall; after two hours the ATP levels of the cells treated with the plasma were less than half that of the control cells. This fall in intracellular ATP was accompanied by morphological changes, in particular the formation of both large and small membrane blebs.
Key wordscatecholamines lipid peroxidation necrosis free radicals sarcolemmal blebbing
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