Zusammenfassung
Die Übertragung von Blut oder Blutbestandteilen ist eine eingreifende ärztliche Maßnahme. Die mit einer Bluttransfusion verbundenen Risiken, wie Infektionsgefährdung, Transfusionsreaktion oder Sensibilisierung, sind gegenüber dem Nutzen einer Transfusionsbehandlung individuell abzuwägen. Die Entscheidung ist einfach zu treffen, wenn eine vitale Indikation, wie Substitution nach schweren Blutverlusten, vorliegt; sie muß bei relativer Indikation, z. B. Transfusionsvorbehandlung potentieller Empfänger von Nierentransplantaten, durch Ergebnisse fundierter Studien gut begründet sein.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
Preview
Unable to display preview. Download preview PDF.
Literatur
Albert ED, Scholz S, Meixner U, Land W (1981) HLA-A, B matching of pretransplant blood transfusion is associated with poor graft survival. Transplant Proc 13:175–177.
Albrechtsen D, Soedal G, Berg KJ, Bondevik H, Brekke JB, Fauchald P, Jakobson A, Opedal BR, Rugstad HE, Thorsby E (1984) Cyclosporine in living related and cadaveric transplantation. Transplant Proc 16:1191–1194.
Alexandre GPJ, van Cangh PJ (1978) Influence of blood transfusion on kidney transplantation. Dial Transplant 7:392–396.
Anderson CB, Tyler JD, Sicard GA, Andermann CK, Rodey GE, Etheredge EE (1985) Renal allograft recipient pretreatment with immunosuppression and donor-specific blood. Transplant Proc 17:1047–1050.
Betuel H, Touraine JL, Malik MC, Traeger J (1981) Pretransplant protocols: Thoracic duct drainage, transfusions programmed and random, their effects on kidney graft survival. Transplant Proc 13:167–171.
Betuel H. Cantarovitch D, Robert F, Gebuhrer L, Touraine JL, Dubernard JM, Traeger J (1985) Platelet transfusions preparative for kidney transplantation. Transplant Proc 17:2235–2337.
Bijnen AB, Heineman E, Marquet RL, Messen GJCM, Obertop H, Tank B, Jeekel J (1984) Lack of beneficial effect of thrombocyte transfusions on kidney graft survival in dogs. Transplantation 37:213–214.
Borleffs JCC, Neuhaus P, van Rood JJ, Balner H (1982) Platelet transfusions improve kidney allograft in rhesus monkeys without inducing cytotoxic antibodies. Lancet 1:1117–1118.
Borleffs JCC, Neuhaus P, van Rood JJ, Balner H (1983) Platelet transfusions have a positive effect on kidney allograft survival in rhesus monkeys and induce virtually no cytotoxic antibodies. Transplant Proc 15:985–987.
Burlingham EJ, Sparks EMF, Sondel PM, Glass NR, Beizer FO, Sollinger HW (1985) Improved renal allograft survival following donorspecific transfusions. Transplantation 39:12–17.
Burrows L, Tartter P (1982) Effect of blood transfusions on colonic malignancy recurrence rate. Lancet 11:662.
Buy-Quang D, Soulillou JP. Fontenaille Ch, Guimbretière Guenel J (1977) Rôle bénéfique des transfusions sanguines et des grossesses dans la survie des allogreffes rénal. Nouv Presse Med 6:3503–3507.
Chapman JR, Fischer M, Ting A, Morris PJ (1985) Platelet transfusion before renal transplantation in humans. Transplant Proc 17:1038–1040.
Clift RA, Beatty PG, Thomas ED, Buckner CD, Weiden P, McGuffin R (1985) Marrow transplantation from mismatched donors for the treatment of malignancy. Transplant Proc 17:445–446.
Dewar PJ, Murray S, Wilkinson R, Elliot RW, Word MK, Proud G, Taylor RMR (1980) A new finding relating to transfusion and renal transplants. Transplantation 29:379–380.
Es van AA, Marquet RL, van Rood JJ, Kalff MW, Balner H (1977) Blood transfusions induce prolonged kidney allograft survival in rhesus monkeys. Lancet 1:506–509.
European Multicentre Trial Group (1983) Cyclosporin in cadaveric renal transplantation: one year follow-up a multicentre trial. Lancet 11:986–989.
Fassbinder W, Frei U, Persijn GG, Bechstein K, Schopow K, Dathe G, Jonas D, Weber W, Kuehnl P, Schoeppe W (1982) Graft survival in renal allograft recipients transfused perioperatively only. Transplant Proc 14:164–167.
Fehrmann I, Ringden O, Ost L, Groth CG (1985) The long term effect of pre-transplant blood transfusions on cadaveric kidney graft and patient survival rates. Transplant Proc 17:1080–1082.
Foster RS jr, Foster JC, Constanza MC (1983) Do blood transfusions have an adverse effect on survival after mastectomy for breast cancer? Proc Amer Soc Clin Oncol 2:60.
Francis DMA, Shenton BK (1981) Blood transfusion and tumor growth:evidence from laboratory animals. Lancet 11:871.
Francis DMA, Shenton BK, Proud G, Taylor RMR (1982) Tumor growth and blood transfusion. J Exp Clin Cancer Res 1:121–126.
Frisk B, Brynger H, Sandberg L (1982) Two random transfusions before primary renal transplantation-four years experience from a single center. Transplant Proc 14:386–388.
Fuller TC, Delmonico FL, Cosimi AB, Huggins CE, King M, Russell PS (1977) Effect of various types of RBC transfusions on HLA immunization and renal allograft survival. Transplant Proc 9:117–119.
Gardner B, Harris KR, Digard NJ, Gosling DC, Campbell MJ, Tate DG, Sharman VL, Slapak M (1985) Do recipients of cadaveric renal allograft on cyclosporine require prior transfusions? Experience of a single unit. Transplant Proc 17:1032–1033.
Glass NR, Miller DT, Sollinger HW, Beizer FO (1985) A four-year experience with donor blood transfusion protocols for living donor renal transplantation. Transplant Proc 17:1023–1025.
Hourmant M, Soulillou JP, Buy-Quang D (1979) Beneficial effect of blood transfusions. Transplantation 28:40–43.
Hunsicker LG, Oei GLS, Freeman RM, Thompson JS, Corry RJ (1979) Effect of blood transfusions on cadaver renal allograft survival. Transplant Proc 11:156–159.
Jamieson SW (1985) Recent developments in heart and heart-lung transplantation. Transplant Proc 17:199–203.
Kahan BD, van Buren CT, Flechner SM, Payne WD, Boileau M, Kerman RH (1983) Cyclosporine immunosuppression mitigates immunologic risk factors in renal allotransplantation. Transplant Proc 15:2469–2478.
Keown PA, Descamps B (1979) Improved renal allograft survival after blood transfusion: A nonspecific erythrocyte-mediated immunoregulatory process? Lancet 1:20–22.
Klingemann HG, Storb R (1985) Allogene Knochenmark-Transplantation. Dtsch Ärzteblatt 24:1852–1861.
Klatzmann D, Gluckman JC, Chapuis F, Foucault C, Metivier F, Rottembourg J (1985) Independent cell-mediated lympholysis and mixed lymphocyte reaction suppression after blood transfusions in human. Transplant Proc 17:1051–1052.
Klintmalm G, Brynger H, Flatmark A, Frödin L, Husberg B, Thorsby E, Groth CG (1985) The blood transfusion, DR matching, and mixed lymphocyte culture effects are not seen in cyclospo-rine-treated renal transplant recipients. Transplant Proc 17:1026–1031.
Land W, Scholz HM, Mempel W, Illner WD, Castro LA, Schödel F (1985) Preliminary experience with cadaveric donor-specific platelet transfusions (CDSPT) prior to kidney transplantation. Neth J Med 28:262–264.
Lenhard V, Schäfer A, Dreikorn K (1982) Bedeutung immunologischer Faktoren für die klinische Nierentransplantation. Nieren- und Hoch-druckkrkh. 11:25–35.
Lenhard V, Seifert P, Maassen G, Grosse-Wilde H, Johannsen R, Geisen HP, Kluge A (1982) Blood transfusion-induced suppression of cellular immunity in prospective kidney recipients. Transplant Proc 14:160–164.
Lenhard V, Maasen G, Grosse-Wilde H, Wernet P, Opelz G (1983) Effect of blood transfusions on immunoregulatory cells in prospective transplant recipients. Transplant Proc 15:1011–1015.
Lenhard V, Renner D, Hansen B, Opelz G (1985) Suppression of antibody response and prolongation of skin survival by multiple blood transfusions in the rat. Transplantation 39:424–429.
Lenhard V, Fassbinder W, Hillebrand G, Persijn GG, Wilms H (1986) Bluttransfusionen und Nierentransplantation. Nieren- und Hochdruckkrkh. 15:73–82.
Maki T, Okazaki H, Wood ML, Monaco AP (1981) Suppressor cells in mice bearing intact skin allograft after blood transfusions. Transplantation 32:463–467.
Marquet RL, Heystek GA, Niessen GJCM, Jeekel J (1982) Induction of suppressor cells by a single blood transfusion in rats. Transplant Proc 14:397–399.
Marquet RL, Heystek GA, Westbroek DL, Jeekel J (1982) Modification of syngeneic tumor growth by allogeneic blood transfusion in the rat. Langen-becks Arch Chir 357:169–170.
Marquet RL, Tank B, Heineman E, Obertop H, Niessen GJCM, Bijnen AB, Westbroeck DL, Jeckel M (1983) Pre-transplant platelet transfusions do not improve kidney graft survival in beagle dogs. Lancet 1:774.
Morris PJ, Thompson JF, Ting A, Wood RF (1984) Is pregraft blood transfusion beneficial in cyclo-sporine-treated renal transplant recipients? Lancet 1:98.
Muller JY, Kaplan C, Betuel H, Bignon JD, Fauchet R, Gluckman JC, Soulillou JP, Thibault Ph (1982) Effet des transfusions sanguines sur les gref-fes de rein. Nouv Presse Med 11:3697–3701.
Nube MJ, Persijn GG, Kalff MW, van Rood JJ (1981) Kidney transplantation — transplant survival after planned HLA-A and -B matched blood transfusions. Tissue Antigens 17:449–454.
Obertop H, Bijnen AB, Vriesendorp HM, West-broek DL (1978) Prolongation of renal allograft survival in DLA tissue-typed beagles after third-party blood transfusions and immunosuppressive treatment. Transplantation 26:255–259.
Oh JH, McCluire HM (1982) Lymphocytotoxic antibodies induced by fresh blood, stored blood and platelets in rhesus monkeys. Transplant Proc 14:410–412.
Opelz G (1981) Transfusions and malignancy. Lancet 11:1057.
Opelz G (1984) Blood transfusion and renal transplantation. In: Morris PJ (ed) Kidney Transplantation — Principles and Practice. Grune and Strat-ton, London pp 323–333.
Opelz G (1985) Current relevance of the transfusion effect in renal transplantation. Transplant Proc 17:1015–1021.
Opelz G, Terasaki PI (1974) Poor kidney transplant survival in recipients with frozen-blood transfusions or no transfusions. Lancet 11:696–698.
Opelz G, Terasaki PI (1976) Prolongation effect of blood transfusions on kidney graft survival. Transplantation 22:380–383.
Opelz G, Terasaki PI (1980) Dominant effect of transfusions on kidney graft survival. Transplantation 29:153–158.
Opelz G, Terasaki PI (1982) International study of histocompatibility in renal transplantation. Transplantation 33:87–95.
Opelz G, Sengar DPS, Mickey MR, Terasaki PI (1973) Effect of blood transfusions on subsequent kidney transplants. Transplant Proc 5:253–259.
Opelz G, Graver B, Mickey MR, Terasaki PI (1982) Lymphocytotoxic antibody responses to transfusions in potential kidney transplant recipients. Transplantation 32:177–183.
Penn I (1979) Tumor incidence in human allograft recipients. Transplant Proc 11:1047–1051.
Penn I, Starzl TE (1972) Malignant tumors arising de novo in immunosuppressed organ transplant recipients. Transplantation 14:407–417.
Persijn GG, Hooff JP, van Kalff MW, Landsbergen Q, van Rood JJ (1977) Effect of blood transfusions and HLA matching on renal transplantation in the Netherlands. Transplant Proc 9:503–505.
Persijn GG, van Leeuwen A, Parlevliet J, Cohen B, Landsbergen Q, d’Amaro J, van Rood JJ (1981) Two major factors influencing kidney graft survival in Eurotransplant: HLA-DR matching and blood transfusion(s). Transplant Proc 13:150–154.
Raftery MJ, Lang CJ, Schwarz G, O’Shea J, Varg-hese Z, Sweny P, Fernando ON, Moorhead JF (1985) Failure of azathioprine to prevent sensiti-sation due to third party transfusion. Transplant Proc 17:1044–1046.
Russell PS (1977) Steps toward immediate progress in clinical transplantation. Transplant Proc 9:1327–1333.
Säfwenberg JG, Backmann-Bave U, Högman CF (1977) The effect of blood transfusions on cadaver kidney transplants — an analysis of patients transplanted in Uppsala. Scand J Urol Nephrol 42:59–61.
Salvatierra O, Vincenti F, Amend W, Potter D, Iwaki Y, Opelz G, Terasaki PI, Duca R, Cochrum KC, Haynes D, Stoney RJ, Feduska NJ (1980) Deliberate donor-specific blood transfusions prior to living related transplantation: A new approach. Ann Surg 192:543–552.
Salvatierra O, Amend W, Vincenti F, Potter D, Iwaki Y, Opelz G, Terasaki PI, Duca R, Haynes D, Cochrum KC, Hopper S, Feduska NJ (1981) Pretreatment with donor-specific blood transfusions in related recipients with high MLC. Transplant Proc 13:142–149.
Singal DP, Joseph S, Ludwin D (1985) Blood transfusions, suppressor cells, and anti-idiotypic antibodies. Transplant Proc 17:1104–1107.
Starzl TE, Iwatsuki S, Shaw BW, Gordon RD (1985) Orthoptic liver transplantation in 1984. Transplant Proc 17:250–258.
Stiller CR, Lockwood BL, Sinclair NR, Ulan RA, Sheppard RR, Sharpe JA, Hayman P (1978) Beneficial effect of operation-day blood transfusions on human renal allograft survival. Lancet 1:169–170.
Suciu-Foca N, Rohowsky C, Kung P, Lewison A, Nicholson J, Reemtsma K, King DW (1983) MHC-specific idiotypes on alloactivated human T cells. In vivo and in vitro studies. Transplant Proc 15:784–789.
Terasaki PI (1984) The beneficial transfusion effect of kidney graft survival attributed to clonal deletion. Transplantation 37:119–125.
Thomas ED (1985) Current status of bone marrow transplantation. Transplant Proc 17:428–431.
Vincenti F, Duca RM, Amend W, Perkins HA, Cochrum KC Feduska NJ, Salvatierra O (1978) Immunologic factors determining survival of cadaver-kidney transplants. N Engl J Med 299:793–798.
Werner-Favre C, Jeannet M, Harder F, Montadon A (1979) Blood transfusions, cytotoxic antibodies, and kidney graft survival. Transplantation 28:343–346.
Williams GM, Ting A, Cullen PR, Morris PJ (1979) Transfusions: Their influence on human renal graft survival. Transplant Proc 11:175–178.
Williams KA, Ting A, French ME, Oliver D, Morris PJ (1980) Peroperative blood transfusions improve cadaveric renal allograft survival in non-transfused recipients. Lancet 1:1104–1106.
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 1988 Springer-Verlag Berlin Heidelberg
About this chapter
Cite this chapter
Lenhard, V., Opelz, G. (1988). Bluttransfusion und Organtransplantation. In: Mueller-Eckhardt, C. (eds) Transfusionsmedizin. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-662-10601-3_25
Download citation
DOI: https://doi.org/10.1007/978-3-662-10601-3_25
Publisher Name: Springer, Berlin, Heidelberg
Print ISBN: 978-3-662-10602-0
Online ISBN: 978-3-662-10601-3
eBook Packages: Springer Book Archive