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Therapie mit Granulozyten

  • J. Neppert

Zusammenfassung

Der Mangel an Granulozyten hat zur Folge, daß pathogene Mikroorganismen im Wirt nicht mehr phagozytiert und/oder abgetötet werden und damit wichtige Voraussetzungen der Entzündung fehlen. Dies ist bereits äußerlich an fehlenden Infiltrationen und Ge-websdemarkierungen bei bakteriellen Absiedlungen in der Haut zu erkennen. Die im Vergleich zu anderen Leukozytenarten sehr zahlreichen Granulozyten phagozytieren größere Mengen fremder Substanzen und Partikel. Hierdurch steht dem Organismus ein Weg der Elimination zur Verfügung, der nicht zwangsläufig immunkompetente Zellen beteiligt wie bei der Antigenpräsentation nach Phagozytose durch langlebige Monozyten/ Makrophagen. Um eine große Phagozytose-kapazität zu erreichen, werden überaus zahlreiche Granulozyten gebildet, die nur kurze Zeit leben.

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© Springer-Verlag Berlin Heidelberg 1988

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  • J. Neppert

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