Abstract
Fungi are ubiquitous in nature where they reside as free living organisms. Virtually all of the fungi that have been implicated in infections reside as saprobes in nature, except for the normal symbionts of humans, Malasezzia furfur and opportunistic species of Candida. While we are constantly exposed to fungi, healthy immunological competent individuals have a high degree of natural resistance against fungi. This depends on the degree of exposure to the fungal pathogen since most infections in the immunologically competent host are subclinical or asymptomatic when they occur. Characteristics that appear to be common among the emerging fungi that have been implicated in the opportunistic mycoses of humans are as follow:
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Trauma precedes appearance of the disease or
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An immunosuppressed state exists in the host.
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Gómez, B.L., Porta, A., Maresca, B. (2004). Heat Shock Response in Pathogenic Fungi. In: Domer, J.E., Kobayashi, G.S. (eds) Human Fungal Pathogens. The Mycota, vol 12. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-662-10380-7_6
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