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Allergien, Immunmangel- und Autoaggressionskrankheiten

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Zusammenfassung

Injiziert man Labortieren einen Krankheitserreger, für den sie empfänglich sind, so beobachtet man das Auftreten von Krankheitssymptomen. Im Laufe der Auseinandersetzung des Immunsystems mit dem Keim entwickeln die meisten Tiere einen Schutz; bei einer erneuten Injektion verläuft die Krankheit abgeschwächt oder bleibt ganz aus. Bereits vor 100 Jahren wurde die Beobachtung gemacht, daß einige Tiere, die die erste Injektion symptomlos vertragen hatten, bei der zweiten und dritten Injektion gesteigert reagierten. Für diese Reaktionsweise prägte 1906 der Wiener Pädiater Pirquet den Begriff „Allergie“. Heute verstehen wir unter Allergie „eine spezifische Änderung der Immunitätslage im Sinne einer krankmachenden Überempfindlichkeit”.

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