Akute und chronische respiratorische Insuffizienz

  • D. Walmrath
  • F. Grimminger
  • W. Seeger

Zusammenfassung

Eine respiratorische Insuffizienz bezeichnet den Funktionsverlust des Atmungsapparates (zentrales Atemzentrum, Atemmuskulatur, Lunge), eine ausreichende O2-Aufnahme und Kohlensäureabgabe für den Organismus zu gewährleisten.

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Literatur

  1. 1.
    Amato MBP, Barbas CSV, Medeiros DM, Schettino GPP, Filho GL, Kairalla RA, Deheinzellen D, Morais C, Fernandes EO, Takagaki TV, de Carvalho CR (1995) Beneficial effects of the „open lung approach“ with low distending pressures in acute respiratory distress syndrome: a prospective randomized study on mechanical ventilation. Am J Respir Crit Care Med 1835–1846Google Scholar
  2. 2.
    Amato MBP, Barbas CSV, Medeiros DM, Magaldi RB, Schettino GPP, Filho GL, Kairalla RA, Deheinzellen D, Munoz C, Oliveira R, Takagaki TV, de Carvalho CRR (1998) Effect of a protective ventilation strategy on mortality in the acute respiratory distress syndrome. N Engl J Med 338: 347–354PubMedCrossRefGoogle Scholar
  3. 3.
    Ashbaugh DG, Bigelow DB, Petty TL, Levine BE (1967) Acute Respiratory Distress in Adults. The Lancet II: 319–323Google Scholar
  4. 4.
    Bernard GR, Artigas A, Brigham KL, Carlet J, Falke K, Hudson L, Lamy M, Legall JR, Morris A, Spragg R, and the Consensus Committee (1994) The American-European Consensus conference on ARDS. Am J Respir Crit Care Med 149: 818–824Google Scholar
  5. 5.
    Bone RC, Fisher CJ Jr, Clemmer TP, Slotman GJ, Metz CA, Balk RA, Group the Methylprednisolone Severe Sepsis Study (1987) A Controlled Clinical Trial of High-dose Methylprednisolone in the Treatment of Severe Sepsis and Septic Shock. N Engl J Med 317: 653–658CrossRefGoogle Scholar
  6. 6.
    Bone RC, Fisher CJ Jr, Clemmer TP, Slotman GJ, Metz CA, Balk RA (1989) Sepsis Syndrome: A Valid Clinical Entity. Methylprednisolone Severe Sepsis Study Group. Crit Care Med 17: 389–393PubMedCrossRefGoogle Scholar
  7. 7.
    Bone RC, Slotman G, Maunder R, Silvermann H, Ursprung JJ (1989) Randomized Double-Blind, Multicenter Study of Prostaglandin E, in Patients with the Adult Respiratory Distress Syndrome. Chest 96: 114–119Google Scholar
  8. 8.
    Brochard L, Mancebo J, Wysocki M (1995) Noninvasive ventilation for acute exacerbation of chronic obstructive pulmonary disease. N Engl J Med 333: 817–822PubMedCrossRefGoogle Scholar
  9. 9.
    Brochard L, Roudot-Thoraval F, Collaborative group on VT 25. reduction (1997) Tidal volume reduction in acute respiratory distress syndrome (ARDS): a multicenter randomized study. Am J Respir Crit Care Med 155: A505Google Scholar
  10. 10.
    Driks MR, Craven CE, Cell BR, Manning M, Burke RA, Garvin GM, Kunchas LM, Farber HW, Wedel SA, McCabe WR (1987) Nosocomial pneumonia in intubated patients given 27. sucralfate as compared with antacids or histamine type z blockers. N Engl J Med 317: 1376–1382PubMedCrossRefGoogle Scholar
  11. 11.
    Ely EW, Baker AM, Dunagan DP, Burke HL, Smith AC, Kel- 28. ly PT, Johnson MM, Browder RW, Bowton DL, Haponik EF (1996) Effect on the duration of mechanical ventilation of 29. identifying patients capable of breathing spontaneously. N Engl J Med 335: 1864–1869 30.Google Scholar
  12. 12.
    Farmer JCh, Burkey ThH, Kew RR, Webster RO (1991) Concentration-dependent Regulatory Effects of Prostaglandin E, on Human Neutrophil Function In Vitro. Am Rev Respir Dis 144: 593–599PubMedCrossRefGoogle Scholar
  13. 13.
    Ferguson GT, Gilmartin M (1995) CO, rebreathing during BiPAP ventilatory assistance. Am J Respir Crit Care Med 151: 1126–1135PubMedGoogle Scholar
  14. 14.
    Frikker MJ, Lynch K, Pontoppidan H, Wilson Rs, Rie MA, 32. Zappol WM (1992) The adult respiratory distress syndrome: aetiology, progression and survival. In: Artigas, A, Lemaire, F, Suter, PM, Zapol, WM (eds) Adult Respiratory Distress Syndrome London: Churchill Livingstone: 33: 3–11Google Scholar
  15. 15.
    Frostell C, Fratacci M-D, Wain JC, Jones R, Zapol WM (1991) Inhaled Nitric Oxide. A Selective Pulmonary Vasodilator Reversing Hypoxic Pulmonary Vasoconstriction. 83: 2038–2047Google Scholar
  16. 16.
    Gattinoni L, Pelosi P, Vitale G, Pesenti A, D‘Andrea L, Mascheroni D (1991) Body positive changes redistribute lung computed-tomographie density in patients with acute respiratory failure. Anesthesiol 74: 15–23Google Scholar
  17. 17.
    Gregory TJ, Longmore WJ, Moxley MA, Whitsett JA, Reed CR, Fowler AA, Hudson LD, Maunder RJ, Crim C, Hyers TM (1991) Surfactant chemical composition and biophysical 36. activity in acute respiratory distress syndrome. J Clin Invest 88: 1976–1981PubMedCrossRefGoogle Scholar
  18. 18.
    Gegory TJ, Steinberg KP, Spragg R, Gadek JE, Hyers TM, Longmore WJ, Moxley MA, Cai GZ, Hite SD, Smith RM, Hudson LD, Crim C, Newton P, Mitchell BR, Gold AJ (1997) Bovine surfactant therapy for patients with acute respiratory distress syndrome. Am J Respir Crit Care Med 155: 1309–1315CrossRefGoogle Scholar
  19. 19.
    Grimminger F, Seeger W (1990) Regulation infiammatori- 38. scher Abläufe — Angriffspunkte and Grenzen steroidaler Antiphlogistika. medwelt 41: 951–964Google Scholar
  20. 20.
    Günther A, Siebert C, Schmidt R, Ziegler S, Grimminger F, Yabut M, Temmesfeld B, Walmrath D, Morr H, Seeger W (1996) Surfactant alterations in severe pneumonia, ARDS, 39. and cardiogenic lung edema. Am J Respir Crit Care Med 153: 176–184PubMedCrossRefGoogle Scholar
  21. 21.
    Hack CE, Voerman HJ, Eisele B, Keinecke HO et al. (1992) 40. C,-esterase inhibitor substitution in sepsis. Lancet:339–378Google Scholar
  22. 22.
    Hickling KG, Henderson SJ, Jackson R (1990) Low Mortality Associated with Low Volume Pressure Limited Ventilation with Permissive Hypercapnia in Severe Adult Respira 41. tory Distress Syndrome. Intens Care Med 16: 372–377CrossRefGoogle Scholar
  23. 23.
    Hickling KG, Walsh J, Henderson S, Jackson R (1994) Low mortality rate in adult respiratory distress syndrome using low volume, pressure limited ventilation with permissive hypercapnia: a prospective study. Crit Care Med 22:1568–1578Google Scholar
  24. 24.
    High KM, Snider MT, Richard R, Russell GB et al. (1992) Clinical trials of an intravenous oxygenator in patients with adult respiratory distress syndrome. Anesthesiology 77:856-–863Google Scholar
  25. 25.
    Holcroft JW, Vassar MJ, Weber CJ (1986) Prostaglandin E, and Survival in Patients with the Adult Respiratory Distress Syndrome. Ann Surg 203: 371–378PubMedCrossRefGoogle Scholar
  26. 26.
    Hudson LD (1998) Protective ventilation for patients with acute respiratory distress syndrome. N Engl J Med 338: 385–387PubMedCrossRefGoogle Scholar
  27. 27.
    Inglis TJJ, Sherratt MJ, Sproat LJ, Gibson JS, Hawkey PM (1993) Gastroduodenal dysfunction and bacterial colonisation of the ventilated lung. Lancet 341: 911–913.PubMedCrossRefGoogle Scholar
  28. 28.
    Jenkinson S (1989) Prostaglandin E,: Not the Magic Bullet in ARDS. Chest 96: 1–2PubMedCrossRefGoogle Scholar
  29. 29.
    Langer M, Mascheroni D, Marcolin R, Gattinoni L (1988) The Prone Position in ARDS Patients. Chest 94: 103–107PubMedCrossRefGoogle Scholar
  30. Larocco A, Amundson DE, Wallace MR, Malone JL, Old-field EC (1992) Corticosteroids for Pneumocystis-carinii pneumonia with acute respiratory failure — experience with rescue therapy. Chest 102: 892CrossRefGoogle Scholar
  31. 31.
    Lin M, Yang YF, Chiang HT, Chang MS, Chiang BN, Cheitlin MD (1995) Reappraisal of continous positive airway pressure therapy in acute cardiogenic pulmonary edema. Chest 107: 1379–1386Google Scholar
  32. 32.
    Lofaso F, Brochard L, Touchard D, Hang T, Harf A, Isabey D (1995) Evaluation of carbon dioxide rebreathing during pressure support ventilation with airway managment system (BiPAP) devices. Chest 108: 772–778PubMedCrossRefGoogle Scholar
  33. 33.
    Meduri GU, Belenchia JM, Estes RJ, Wunderink RG, El Torky M, Leeper KV Jr (1991) Fibroproliferative phase of ARDS. Clinical findings and effects of corticosteroids. Chest 100: 943–952PubMedCrossRefGoogle Scholar
  34. 34.
    Morris AH, Wallace CJ, Menlove RL, Clemmer TP et al. (1994) Randomized clinicl trial of pressure controlled inverse ratio ventilation and extracorporeal CO, removal for adult respiratory distress syndrome. Am J Respir Crit Care Med 149: 295–305PubMedCrossRefGoogle Scholar
  35. 35.
    Mustard RA, Bohnen JMA, Rosati C, Schouten D (1991) Pneumonia Complicating Abdominal Sepsis. An Independent Risk for Mortality. Arch Surg 126: 170–175PubMedCrossRefGoogle Scholar
  36. 36.
    National Heart, Lung, and Blood Institute. Extracorporeal Support for Respiratory Insufficiency (1979) In: Diseases, Division of Lung, ed. A Collaborative Study In Response to RFP-NHLI-73–20Google Scholar
  37. 37.
    Nava S, Evangelisti I, Rampulla C, Compagnoni ML, Fracchia C, Rubini F (1997) Human and Financial Costs of Noninvasive Mechanical Ventilation in Patients Affected by COPD and Acute Respiratory Failure. Chest 111: 1631–1638PubMedCrossRefGoogle Scholar
  38. 38.
    Prost J-F, Desché P, Jardin F, Margairaz A (1991) Comparison of the Effects of Intravenous Almitrine and Positive End-expiratory Pressure on Pulmonary Gas Exchange in Adult Respiratory Distress Syndrome. Eur Respir J 4: 683–687PubMedGoogle Scholar
  39. 39.
    Puybasset L, Rouby JJ, Mourgeon E, Stewart TE et al. (1994) Inhaled nitric oxide in acute respiratory failure: dose-response curves. Int Care Med 20: 319–327CrossRefGoogle Scholar
  40. 40.
    Radermacher P, Santak B, Becker H, Falke KJ (1989) Prostaglandin E, and nitroglycerin reduce pulmonary capillary pressure but worsen ventilation-perfusion distributions in patients with adult respiratory distress syndrome. Anesthesiology 70: 601–606PubMedCrossRefGoogle Scholar
  41. 41.
    Radermacher P, Santak B, Wüst HJ, Tarnow J, Falke KJ (1990) Prostacyclin and right ventricular functions in patients with pulmonary hypertension associated with ARDS. Int Care Med 16: 227–232CrossRefGoogle Scholar
  42. 42.
    Reinhart K, Hannemann L, Kuss B. Optimal oxygen delivery in critically ill patients. Intens Care Med 1990 16: 149–155CrossRefGoogle Scholar
  43. 43.
    Reyes A, Roca J, Rodriguez-Roisin R, Torres A, Ussetti P, Wagner PD (1988) Effect of almitrine on ventilation-perfusion distribution in adult respiratory distress syndrome. Am Rev Respir Dis 137: 1062–1067PubMedCrossRefGoogle Scholar
  44. 44.
    Rinaldo JE, Rogers RM (1986) Adult respiratory distress syndrome. N Engl J Med 315: 578–579PubMedCrossRefGoogle Scholar
  45. 45.
    Rossaint R, Lopez S, Falke KJ, Slama K, Pison U, Zapol WM (1993) Inhaled nitric oxide for the adult respiratory distress syndrome. N Engl J Med 328: 399–405PubMedCrossRefGoogle Scholar
  46. 46.
    Russell JA, Ronco JJ, Dodek PM (1990) Physiologic effects and side effects of prostaglandin E, in the adult respiratory distress syndrome. Chest 97: 684–692PubMedCrossRefGoogle Scholar
  47. 47.
    Russell JA, Phang PT (1994) The oxygen delivery/consumption controversy. Approaches to management of the critically ill. Am J Respir Crit Care Med 149: 533–537Google Scholar
  48. 48.
    Schuller D, Mitchell JP, Calandrino FS, Schuster DP (1991) Fluid balance during pulmonary edema. Is fluid gain a marker or a cause of poor outcome? Chest 100: 1068–75PubMedCrossRefGoogle Scholar
  49. 49.
    Seeger W, Neuhof H, Hall J, Roka L (1988) Pulmonary vasoconstrictor response to soluble fibrin in isolated lungs: possible role of thromboxane generation. Circ Res 62: 651–659PubMedCrossRefGoogle Scholar
  50. 50.
    Seidenfeld JJ, Pohl DF, Bell RC, Harris GD, Johanson Jr WG Jr (1986) Incidence, site and outcome of infections in patients with the adult respiratory distress syndrome. Am Rev Respir Dis 134: 12–16PubMedGoogle Scholar
  51. 51.
    Shoemaker WC, Appel PL (1986) Effects of prostaglandin E, in adult respiratory distress syndrome. Surgery 99: 275–282PubMedGoogle Scholar
  52. 52.
    Slotman GJ, Burchard KW, D‘Arezzo A et al. (1988) Ketaconazole prevents acute respiratory failure in critically ill surgical patients. J Trauma 28: 648–654Google Scholar
  53. 53.
    Slutsky AS (1994) Consensus conference on mechanical ventilation January 28–30, 1993 at Northbrook, Illinois, USA. Part I. Intensive Care Med 150: 1722–37Google Scholar
  54. 54.
    Snider GL (1988) ARDS, neutrophils and pentoxifylline. Am Rev Respir Dis 138: 1103–1105CrossRefGoogle Scholar
  55. 55.
    Stewart TE, Meade MO, Cook DJ (1998) Evaluation of a ventilation strategy to prevent barotrauma in patients at high risk for acute respiratory distress syndrome. N Engl J Med 338: 355–361PubMedCrossRefGoogle Scholar
  56. 56.
    Sznajder JI, Wood LDH (1991) Beneficial effects of reducing pulmonary edema in patients with acute hypoxemic respiratory failure. Chest 100: 890–891PubMedCrossRefGoogle Scholar
  57. 57.
    Tuxen DV, Cade JF (1986) Effect of aprotinin in adult respiratory distress syndrome. Anaesth Intensive Care 14: 390–399PubMedGoogle Scholar
  58. 58.
    Van Saene HKF, Stoutenbeek CC, Stoller JK (1992) Selective decontamination of the digestive tract in the intensive care unit: current status and future prospects. Crit Care Med 20: 691–703PubMedCrossRefGoogle Scholar
  59. 59.
    Villar J, Slutsky AS (1989) The incidence of the adult respiratory distress syndrome. Am Rev Respir Dis 140: 814–816PubMedCrossRefGoogle Scholar
  60. 60.
    Vincent JL (1990) The relationship between oxygen demand, oxygen uptake, and oxygen supply. Intens Care Med 16: 145–148CrossRefGoogle Scholar
  61. 61.
    Vincent JL, Roman A, de Backer D, Kahn RJ (1990) Oxygen uptake/supply dependency. Effects of short-term dobutamine infusion. Am Rev Respir Dis 142: 2–7PubMedCrossRefGoogle Scholar
  62. 62.
    Walmrath D, Schneider T, Pilch J, Grimminger F, Seeger W (1993) Aerolised prostacyclin reduces pulmonary artery pressure and improves gas exchange in the adult respiratory distress syndrome (ARDS). Lancet 342: 961–962Google Scholar
  63. 63.
    Walmrath D, Schneider T, Pilch J, Grimminger F, Seeger W (1995) Aerosolized prostacyclin in patients with severe pneumonia in the absence and presence of fibrosis. Am J Respir Crit Care Med 151: 724–730PubMedGoogle Scholar
  64. 64.
    Walmrath D, Schermuly R, Schneider T, Olschewski H, Grimminger F, Seeger W (1996) Direct comparison of inhaled nitric oxide and aerosolized prostacyclin in ARDS. Am J Respir Crit Care Med 153: 991–996PubMedCrossRefGoogle Scholar
  65. 65.
    Walmrath D, Günther A, Ghofrani HA, Schermuly R, Schneider T, Grimminger F, Seeger W (1996) Bronchoscopic surfactant administration in patients with severe adult respiratory distress syndrome (ARDS) and sepsis. Am J Respir Crit Care Med 154: 57–62PubMedCrossRefGoogle Scholar
  66. 66.
    Webster NR, Cohen AT, Nunn JF (1988) Adult respiratory distress syndrome - how many cases in the UK? Anaesthesia 43: 923–926PubMedCrossRefGoogle Scholar
  67. 67.
    Yu M, Tomasa G (1993) A double-blind, prospective, randomized trial of ketaconazole, a thromboxane synthetase inhibitor, in the prophylaxis of the adult respiratory dis-tress syndrome. Crit Care Med 21: 1635–1642PubMedCrossRefGoogle Scholar
  68. 68.
    Zabel P, Schönhärting MM, Wolter DT, Schade OF (1989) Oxpentifylline in edotoxaemia. Lancet 30: 1474–1477CrossRefGoogle Scholar
  69. 69.
    Zapol WM, Riman S, Gillis N, Marletta M, Bosken CH (1994) Nitric oxide and the lung. Am J Respir Crit Care Med 149: 1375–1380PubMedCrossRefGoogle Scholar

Copyright information

© Springer-Verlag Berlin Heidelberg 1999

Authors and Affiliations

  • D. Walmrath
  • F. Grimminger
  • W. Seeger

There are no affiliations available

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