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Human Fungal Pathogens pp 193–205Cite as

Complement and Its Role in Fungal Diseases

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Part of the book series: The Mycota ((MYCOTA,volume 12))

Abstract

The complement system is a group of proteins that form an important component of both innate and antibody-mediated resistance to microbial infection. Activated in a cascade-like fashion, the complement system elicits a variety of effector mechanisms (Fig. 10.1). Initiation of the cascade can occur via two fundamentally different mechanisms termed the classical and alternative pathways.

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Authors and Affiliations

  1. Department of Microbiology and Immunology, University of Nevada School of Medicine, Reno, Nevada, 89557, USA

    Thomas R. Kozel

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  1. Thomas R. Kozel
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  1. Cratis D. Williams Graduate School, Appalachian State University, Boone, North Carolina, 28607, USA

    Judith E. Domer (Dean of Graduate Studies and Research) (Dean of Graduate Studies and Research)

  2. Department of Medicine, Washington University School of Medicine, Box 8051, 660 South Euclid Avenue, St. Louis, Missouri, 63110, USA

    George S. Kobayashi

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Kozel, T.R. (2004). Complement and Its Role in Fungal Diseases. In: Domer, J.E., Kobayashi, G.S. (eds) Human Fungal Pathogens. The Mycota, vol 12. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-662-10380-7_10

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  • DOI: https://doi.org/10.1007/978-3-662-10380-7_10

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