Abstract
The diversity of fungi that cause disease as well as individual host differences make an understanding of the pathogenesis of human mycoses very difficult. The various fungal etiologic agents have impressive variations in virulence potential, as some are overt pathogens in that they can cause disease in immunologically normal individuals, while others are opportunistic pathogens. Along with the growing number of immunologically compromised individuals, the list of fungi belonging to the opportunistic pathogens continues to grow and even includes such species as Saccharomyces cerevisiae (Clemons et al. 1994). Pathogenesis is further complicated by variability among strains of fungi within a given species. Furthermore, the behavior of a fungus in an individual depends on the immunologic status of that person, the tissue or organ involved, and other ill-defined factors.
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References
Alaei S, Larcher C, Ebenbichler C, Prodinger WM, Jana-tova J, Dierich MP (1993) Isolation and biochemical characterization of the iC3b receptor of Candida albicans. Infect Immun 61:1395–1399
Allen DE, Synderman R, Meadows L, Pinnell SR (1977) Generalized Microsporum audouinii infection and depressed cellular immunity associated with a missing plasma factor required for lymphocyte blastogesis. Am J Med 63:991–1000
Alspaugh JA, Granger DL (1991) Inhibition of Cryptococcus neoformans replication by nitrogen oxides supports the role of these molecules as effectors of macrophage-mediated cytostasis. Infect Immun 59:2291–2296
Anderson J, Cundiff L, Schnars B, Gao M, MacKenzie I, Soil DR (1989) Hypha formation in the white-opaque transition of Candida albicans. Infect Immun 57:458–467
Anderson JM, Soll DR (1987) Unique phenotype of opaque cells in the white-opaque transition of Candida albicans. J Bacteriol 169:5579–5588
Antley PP, Hazen KC (1988) Role of yeast cell growth temperature on Candida albicans virulence in mice. Infect Immun 56:2884–2890
Atkin CL, Neilands JB (1968) Rhodotorulic acid, a dike-topiperazine dihydroxamic acid with growth-factor activity. I. Isolation and characterization. Biochemistry 7:3734–3739
Axelsen NH, Kirkpatrick CH (1973) Simultaneous characterization of free Candida antigens and Candida precipitins in a patient’s serum by means of crossed immunoelectrophoresis with intermediate gel. J Immunol Methods 2:245–249
Baker O, Braude AI (1956) A study of stimuli leading to the production of spherules in coccidioidomycosis. J Lab Clin Med 47:169–181
Bailou C (1976) Structure and biosynthesis of the mannan component of the yeast cell envelope. In: Rose AH, Tempest DW (eds) Advances in microbial physiology. Academic Press, New York, pp 93–158
Barnes JL, Osgood RW, Lee JC, King RD, Stein JH (1983) Host-parasite interactions in the pathogenesis of experimental renal candidiasis. Lab Invest 49:460–467
Beaman L, Holmberg CA (1980a) In vitro response of alveolar macrophages to infection with Coccidioides immitis. Infect Immun 28:594–600
Beaman L, Holmberg CA (1980b) Interaction of nonhuman primate peripheral blood leukocytes and Coccidioides immitis in vitro. Infect Immun 29:1200–1201
Beaman L, Pappagianis D (1985) Fate of Coccidioides immitis arthroconidia in human peripheral blood monocyte cultures in vitro. In: Einstein HE, Catanzaro A (eds) Proc 4th Int Conf Coccidioidomycosis. National Foundation for Infectious Diseases, Washington, pp 170–180
Beaman L, Benjamini E, Pappagianis D (1981) Role of lymphocytes in macrophage-induced killing of Coccidioides immitis in vitro. Infect Immun 34:347–353
Bhattacharjee AK, Kwon-Chung KJ, Glaudemans CPJ (1978) On the structure of the capsular polysaccharide from Cryptococcus neoformans serotype C. Immunochemistry 15:673–679
Bhattacharjee AK, Kwon-Chung KJ, Glaudemans CPJ (1981) Capsular polysaccharides from a parent strain and from a possible, mutant strain of Cryptococcus neoformans serotype A. Carbohydr Res 95:237–248
Bistoni F, Vecchiarelli A, Cenci E, Puccetti P, Marconi P, Cassone A (1986) Evidence for macrophage-mediated protection against lethal Candida albicans infection. Infect Immun 51:668–674
Bistoni F, Verducci G, Perito S, Vecchiarelli A, Puccetti P, Marconi P, Cassone A (1988) Immunomodulation by a low-virulence, agerminative variant of Candida albicans. Further evidence for macrophage activation as one of the effector mechanism of nonspecific anti-infectious protection. J Med Vet Mycol 26:285–299
Bornside GH, Bouis PJ, Cohn I (1968) Hemoglobin and Escherichia coli, a lethal intraperitoneal combination. J Bacteriol 95:1567–1571
Branting C, Sund ML, Linder LE (1989) The influence of Streptococcus mutans on adhesion of Candida albicans to acrylic surfaces in vitro. Arch Oral Biol 34:347–353
Brawner DL, Cutler JE (1984) Variability in expression of a cell surface determinant on Candida albicans as evidenced by an agglutinating monoclonal antibody. Infect Immun 43:966–972
Brawner DL, Cutler JE (1986a) Variability in expression of cell surface antigens of Candida albicans during morphogenesis. Infect Immun 51:337–343
Brawner DL, Cutler JE (1986b) Ultrastructural and biochemical studies of two dynamically expressed cell surface determinants on Candida albicans. Infect Immun 51: 327–336
Brawner DL, Cutler JE (1987) Cell surface and intracellular expression of two Candida albicans antigens during in vitro and in vivo growth. Microb Pathogen 2:249–257
Brawner DL, Cutler JE, Beatty WL (1990) Caveats in the investigation of form-specific molecules of Candida albicans. Infect Immun 58:378–383
Brown LA, Chaffin WL (1981) Differential expression of cytoplasmic proteins during yeast bud and germ tube formation in Candida albicans. Can J Microbiol 27: 580–585
Brummer E, Beaman L, Stevens DA (1985) Killing of endospores, but not arthroconidia, of Coccidioides immitis by immunologically activated polymorphonuclear neutrophils. In: Einstein HE, Catanzaro A (eds) Proc 4th Int Conf Coccidioidomycosis. National Foundation for Infectious Diseases, Washington, pp 210–213
Brummer E, Kurita N, Yosihida S, Nishimura K, Miyaji M (1991) Fungistatic activity of human neutrophils against Histoplasma capsulatum: correlation with phagocytosis. J Infect Dis 164:158–162
Brummer E, Castenada E, Restrepo A (1993) Paracoccidioidomycosis: an update. Clin Microbiol Rev 6: 89–117
Bullen JJ (1981) The significance of iron in infection. Rev Infect Dis 3:1127–1138
Bullen JJ, Rogers HJ, Leigh L (1972) Iron-binding proteins in milk and resistance to Escherichia coli infection in infants. Br Med J 8:69–75
Bullen JJ, Rogers HJ, Griffiths E (1978) Role of iron in bacterial infection. Curr Top Microbiol Immunol 80: 1–35
Bullock WE, Wright SD (1987) Role of the adherence-promoting receptors, CR3, LFA-1, and pl50,95, in binding of Histoplasma capsulatum by human macrophages. J Exp Med 165:195–210
Bulmer GS, Sans MD (1967) Cryptococcus neoformans. II. Phagocytosis by human leukocytes. J Bacteriol 94: 1480–1483
Bulmer GS, Sans MD (1968) Crytococcus neoformans. III. Inhibition of phagocytosis. J Bacteriol 95:5–8
Burges G, Holley HP, Virella G (1983) Circulating immune complexes in patients with Candida albicans infections. Clin Exp Immunol 53:165–174
Burt WR, Underwood AL, Appleton GL (1981) Hydroxa-mic acid from Histoplasma capsulatum that displays growth factor activity. Appl Environ Microbiol 42: 560–563
Calderone RA, Braun PC (1991) Adherence and receptor relationships in Candida albicans. Microbiol Rev 55: 1–20
Cameron ML, Granger DL, Weinberg JB, Kozumbo WJ, Koren HS (1990) Human alveolar and peritoneal macrophages mediate fungistasis independently of L-arginine oxidation to nitrite or nitrate. Am Rev Respir Dis 142:1313–1319
Cannon RD (1986) Isolation of a mycelial mutant of Candida albicans. J Gen Microbiol 132:2405–2407
Capowski EE, Wells JM, Karrer KM (1988) Maintenance of methylation patterns in Tetrahymena thermophila. Gene 74:103–104
Caroline L, Taschdjian CL, Kozinn PJ, Schade AL (1964) Reversal of serum fungistasis by addition of iron. J Invest Dermatol 42:415–419
Casadevall A (1993) Protective antibodies to Cryptococcus neoformans. 2nd Int Conf on Cryptococcus and cryptococcosis, Abstr L20
Casanova M, Gil ML, Cardenoso L, Martinez JP, Sentandreu R (1989) Identification of wall-specific antigens synthesized during germ tube formation by Candida albicans. Infect Immun 57:262–271
Casanova M, Martinez JP, Chaffin WL (1990) Fab fragments from a monoclonal antibody against a germ tube mannoprotein block the yeast-to-mycelium transition in Candida albicans. Infect Immun 58:3810–3812
Casanova M, Martinez JP, Chaffin WL (1991) Identification of germ tube cell wall antigens of Candida albicans. J Med Vet Mycol 29:269–272
Casanova M, Lopez-Ribot JL, Monteagudo C, Llombart-Bosch A, Sentandreu R, Martinez JP (1992) Identification of a 58-kilodalton cell surface fibrinogen-binding mannoprotein from Candida albicans. Infect Immun 60:4221–4229
Cassone A (1989) Cell wall of Candida albicans: Its functions and its impact on the host. Curr Top Med Mycol 3:248–314
Cassone A, Mason RE, Kerridge D (1981) Lysis of growing yeast-from cells of Candida albicans by echinocandin: a cytological study. Sabouraudia 19:97–110
Caticha O, Li Y, Griffin J, Winge D, Odell WD (1993) Characterization of a human chorionic gonadotropin-like protein from Candida albicans. Endocrinology 132:667–673
Chaffin WL, Skudlarek J, Morrow KJ (1988) Variable expression of a surface determinant during proliferation of Candida albicans. Infect Immun 56:302–309
Cherniak R, Reiss E, Turner SH (1982) A galactoxylo-mannan antigen of Cryptococcus neoformans serotype A. Carbohydr Res 103:239–250
Cherniak R, Jones RG, Reiss E (1988) Structure determination of Cryptococcus neoformans serotpe A-variant glucuronoxylomannan by C-N.M.R. spectroscopy. Carbohydr Res 172:113–138
Cherniak R, Morris LC, Anderson BC, Meyer SA (1991) Facilitated isolation, purification, and analysis of glucuronoxylomannan of Cryptococcus neoformans. Infect Immun 59:59–64
Clemons KV, McCusker JH, Davis RW, Stevens DA (1994) Comparative pathogenesis of clinical and nonclinical isolates of Saccharomyces cerevisiae. J Infect Dis 169:859–867
Cowart RE, Foster BG (1985) Differential effects of iron on the growth of Listeria monocytogenes: minimum requirements and mechanism of acquisition. J Bacteriol 142:581–587
Cox RA (1989) Coccidioidomycosis. In: Cox RA (ed) Immunology of fungal diseases. CRC Press, Boca Raton, pp 165–197
Cox RA (1993) Coccidioidomycosis. In: Murphy JW, Friedman H, Bendinelli M (eds) Infectious agents and pathogenesis: fungal infections and immune responses. Plenum Press, New York, pp 173–212
Critchley IA, Douglas LJ (1987a) Isolation and partial characterization of an adhesin from Candida albicans. J Gen Microbiol 133:629–636
Critchley IA, Douglas LJ (1987b) Role of glycosides as epithelial cell receptors for Candida albicans. J Gen Microbiol 133:637–643
Cutler JE (1991) Putative virulence factors of Candida albicans. Annu Rev Microbiol 45:187–218
Cutler JE, Kanbe T (1993) Antigenic variability of Candida albicans cell surface. Curr Top Med Mycol 5:27–47
Cutler JE, Brawner DL, Hazen KC, Jutila MA (1990) Characteristics of Candida albicans adherence to mouse tissue. Infect Immun 58:1902–1908
De Bernardis F, Adriani D, Lroenzini R, Pontieri E, Carruba G, Cassone A (1993) Filamentous growth and elevated vaginopathic potential of a nongerminative variant of Candida albicans expressing low virulence in systemic infection. Infect Immun 61:1500–1508
Devi SJN, Schneerson R, Egan W, Ulrich TJ, Bryla D, Robbins JB, Bennett JE (1991) Cryptococcus neoformans serotype A glucuronoxylomannan-protein conjugate vaccines: synthesis, characterization, and immunogenicity. Infect Immun 59:3700–3707
Djaczenko W, Cassone A (1971) Visualization of new ultrastructural components in the cell wall of Candida albicans with fixatives containing TAPO. J Cell Biol 52:186–190
Domer J, Elkins K, Ennist D, Baker P (1988) Modulation of immune responses by surface polysaccharides of Candida albicans. Rev Infect Dis 10:S419–S422
Domer JE (1971) Monosaccharide and chitin content of cell walls of Histoplasma capsulatum and Blastomyces dermatitidis. J Bacteriol 107:870–877
Domer JE (1989) Candida cell wall mannan: a polysaccharide with diverse immunologic properties. CRC Crit Rev Microbiol 17:33–51
Domer JE, Ganer RE (1989) Immunomodulation in response to Candida. In: Immunology series. M Dekker, New York, pp 293–317
Domer JE, Moser SA (1980) Histoplasmosis — a review. Rev Med Vet Mycol 15:159–182
Domer JE, Hamilton JG, Harkin JC (1967) Comparative study of the cell walls of the yeast-like and mycelial phases of Histoplasma capsulatum. J Bacteriol 94: 466–474
Domer JE, Murphy JW, Deepe GS, Franco M (1992) Immunomodulation in the mycoses. J Med Vet Mycol 30(Suppl 1): 157–166
Douglas LJ (1987) Adhesion of Candida species to epithelial surfaces. CRC Crt Rev Microbiol 15:27–43
Douglas LJ, Houston JG, McCourtie J (1981) Adherence of Candida albicans to human buccal epithelial cells after growth on different carbon sources. FEMS Microbiol Lett 12:241–243
Dromer F, Charreire J (1991) Improved amphotericin B activity by a monoclonal anti-Cryptococcus neoformans antibody: study during murine cryptococcosis and mechanisms of action. J Infect Dis 163:1114–1120
Dromer F, Charreire J, Contrepois A, Carbon C, Yeni P (1987) Protection of mice against experimental cryptococcosis by anü-Cryptococcus neoformans monoclonal antibody. Infect Immun 55:749–752
Drutz DJ, Frey CL (1985) Intracellular and extracellular defenses of human phagocytes against Blastomyces dermatitidis conidia and yeasts. J Lab Clin Med 105: 737–750
Drutz DJ, Huppert M (1983) Coccidioidomycosis: factors affecting the host-parasite interaction. J Infect Dis 147: 372–390
Dykstra MA, Friedman L, Murphy JW (1977) Capsule size of Cryptococcus neoformans: control and relationship to virulence. Infect Immun 16:129–135
Edwards JE, Gaither TA, O’shea JJ, Rotrosen D, Lawley TJ, Wright SA, Frank MM, Green I (1986) Expression of specific binding sites on Candida with functional and antigenic characteristics of human complement receptors. J Immunol 137:3577–3583
Eigentler A, Schulz TF, Larcher C, Breitwieser E-M, Myones BL, Petzer AL, Dierich MF (1989) C3bi-binding protein on Candida albicans: temperature-dependent expression and relationship to human complement receptor type 3. Infect Immun 57:616–622
Eisenhauer PB, Lehrer RI (1992) Mouse neutrophils lack defensins. Infect Immun 60:3446–3447
Eissenberg LG, Goldman WE (1991) Histoplasma variation and adaptive strategies for parasitism: new perspectives on histoplasmosis. Clin Microbiol Rev 4:411–421
Eissenberg LG, Goldman WE (1994) The interplay between Histoplasma capsulatum and its host cells. Bailliere’s Clin Infect Dis 1:265–283
Eissenberg LG, West JL, Woods JP, Goldman WE (1991) Infection of P388D1 macrophages and respiratory epithelial cells by Histoplasma capsulatum: selection of avirulent variants and their potential role in persistent histoplasmosis. Infect Immun 59:1639–1646
Eissenberg LG, Goldman WE, Schlesinger PH (1993) Histoplasma capsulatum modulates the acidification of phagolysosomes. J Exp Med 177:1605–1611
Emery T (1971) Role of ferrichrome as a ferric ionophore in Ustilago sphaerogena. Biochemistry 10:1483–1488
Esterly NB, Brammer SR, Crounse RG (1967) The relationship of transferrin and iron to serum inhibition of Candida albicans. J Invest Dermatol 49:437–442
Feigin DS (1983) Pulmonary cryptococcosis: radiologie-pathologie correlates of its three forms. AJR 141: 1263–1272
Fletcher J, Huehns ER (1968) Function of transferrin. Nature 218:1211–1214
Frey CL, Drutz DJ (1986) Influence of fungal surface components on the interaction of Coccidioides immitis with polymorphonuclear neutrophils. J Infect Dis 153: 933–943
Frost GE, Rosenburg H (1973) The inducible citrate-dependent iron transport system in Escherichia coli K12. Biochim Biophys Acta 330:90–101
Fruit J, Cailliez JC, Odds FC, Poulain D (1990) Expression of an epitope by surface glycoproteins of Candida albicans. Variability among species, strains and yeast cells of the genus Candida. J Med Vet Mycol 28:241–252
Galgiani JN (1986) Inhibition of different phases of Coccidioides immitis by human neutrophils or hydrogen peroxide. J Infect Dis 153:217–222
Garzon S, Marquis G, Montplaisir S et al. (1989) Antigenic structure of Candida albicans: electron microscope localization of polysaccharide and immunodeterminants in the cell wall. In: Kurstack E (ed) Immunology of Fungal Diseases. Marcel Dekker, New York, pp 3–36
George BS, Plunkett OA (1948) Dissociation in Candida albicans. J Invest Dermatol 10:327–442
Ghannoum MA, Burns GR, Elteen KA, Radwan SS (1986) Experimental evidence for the role of lipids in adherence of Candida spp. to human buccal epithelial cells. Infect Immun 54:189–193
Gilmore BJ, Retsinas EM, Lorenz JS, Hostetter MK (1988) An iC3b receptor on Candida albicans: structure, function, and correlates for pathogenicity. J Infect Dis 157:38–46
Goihman-Yahr M, Essenfeld-Yahr E, de Albornoz MC, Yarzabal L, de Gomez MH, San Marin B, Ocanto A, Gil F, Convit J (1980) Defect of in vitro digestive ability of polymorphonuclear leukocytes in paracoccidioidomycosis. Infect Immun 28:557–566
Granger DL, Perfect JR, Durack DT (1985) Virulence of Cryptococcus neoformans regulation of capsule synthesis by carbon dioxide. J Clin Invest 76:508–516
Granger DL, Hibbs JB, Perfect JR, Durack DT (1988) Specific amino acid (L-arginine) requirement for the microbiostatic activity of murine macrophages. J Clin Invest 81:1129–1136
Graybill JR (1992) Future directions of antifungal chemotherapy. Clin Infect Dis 14(Suppl 1):S170-S181
Green I, Kirkpatrick CH, Dale DC (1971) Lactoferrin-specific localization in the nuclei of human polymorphonuclear neutrophilic leukocytes. Proc Exp Biol Med 137:1311–1317
Gustafson KS, Vercellotti GM, Bendel CM, Hostetter MK (1991) Molecular mimicry in Candida albicans: role of an integrin analogue in adhesion of the yeast to human endothelium. J Clin Invest 87:1896–1902
Han Y, Lupan DM (1992) Utilization of ferroprotein by Candida albicans during candidastasis by transferrin. Am Soc Microbiol, Annu Meet, Abstr F107
Han Y, van Rooijen N, Cutler JE (1993) Binding of Candida albicans yeast cells to mouse popliteal lymph node tissue is mediated by macrophages. Infect Immun 61:3244–3249
Hazen BW, Hazen KC (1988) Dynamic expression of cell surface hydrophobicity during initial yeast cell growth and before germ tube formation of Candida albicans. Infect Immun 56:2521–2525
Hazen KC (1989) Participation of yeast cell surface hydrophobicity in adherence of Candida albicans to human epithelial cells. Infect Immun 57:1894–1900
Hazen KC (1990) Cell surface hydrophobicity of medically important fungi, especially Candida species. In: Doyle RJ, Rosenberg M (eds) Microbial cell surface hydrophobicity. American Society for Microbiology, Washington, pp 249–295
Hazen KC, Cutler JE (1979) Autoregulation of germ tube formation by Candida albicans. Infect Immun 24:661–666
Hazen KC, Cutler JE (1983a) Isolation and purification of morphogenic autoregulatory substance produced by Candida albicans. J Biochem 94:777–783
Hazen KC, Cutler JE (1983b) Effects of cobalt and morphogenic autoregulatory substance (MARS) on morphogenesis of Candida albicans. Exp Mycol 7:182–187
Hazen KC, Glee PM (1994) Hydrophobic cell wall protein glycosylation by the pathogenic fungus Candida albicans. Can J Microbiol 40:266–272
Hazen KC, Hazen BW (1987) Temperature-modulated physiological characteristics of Candida albicans. Microbiol Immunol 31:497–508
Hazen KC, Hazen BW (1992) Hydrophobic surface protein masking by the opportunistic fungal pathogen Candida albicans. Infect Immun 60:1499–1508
Hazen KC, Hazen BW (1993) Surface hydrophobic and hydrophilic protein alteration in Candida albicans. FEMS Microbiol Lett 107:83–88
Hazen KC, Lay JG, Hazen BW, Fu RC, Murthy S (1990) Partial biochemical characterization of cell surface hydrophobicity and hydrophilicity of Candida albicans. Infect Immun 58:3469–3476
Hazen KC, Brawner DL, Riesselman MH, Jutila MA, Cutler JE (1991) Differential adherence between hydrophobic and hydrophilic yeast cells of Candida albicans. Infect Immun 59:907–912
Heidenreich F, Dierich MP (1985) Candida albicans and Candidastellatoidea, in contrast to other Candida species, bind iC3b and C3d but not C3b. Infect Immun 50: 598–600
Ho YM, Ng MH, Huang CT (1979) Antibodies to germinating and yeast cells of Candida albicans in human rabbit sera. J Clin Pathol 32:399–405
Hogan LH, Klein BS (1994) Altered expression of surface a-l,3-glucan in genetically-related strains of Blastomyces dermatitidis that differ in virulence. Infect Immun 62: 3543–3546
Holzberg M, Artis WM (1983) Hydroxamate siderophore production by opportunistic and systemic fungal pathogens. Infect Immun 40:1134–1139
Houston JG, Douglas LJ (1989) Interaction of Candida albicans with neutrophils: effect of phenotypic changes in yeast cell-surface composition. J Gen Microbiol 135: 1885–1893
Howard DH (1959) Observations on tissue cultures of mouse peritoneal exudates inoculated with Histoplasma capsulatum. J Bacteriol 78:69–78
Howard DH (1960) Effect of mycostatin and fungizone on the growth of Histoplasma capsulatum in tissue culture. J Bacteriol 79:442–449
Howard DH (1964) Intracellular behavior of Histoplasma capsulatum. J Bacteriol 87:33–38
Howard DH (1965) Intracellular growth of Histoplasma capsulatum. J Bacteriol 89:518–523
Howard DH (1973) Further studies on the inhibition of Histoplasma capsulatum within macrophages from immunized animals. Infect Immun 8:577–581
Ismail A, Bedell GW, Lupan DM (1985) Siderophore production by the pathogenic yeast, Candida albicans. Biochem Biophys Res Commun 130:885–891
Jakab E, Paulsson M, Ascencio F, Ljungh A (1993) Expression of vitronectin and fibronectin binding by Candida albicans yeast cells. APMIS 101:187–193
James PG, Cherniak R (1992) Galactoxylomannans of Cryptococcus neoformans. Infect Immun 60:1084–1088
Kagaya K, Miyakawa Y, Fujihara H, Suzuki M, Soe G, Fukazawa Y (1989) Immunological significance of diverse specificity of monoclonal antibodies against mannans of Candida albicans. J Immunol 143:3353–3358
Kahn FW, Jones JM (1986) Latex agglutination tests for detection of Candida antigens in sera of patients with invasive candidiasis. J Infect Dis 153:579–585
Kanbe T, Cutler JE (1994) Evidence for adhesin activity in the acid-stable moiety of the phosphomannoprotein cell wall complex of Candida albicans. Infect Immun 62: 1662–1668
Kanbe T, Li RK, Wadsworth E, Calderone RA, Culter JE (1991) Evidence for expression of C3d receptor of Candida albicans in vitro and in vivo by immunofluorescence and immunoelectron microscopy. Infect Immun 59:1832–1838
Kanbe T, Han Y, Redgrave B, Riesselman MH, Cutler JE (1993) Evidence that mannans of Candida albicans are responsible for adherence of yeast forms to spleen and lymph node tissue. Infect Immun 61:2578–2584
Kanetsuna F, Carbonell LM, Gil F, Azuma I (1974) Chemical and ultrastructural studies on the cell walls of the yeast and mycelial forms of Histoplasma capsulatum. Mycopathologia 54:1–13
Kashino SS, Calich VLG, Burger E, Singer-Vermes LM (1985) In vivo and in vitro characteristics of six Paracoccidioides brasiliensis strains. Mycopathologia 92:173–178
Kashino SS, Singer-Vermes LM, Calich VLG, Burger E (1990) Alterations in the pathogenicity of one Paracoccidioides brasiliensis isolate do not correlative with its in vitro growth. Mycopathologia 111:173–180
Kennedy MJ, Rogers AL, Hanseimen LR, Soll DR, Yancey RJ (1988) Variation in adhesion and cell surface hydrophobicity in Candida albicans white and opaque pheno-types. Mycopathologia 102:149–156
Kennedy MJ, Rogers AL, Yancey RJ (1989) Environmental alteration and phenotypic regulation of Candida albicans adhesion to plastic. Infect Immun 57:3876–3881
Kersulyte D, Woods JP, Keath EJ, Goldman WE, Berg DE (1992) Diversity among clinical isolates of Histoplasma capsulatum detected by polymerase chain reaction with arbitrary primers. J Bacteriol 174:7075–7079
Kimberlin CL, Hariri AR, Hempell HO, Goodman NL (1981) Interactions between Histoplasma capsulatum and macrophages from normal and treated mice: comparison of the mycelial and yeast phases in alveolar and peritoneal macrophages. Infect Immun 34:6–10
Kirsch DR, Kelly R, Kurtz MB (1990) The genetics of Candida. CRC Press, Boca Raton
Klein BS, Hogan LH, Jones JM (1993) Immunologic recognition of a 25-amino acid repeat arrayed in tandem on a major antigen of Blastomyces dermatitidis. J Clin Invest 92:330–337
Klein BS, Chaturvedi S, Hogan LH, Jones JM, Newman SL (1994) Altered expression of surface protein WI-1 in genetically related strains of Blastomyces dermatitidis that differ in virulence regulates recognition of yeasts by human macrophages. Infect Immun 62:3536–3542
Klimpel KR, Goldman WE (1987) Isolation and characterization of spontaneous avirulent variants of Histoplasma capsulatum. Infect Immun 55:528–533
Klimpel KR, Goldman WE (1988) Cell walls from avirulent variants of Histoplasma capsulatum lack alpha-(1,3)-glucan. Infect Immun 56:2997–3000
Klotz SA (1990) Adherence of Candida albicans to components of the subendothelial extracellular matrix. FEMS Microbiol Lett 68:249–254
Klotz SA (1992) Fungal adherence to the vascular compartment: a critical step in the pathogenesis of disseminated candidiasis. Clin Infect Dis 14:340–347
Klotz SA, Penn RL (1987) Multiple mechanisms may contribute to the adherence of Candida yeasts to living cells. Curr Opin Immunol 16:119–122
Klotz SA, Smith RL (1991) A fibronectin receptor on Candida albicans mediates adherence of the fungus to extracellular matrix. J Infect Dis 163:604–609
Klotz SA, Drutz DJ, Zajic JE (1985) Factors governing adherences of Candida species to plastic surfaces. Infect Immun 50:97–101
Klotz SA, Rutten MJ, Smith RL, Babcock SR, Cunningham MD (1993) Adherence of Candida albicans to immobilized extracellular matrix proteins is mediated by calcium-dependent surface glycoproteins. Microb Pathogenesis 14:133–147
Kobayashi H, Shibata N, Nakada M, Chaki S, Mizugami K, Ohkubo Y, Suzuki S (1990) Structural study of cell wall phosphomannan of Candida albicans NIH B-792 (serotype B) strain, with special reference to *H and 13C NMR analyses of acid-labile oligomannosyl residues. Arch Biochem Biophys 278:195–204
Kobayashi H, Shibata N, Suzuki S (1992) Evidence for oligomannosyl residues containing both ß-\,2 and a-1,2 linkages as a serotype A-specific epitope(s) in mannans in Candida albicans. Infect Immun 60:2106–2109
Kolotila MP, Diamond RD (1990) Effects of neutrophils and in vitro oxidants on survival and phenotypic switching of Candida albicans WO-1. Infect Immun 58: 1174–1179
Kozel TR (1993) Cryptococcosis. In: Murphy JW, Friedman H, Bendinelli M (eds) Infectious agents and pathogenesis: fungal infections and immune responses. Plenum Press, New York, pp 277–302
Kurtz MB, Kirsch DR, Kelly R (1988) The molecular genetics of Candida albicans. Microbiol Sci 5:58–63
Kwon-Chung KJ, Bennett JE (1992) Medical mycology. Lea & Febiger, Philadelphia
Kwon-Chung KJ, Weeks RJ, Larsh HW (1974) Studies on Emmonsiella capsulata (Histoplasma capsulatum). Am J Epidemiol 99:44–49
Kwon-Chung KJ, Bennett JE, Rhodes JC (1982a) Taxonomic studies on Filobasidiella species and their an-amorphs. Antonie van Leeuwenhoek 48:25–38
Kwon-Chung KJ, Polacheck I, Popkin TJ (1982b) Melanin-lacking mutants of Cryptococcus neoformans and their virulence for mice. J Bacteriol 150:1414–1421
Kwon-Chung KJ, Bartlett MS, Wheat LJ (1984) Distribution of the two mating types among Histoplasma capsulatum isolates obtained from an urban histoplasmosis outbreak. Sabouraudia. J Med Vet Mycol 22:155–157
Kwon-Chung KJ, Wickes BL, Stockman L, Roberts GD, Ellis D, Howard DH (1992) Virulence, serotype, and molecular characteristics of environmental strains of Cryptococcus neoformans var. gattii. Infect Immun 60:1869–1874
Lahesmaa R, Skurnik M, Vaara M, Leirisalo-Repo M, Nissila M, Granfors K, Toivanen P (1991) Molecular mimickry between HLA B27 and Yersinia, Salmonella, Shigella and Klebsiella within the same region of HLA α1helix. Clin Exp Immunol 86:399–404
Lee KL, Buckley HR, Campbell CC (1975) An amino acid liquid synthetic medium for the development of mycelial and yeast forms of Candida albicans. Sabouraudia 13: 148–153
Leeming JP, Notman FH (1987) Improved methods for isolation and enumeration of Malassezia furfur from human skin. J Clin Microbiol 25:2017–2019
Lehman PF, Reiss E (1980) Comparison of serum anti-Candida albicans mannan IgG levels in ELISA tests of a normal population and diseased patients. Myco-pathologia 70:89–93
Lehrer N, Segal E, Lis H, Gov Y (1988) Effect of Candida albicans cell wall components on the adhesion of the fungus to human and murine vaginal mucosa. Myco-pathologia 102:115–121
Lehrer RI, Ganz T, Selsted ME (1991) Defensins: endogenous antibiotic peptides of animal cells. Cell 64: 229–230
Lew MA (1989) Diagnosis of systemic Candida infections. Annu Rev Med 40:87–97
Li RK, Cutler JE (1993) Chemical definition of an epitope/ adhesin molecule on Candida albicans. J Biol Chem 268:18293–18299
Linehan L, Wadsworth E, Calderone R (1988) Candida albicans C3d receptor, isolated by using a monoclonal antibody. Infect Immun 56:1981–1986
Lonnerdal B, Forsum E, Hambraeus L (1976) A longitudinal study of the protein, nitrogen, and lactose contents of human milk from Swedish well-nourished mothers. Am J Clin Nutr 29:1127–1133
Loose DS, Stover EP, Restrepo A, Stevens DA, Feldman D (1983) Estradiol binds to a receptor-like cytosol binding protein and initiates a biological response in Paracoccidioides brasiliensis. Proc Natl Acad Sci USA 80: 7659–7663
Lorincz AL, Sun SH (1963) Dermatophyte viability at modestly raised temperatures. Arch Dermatol 88:87–96
Lorincz AL, Priestley JO, Jacobs PH (1958) Evidence for a humoral mechanism which prevents growth of dermatophytes. J Invest Dermatol 31:15–17
Louria DB, Kaminski T (1965) Passively-acquired immunity in experimental cryptococcosis. Sabouraudia 4: 80–84
Malloy PJ, Zhao X, Madani ND, Feldman D (1993) Cloning and expression of the gene from Candida albicans that encodes a high-affinity corticosteriod-binding protein. Proc Natl Acad Sci USA 90:1902–1906
Manning M, Mitchell TG (1980) Morphogenesis of Candida albicans and cytoplasmic proteins associated with differences in morphology, strain, or temperature. J Bacteriol 144:258–273
Marcantonio EE, Hynes RO (1988) Antibodies to the conserved cytoplasmic domain of the integrin Bl subunit react with proteins in vertebrates, invertebrates, and fungi. J Cell Biol 106:1765–1772
Maresca B, Kobayashi GS (1989) Dimorphism in Histoplasma capsulatum: a model for the study of cell differentiation in pathogenic fungi. Microbiol Rev 53: 186–209
Marrie TJ, Costerton JW (1981) The ultrastructure of Candida albicans infections. Can J Microbiol 27: 1156–1164
Masson PJ, Heremans JF (1971) Lactoferrin in milk from different species. Comp Biochem Physiol 39B:119–129
Masson PJ, Heremans JF, Dive CH (1966) An iron-binding protein common to many external secretions. Clin Chim Acta 14:729–734
Mattia E, Carruba G, Angiolella L, Cassone A (1982) Induction of germ tube formation by N-acetyl-D-glucosamine in Candida albicans: uptake of inducer and germinative response. J Bateriol 152:555–562
Matzanke BF, Bill E, Trautwein AX, Winkelmann G (1987) Role of siderophores in iron storage in spores of Neurospora crassa and Aspergillus ochraceus. J Bacteriol 169:5873–5876
McCourtie J, Douglas LJ (1981) Relationship between cell surface composition of Candida albicans and adherence to acrylic after growth on different carbon sources. Infect Immun 32:1234–1241
McCourtie J, Douglas LJ (1985) Extracellular polymer of Cardida albicans: isolation, analysis and role in adhesion. J Gen Microbiol 131:495–503
McEwen J, Brummer E, Stevens DA, Restrepo A (1987a) Effect of PMN and lymphocytes on the yeast form of P. brasiliensis. J Trop Med Hyg 36:603–608
McEwen JG, Salazar ME, Restrepo A (1987b) Susceptibility of P. brasiliensis conidia to products of oxidative metabolism. Exp Mycol 11:241–244
Meckstroth KL, Reiss E, Keller JW, Kaufman L (1981) Detection of antibodies and antigenemia in leukemic patients with candidiasis by enzyme-linked immunosorbent assay. J Infect Dis 144:24–32
Medoff G, Sacco M, Maresca B, Schlessinger D, Painter A, Kobayashi GS, Carratu L (1986) Irreversible block of the mycelial-to-yeast phase transition of Histoplasma capsulatum. Science 231:476–479
Medoff G, Kobayashi GS, Painter A, Travis S (1987) Morphogenesis and pathogenicity of Histoplasma capsulatum. Infect Immun 55:1355–1358
Merson-Davies LA, Hopwood V, Robert R, Marot-Leblond A, Senet J-M, Odds FC (1991) Reaction of Candida albicans cells of different morphology index with monoclonal antibodies specific for the hyphal form. J Med Microbiol 35:321–324
Meunier-Carpentier F, Armstrong D (1981) Candida anigenemia, as detected by passive hemagglutination inhibition, in patients with disseminated candidiasis or Candida colonization. J Clin Microbiol 13:10–14
Minagi S, Miyake Y, Inagaki K, Tsuru H, Suginaka H (1985) Hydrophobic interaction in Candida albicans and Candida tropicalis adherence to various denture base resin materials. Infect Immun 47:11–14
Minnick AA, Eizember LE, McKee JA, Dolence EK, Miller MJ (1991) Bioassay for siderophore utilization by Candida albicans. Anal Biochem 194:223–229
Mitchell TG, Friedman L (1972) In vitro phagocytosis and intracellular fate of variously encapsulated strains of Cryptococcus neoformans. Infect Immun 5:491–498
Miyakawa Y, Kuribayashi T, Kagaya K, Suzuki M (1992) Role of specific determinants in mannan of Candida albicans serotype A in adherence to human buccal epithelial cells. Infect Immun 60:2493–2499
Molinari A, Gomez MJ, Crateri P, Torosantucci A, Cassone A, Arancia G (1993) Differential cell surface expression of mannoprotein epitopes in yeast and mycelial forms of Candida albicans. Eur J Cell Biol 60:146–153
Moors MA, Stull TL, Blank KJ, Buckley HR, Mosser DM (1992) A role for complement receptor-like molecules in iron acquisition by Candida albicans. J Exp Med 175:1643–1651
Morrow B, Srikantha T, Soll DR (1992) Transcription of the gene for a pepsinogen, PEP1, is regulated by white-opaque switching in Candida albicans. Mol Cell Biol 12:2997–3005
Mukherjee J, Pirofski L-A, Scharff MD, Casadevall A (1993) Antibody-mediated protection in mice with lethal intracerebral Cryptococcus neoformans infection. Proc Natl Acad Sci USA 90:3636–3640
Mukherjee S, Lee S, Mukherjee J, Scharff MD, Casadevall A (1994) Monoclonal antibodies to Cryptococcus neoformans capsular polysaccharide modify the course of intravenous infection in mice. Infect Immun 62: 1079–1088
Murphy JW, Friedman H, Bendinelli M (1993) Infectious agents and pathogenesis: fungal infections and immune responses. Plenum Press, New York
Negroni P (1935) Variacion hacia el tipo R de Mycotorula albicans. Rev Soc Argent Biol 11:449–453
Neilands JB (1981a) Iron absorption and transport in microorganisms. Annu Rev Nutr 1:27–46
Neilands JB (1981b) Microbial iron compounds. Annu Rev Biochem 50:715–731
Newman SL, Bucher C, Rhodes J, Bullock WE (1990) Phagocytosis of Histoplasma capsulatum yeasts and microconidia by human cultured macrophages and alveolar macrophages: cellular cytoskeleton requirement for attachment and ingestion. J Clin Invest 85:223–230
Newman SL, Gootee L, Gabay JE (1993) Human neutrophil-mediated fungistasis against Histoplasma capsulatum. Localization of fungistatic activity to the azurophil granules. J Clin Invest 92:624–631
Newman SL, Chaturvedi S, Klein BS (1994) The WI-1 antigen of Blastomyces dermatitidis yeasts mediates binding to human macrophage CDllb/CD18 (CR3) and CD14. J Immunol 154:753–761
Nikawa H, Iwanaga H, Kameda M, Hamada T (1992) In vitro evaluation of Candida albicans adherence to soft denture-lining materials. J Prosthet Dent 68:804–808
Odds FC (1988) Candida and candidosis. Bailliere Tindall, London
Olaiya AF, Sogin SJ (1979) Ploidy determination of Candida albicans. J Bacteriol 140:1043–1049
Oldstone MBA (1987) Molecular mimicry and autoimmune diseases. Cell 50:819–820
Ollert MW, Wadsworth E, Calderone RA (1990) Reduced expression of the functionally active complement receptor for iC3b but not for C3d on an avirulent mutant of Candida albicans. Infect Immun 58:909–913
Pine L, Boone CJ (1968) Cell wall composition and serological reactivity of Histoplasma capsulatum serotypes and related species. J Bacteriol 96:789–798
Ponton J, Jones JM (1986) Analysis of cell wall extracts of Candida albicans by sodium dodecyl sulfate-polyacrylamide gel electrophoresis and Western blot techniques. Infect Immun 53:565–572
Poor AH, Cutler JE (1979) Partially purified antibodies used in a solid-phase radioimmunoassay for detecting candidal antigenemia. J Clin Microbiol 9:362–368
Poulain D, Tronchin G, Vernes A, Popeye R, Biguet J (1983) Antigenic variations of Candida albicans in vivo and in vitro — relationships between P antigens and serotypes. Sabouraudia 21:99–112
Poulain D, Hopwood V, Vernes A (1985) Antigenic variability of Candida albicans. CRC Crit Rev Microbiol 12:223–270
Poulain D, Mackenzie DWR, Van Cutsem J (1991) Monoclonal antibody-gold silver staining dot assay for the detection of antigenaemia in candidosis. Mycoses 34:221–226
Price MF, Gentry LO (1986) Incidence and significance of Candida antigen in low-risk and high-risk patient populations. Eur J Clin Microbiol 5:416–419
Ray TL, Payne CD (1990) Candida albicans acid proteinase: a role in virulence. In: Ayoub EM, Cassell GH, Branche WC, et al (eds) Microbial determinants of virulence and host response. American Society for Microbiology, Washington, pp 163–178
Ray TL, Payne CD (1991) Candida albicans acid proteinase: characterization and role in candidiasis. In: Dunn BM (ed) Structure and function of the aspartic proteinases: genetics, structure, mechanisms. Plenum Press, New York
Regulez P, Arilla MC, Bikandi J, Quindos G, Cisterna R, Ponton J (1992) Identification of antigens reacting with anti-Candida albicans germ tube antibodies. Eur J Epidemiol 8:356–361
Reiss E (1986) Molecular immunology of mycotic and actinomycotic infections. Elsevier, New York
Reiss E, Kuykendall RJ, Kaufman L (1986) Antigenemia in rabbits with Candida albicans serotype B: detection by enzyme immunoassay and preliminary characterization of the antigen. J Med Vet Mycol 24:259–269
Restrepo A, Greer DL (1983) Paracoccidioidomycosis. In: Di Salvo AF (ed) The occupational mycoses. Lea & Febiger, Philadelphia, pp 43–64
Restrepo A, deBedout C, Cano LE, Arango MD, Bedoya V (1981a) Recovery of Paracoccidioides brasiliensis from a partially calcified lymph node lesion by micro-aerophilic incubation of liquid media. Sabouraudia 19:295–300
Restrepo A, Jimenez BE, deBedout C (1981b) Paracoccidioides brasiliensis under microaerophilic conditions. Sabouraudia 19:301–305
Restrepo A, Salazar ME, Cano LE, Stover EP, Feldman D, Stevens DA (1984) Estrogens inhibit mycelium-to-yeast transformation in the fungus Paracoccidioides brasiliensis: implications for resistance of females to paracoccidioidomycosis. Infect Immun 46:346–353
Restrepo-Moreno A (1993) Paracoccidioidomycosis. In: Murphy JW, Friedman H, Bendinelli M (eds) Infectious agents and pathogenesis: fungal infections and immune responses. Plenum Press, New York, pp 251–276
Rhodes JC (1988) Virulence factors in fungal pathogens. Microbiol Sci 5:252–254
Richards S, Russell C (1987) The effect of sucrose on the colonization of acrylic by Candida albicans in pure and mixed culture in an artificial mouth. J Appl Bacteriol 62:421–427
Riesselman MH, Kanbe T, Cutler JE (1991) Improvements and important considerations of an ex vivo assay to study interactions of Candida albicans with splenic tissue. J Immunol Methods 1450:153–160
Riggsby WS, Torres-Bauza LJ, Wills JW, Townes TM (1982) DNA content, kinetic complexity, and the ploidy question in Candida albicans. Mol Cell Biol 2:853–862
Rippon JW (1988) Medical mycology: the pathogenic fungi and the pathogenic actinomycetes. WB Saunders, Philadelphia
Roberts SOB (1969) Pityrosporum orbiculare: incidence and distribution on clinically normal skin. Br J Dermatol 81:264–269
Roth FJ, Goldstein MI (1961) Inhibition of growth of pathogenic yeasts by human serum. J Invest Dermatol 36:383–387
Roth FJ, Boyd CC, Sagami S, Blank H (1959) An evaluation of the fungistatic activity of serum. J Invest Dermatol 32:549–556
Rotrosen D, Calderone RA, Edwards JE (1986) Adherence of Candida species to host tissues and plastic. Rev Infect Dis 8:73–85
Rustchenko-Bulgac EP (1991) Variations of Candida albicans electrophoretic karyotypes. J Bacteriol 173: 6586–6596
Rustchenko-Bulgac EP, Sherman F, Hicks JB (1990) Chromosomal rearrangements associated with morphological mutants provide a means for genetic variation of Candida albicans. J Bacteriol 172:1276–1283
Salazar ME, Restrepo A, Stevens DA (1988) Inhibition by estrogens of conidium-to-yeast conversion in the fungus Paracoccidioides brasiliensis. Infect Immun 56:711–713
San-Blas F (1986) Ultrastructure of spore formation in Paracoccidioides brasiliensis. J Med Vet Mycol 24:203–210
San-Blas G (1985) Paracoccidioides brasiliensis: cell wall glucans, pathogenicity, and dimorphism. In: McGinnis MR (ed) Current topics medical mycology. Springer, Berlin Heidelbery New York, pp 235–357
San-Blas G, Vernet D (1977) Induction of the synthesis of cell wall α-1,3-glucan in the yeastlike form of Paracoccidioides brasiliensis strain IVIC Pb9 by fetal calf serum. Infect Immun 15:897–902
San-Blas G, San-Blas F, Ormaechea E, Serrano LE (1977a) Cell wall analysis of an adenine-requiring mutant of the yeast-like form of Paracoccidioides brasiliensis strain IVIC Pb9. Sabouraudia 15:297–303
San-Blas G, San-Blas F, Serrano LE (1977b) Host-parasite relationships in the yeastlike form of Paracoccidioides brasiliensis strain IVIV Pb9. Infect Immun 15:343–346
Sanchez S, Carbonell LM (1975) Immunological studies on Histoplasma capsulatum. Infect Immun 11:387–394
Sandin RL, Rogers AL, Patterson RJ, Beneke ES (1982) Evidence for mannose-mediated adherence of Candida albicans to human buccal cells in vitro. Infect Immun 35:79–85
Sanford JE, Lupan DM, Schlageter AM, Kozel TR (1990) Passive immunization against Cryptococcus neoformans with an isotype-switch family of monoclonal antibodies reactive with cryptococcal polysaccharide. Infect Immun 58:1919–1923
Sano A, Miyaji M, Nishimura K, de Franco MF (1991) Studies on the relationship between the pathogenicity of Paracoccidioides brasiliensis in mice and its growth rate under different oxygen atmospheres. Mycopathologia 114:93–101
Saxena A, Calderone RA (1990) Purification and characterization of the extracellular C3d-binding protein of Candida albicans. Infect Immun 58:309–314
Schaffner A, Davis CE, Schaffner T, Markert M, Douglas H, Braude AI (1986) In vitro susceptibility of fungi to killing by neutrophil granulocytes discriminates between primary pathogenicity and opportunism. J Clin Invest 78:511–524
Scheid WM, Brown RS, Harding SA, Sande MA (1988) Detection of circulating antigen in experimental Candida albicans endocarditis by an enzyme-linked immunosorbent assay. J Clin Microbiol 12:679–683
Scherer S, Magee PT (1990) Genetics of Candida albicans. Microbiol Rev 54:226–241
Schwyn B, Neilands JB (1987) Universal chemical assay for the detection and determination of siderophores. Anal Biochem 160:47–56
Segal E, Gottfried L, Lehrer N (1988) Candidal vaginitis in hormone-treated mice: prevention by a chitin extract. Mycopathologia 102:157–163
Segal E, Kremer I, Daylan D (1992) Inhibition of adherence of Candida albicans to acrylic by a chitin derivative. Eur J Epidemiol 8:350–355
Shepherd MG (1985) Pathogenicity of morphological and auxotrophic mutants of Candida albicans in experimental infections. Infect Immun 50:541–544
Shepherd MG (1987) Cell envelope of Candida albicans. CRC Crit Rev Microbiol 15:7–25
Shibata N, Kobayashi H, Tojo M, Suzuki S (1986) Characterization of phosphomannan-protein complexes isolated from viable cells of yeast and mycelial forms of Candida albicans NIH B-792 strain by the action of Zymolyase-100T. Arch Biochem Biophys 251:697–708
Shibata N, Arai M, Haga E, Kikuchi T, Najima M, Satoh T, Kobayashi H, Suzuki S (1992) Structural identification of an epitope of antigenic factor 5 in mannans of Candida albicans NIH B-792 (Serotype B) and J-1012 (Serotype A) as Beta-l,2-linked oligomannosyl residues. Infect Immun 60:4100–4110
Shibata N, Hisamichi K, Kobayashi H, Suzuki S (1993) Complete assignment of *H and 13C nuclear magnetic resonance chemical shifts of β-1,2-linked manno-oligosaccharides isolated from the phosphomannan of the pathogenic yeast Candida albicans NIH B-792 strain. Arch Biochem Biophys 302:113–117
Simonson C, Brener D, DeVoe IW (1982) Expression of a high-affinity mechanism for acquisition of transferrin iron by Neisseria meningitidis. Infect Immun 36:107–113
Sixbey JW, Fields BT, Sun CN, Clark RA, Nolan CM (1979) Interactions between human granulocytes and Blastomyces dermatitidis. Infect Immun 23:41–44
Slutsky B, Buffo J, Soll DR (1985) High frequency switching of colony morphology in Candida albicans. Science 230:666–669
Slutsky B, Staebell M, Anderson J, Risen L, Pfaller M, Soll DR (1987) “White-opaque transition”: a second high-frequency switching system in Candida albicans. J Bacteriol 169:189–197
Smail EH, Cronstein BN, Mushulam T, Esposito AL, Ruggeri RW, Diamond RD (1992) In vitro Candida albicans releases the immune modulator adenosine and a second, high-molecular weight agent that blocks neutrophil killing. J Immunol 148:3588–3595
Soll DR (1988) High-frequency in switching in Candida albicans and its relations to vaginal candidiasis. Am J Obstet Gynecol 158:997–1001
Soll DR, Galask R, Isley S, Rao TVG, Stone D, Hicks J, Schmid J, Mac K, Hanna C (1989) Switching of Candida albians during successive episodes of recurrent vaginitis. J Clin Microbiol 27:681–690
Staddon W, Todd T, Irvin RT (1990) Equilibrium analysis of binding of Candida albicans to human buccal epithelial cells. Can J Biochem 36:336–340
Stevens DA (1989) The interface of mycology and endocrinology. J Med Vet Mcyol 27:133–140
Stover EP, Schar G, Clemons KV, Stevens DA, Feldman D (1986) Estradiol-binding proteins from mycelial and yeast-form cultures of Paracoccidioides brasiliensis. Infect Immun 51:199–203
Stull TL (1987) Protein sources of heme for Haemophilus influenzae. Infect Immun 55:148–153
Sugar AM (1993) Blastomycosis. In: Murphy JW, Friedman H, Bendinelli M (eds) Infectious agents and pathogenesis: fungal infections and immune responses. Plenum Press, New York, pp 151–172
Sundstrom PM, Kenny GE (1984) Characterization of antigens specific to the surface of germ tubes of Candida albicans by immunofluorescence. Infect Immun 43: 850–855
Sundstrom PM, Kenny GS (1985) Enzymatic release of germ tube-specific antigens from cell walls of Candida albicans. Infect Immun 49:609–614
Sundstrom PM, Nichols EJ, Kenny GE (1987) Antigenic differences between mannoproteins of germ tubes and blastospores of Candida albicans. Infect Immun 55: 616–620
Sundstrom PM, Tarn MR, Nichols EJ, Kenny GE (1988) Antigenic differences in the surface mannoproteins of Candida albicans as revealed by monoclonal antibodies, Infect Immun 56:601–606
Sweet SP, Douglas LJ (1991a) Effect of iron concentration on siderophore synthesis and pigment production by Candida albicans. FEMS Microbiol Lett 80:87–92
Sweet SP, Douglas LJ (1991b) Effect of iron deprivation on surface composition and virulence determinants of Candida albicans. J Gen Microbiol 137:859–865
Tokunaga M, Kusamichi M, Koike H (1986) Ultrastructure of outermost layer of cell wall in Candida albicans observed by rapid-freezing technique. J Electron Microsc 35:237–246
Tosh FD, Douglas LJ (1992) Characterization of a fucoside-binding adhesin of Candida albicans. Infect Immun 60:4734–4739
Tronchin G, Bouchara J-P, Robert R, Senet J-M (1988) Adherence of Candida albicans germ tubes to plastic: ultrastructural and molecular studies of fibrillar adhesins. Infect Immun 56:1987–1993
Tronchin G, Bouchara JP, Annaix V, Robert R, Senet JM (1991) Fungal cell adhesion molecules in Candida albicans. Eur J Epidemiol 7:23–33
Turner SH, Cherniak R, Reiss E (1984) Fractionation and characterization of galactoxylomannan from Cryptococcus neoformans. Carbohydr Res 125:343–349
Van der Rijn I, Zabriskie JB, McCaryt M (1977) Group A streptococcal antigens cross-reactive with myocardium: purification of heart-reactive antibody and isolation and characterization of the streptococcal antigen. J Exp Med 146:579–599
van Voorhis WC, Eisen H (1989) A surface antigen of Trypanosoma cruzi that mimics mammalian nervous tissue. J Exp Med 169:641–652
Vartivarian SE (1992) Virulence properties and nonimmune pathogenetic mechanisms of fungi. Clin Infect Dis 14(Suppl 1):S30-S36
Vartivarian SE, Reyes GH, Jacobson ES, James PG, Cherniak R, Mumaw VR, Tigler MJ (1989) Localization of mannoprotein in Cryptococcus neoformans. J Bacteriol 171:6850–6852
Vartivarian SE, Anaissie EJ, Cowart RE, Sprigg HA, Tingler MJ, Jacobson ES (1993) Regulation of cryp-tococcal capsular polysaccharide by iron. J Infect Dis 167:186–190
Vasilas A, Molinda L, Hoffman M, Haidaris CG (1992) The influence of morphological variation on Candida albicans adhesion to denture acrylic in vitro. Arch Oral Biol 37:613–622
Vecchiarelli A, Cenci E, Puliti M, Blasi E, Puccetti P, Cassone A, Bistoni F (1989) Protective immunity inducted by low-virulence Candida albicans: cytokine production in the development of the anti-infectious state. Cell Immunol 124:334–344
Vudhichamnong K, Walker DM, Ryley HC (1982) The effect of secretory immunoglobulin A on the in vitro adherence of the yeast Candida albicans to human oral epithelial cells. Arch Oral Biol 27:617–621
Warr W, Bates JH, Stone A (1968) The spectrum of pulmonary cryptococcosis. Ann Intern Med 69: 1109–1125
Weinberg ED (1971) Roles of iron in host-parasite interactions. J Infect Dis 124:401–410
Weinberg ED (1975) Nutritional immunity: host’s attempt to withhold iron from microbial invaders. JAMA 231: 39–41
Weinberg ED (1978) Iron and infection. Microbiol Rev 42:45–66
Weinberg ED (1984) Iron witholding: a defense against infection and neoplasia. Physiol Rev 64:65–102
Weiner MH, Coats-Stephen M (1979) Immunodiagnosis of systemic candidiasis: mannan antigenemia detected by radioimmunoassay in experimental and human infections. J Infect Dis 140:989–993
Weiner MH, Yount WJ (1976) Mannan antigenemia in the diagnosis of invasive Candida infections. J Clin Invest 58:1045–1053
West BC, Kwon-Chung KJ (1980) Mycetoma caused by Microsporum audouinii. Am J Clin Pathol 73:447–454
Whelan WL, Soll DR (1982) Mitotic recombination in Candida albicans: recessive lethal alleles linked to a gene required for methionine biosynthesis. Mol Gen Genet 187:477–485
Whelan WL, Partridge RM, Magee PT (1980) Heterozygosity and segregation in Candida albicans. Mol Gen Genet 180:107–113
Whelan WL, Delga JM, Wadsworth E, Walsh TJ, Kwon-Chung KJ, Calderone R, Lipke PN (1990) Isolation and characterization of cell surface mutants of Candida albicans. Infect Immun 58:1552–1557
Williamson PR, Bennett JE, Robbins J, Schneerson R (1993) Vaccination for prevention of cryptococcosis. 2nd Int Conf on Cryptococcus and cryptococcosis, Abstr L22
Wu-Hsieh B, Howard DH (1993) Histoplasmosis. In: Murphy JW, Friedman H, Bendinelli M (eds) Infectious agents and pathogenesis: fungal infections and immune responses. Plenum Press, New York, pp 213–250
Yuki N, Taki T, Inagaki F, Kasama T, Takahashi M, Saito K, Handa S, Miyatake T (1993) A bacterium lipopolysaccharide that elicits Guillain-Barre syndrome has a GM1 ganglioside-like structure. J Exp Med 178:1771–1775
Zebedee S, Koduri RK, Mukheijee J, Mukheijee S, Lee S, Sauer DF, Scharff MD, Casadevall A (1994) Mouse-human immunoglobulin GI chimeric antibodies with activities against Cryptococcus neoformans. Antimicrob Agents Chemother 38:1507–1514
Zimmermann L, Hantke K, Braun V (1984) Exogenous induction of the iron dicitrate transport system of Escherichia coli K-12. J Bacteriol 159:271–277
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Cutler, J.E., Han, Y. (1996). Fungal Factors Implicated in Pathogenesis. In: Howard, D.H., Miller, J.D. (eds) Human and Animal Relationships. The Mycota, vol 6. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-662-10373-9_1
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