Zusammenfassung
Für die Organtransplantation konnten in der BRD im Jahr 2001 mehr als 3800 solide Organe explantiert werden. Der größte Teil der für die Organtransplantation zur Verfügung stehenden Organe stammt von hirntoten Spendern. Der Eintritt des Hirntodes führt zu zahlreichen pathophysiologischen Veränderungen, die eine Beeinträchtigung der Spenderorgane nach sich ziehen. Ohne konsequente Therapie kommt es innerhalb weniger Stunden zum Organversagen und Herzkreislaufstillstand und damit zum Verlust der Spenderorgane. Eine Möglichkeit, die Zahl der Spenderorgane zu erhöhen, bietet die Lebendorganspende ganzer Organe oder Teile von Organen gesunder Spender. Hier steht neben dem Organverlust die Senkung der perioperativen Morbidität und Mortalität des Spenders im Vordergrund.
Der vorliegende Artikel soll im ersten Teil einen Überblick über die anaesthesio-logische Betreuung von Lebendorganspendern geben. Im zweiten Teil werden die mit dem Hirntod einhergehenden pathophysiologischen Veränderungen, die Intensivtherapie und das anaesthesiologische Management während der Organentnahme dargestellt.
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Sinner, B., Graf, B.M. (2003). Anaesthesie zur Organentnahme. In: Bardenheuer, H.J., Forst, H., Rossaint, R., Spahn, D.R. (eds) Weiterbildung für Anästhesisten 2002. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-662-10888-8_6
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