The correlation between catecholamine and lipid peroxidation induced damage in heart cells

  • A. A. Noronha-Dutra
  • E. M. Steen
  • N. Woolf
Conference paper


Cardiocytes incubated with isoprenaline plasma showed an initial rise in the intracellular ATP levels followed by a steady fall; after two hours the ATP levels of the cells treated with the plasma were less than half that of the control cells. This fall in intracellular ATP was accompanied by morphological changes, in particular the formation of both large and small membrane blebs.

Key words

catecholamines lipid peroxidation necrosis free radicals sarcolemmal blebbing 


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Copyright information

© Springer-Verlag Berlin Heidelberg 1984

Authors and Affiliations

  • A. A. Noronha-Dutra
    • 2
  • E. M. Steen
    • 1
  • N. Woolf
    • 1
  1. 1.The Bland-Sutton Institute of PathologyThe Middlesex Hospital Medical SchoolLondonUK
  2. 2.Bland-Sutton InstituteMiddlesex Hospital Medical SchoolLondonUK

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