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Therapie innerer Krankheiten pp 549–566Cite as

Akute Leukämien

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Zusammenfassung

Die akuten Leukämien gehören unbehandelt zu den besonders bösartig verlaufenden Systemerkrankungen. Wesentliche Kennzeichen sind:

  • leukämische Infiltrationen des Knochenmarks, des RES und anderer Organe;

  • mehr oder weniger stark ausgeprägte Ausschwemmung leukämischer Zellen in das periphere Blut, dabei typischer „Hiatus leucaemicus“

  • unreife und schwere Differenzierbarkeit der Leukämiezellen die meistens Kernnukleolen haben;

  • im Knochenmark Verdrängung und Differenzierungsstörung der normalen Leukopoese (Folgen: Resistenzminderung, erhöhte Infektanfälligkeit, schlechte Wundheilung u.a.), der Erythrozytopoese (Anämie) und der Thrombozytopoese (hämorrhagische Diathese).

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Authors
  1. W. Wilmanns
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Editors and Affiliations

  1. Medizinische Klinik II, Klinikum Großhadern, Marchioninistraße 15, D-81377, München, Deutschland

    Gustav Paumgartner

  2. Kastanienallee 14, D-82049, Großhesselohe, Deutschland

    Gerhard Riecker

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© 1995 Springer-Verlag Berlin Heidelberg

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Wilmanns, W. (1995). Akute Leukämien. In: Paumgartner, G., Riecker, G. (eds) Therapie innerer Krankheiten. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-662-10479-8_41

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  • DOI: https://doi.org/10.1007/978-3-662-10479-8_41

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-662-10480-4

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