Zusammenfassung
Die Befunde von Landsteiner [25], daß die roten Blutkörperchen (Erythrozyten) mancher Menschen durch die Seren anderer verklumpt (agglutiniert) werden, führten zu Beginn dieses Jahrhunderts zur Entdeckung der ersten Blutgruppen, des ABO-Systems. Während die Antikörper (Anti-A, Anti-B) gegen die A- und B-Antigene natürlicherweise, d. h. ohne offensichtliche antigene Stimulierung, in menschlichen Seren vorkommen (sog. reguläre Antikörper), sofern der Spender des Serums das entsprechende Merkmal nicht aufweist, beruht der Nachweis der meisten anderen Blutgruppeneigenschaften in der Regel auf der Anwendung von Antikörpern, die durch Immunisierung entstanden sind und nicht regelmäßig in menschlichem Serum vorkommen (sog. irreguläre Antikörper).
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Dahr, W. (1988). Blutgruppen von Erythrozyten. In: Mueller-Eckhardt, C. (eds) Transfusionsmedizin. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-662-10601-3_8
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