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Mitochondrial Genetics of Yeast

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Book cover Genetics and Biotechnology

Part of the book series: The Mycota ((MYCOTA,volume 2))

Abstract

Biosynthesis of functional mitochondria is a complex affair, where hundreds of proteins are required to build up the organelle and to keep it functional. The main contribution to mitochondrial (mt) structure and function is provided by the nuclear DNA, whereas the contribution of the mt genome is comparatively modest, but nonetheless essential. Mutations in both compartments can lead to mt dysfunction, and in most eukaryotic organisms this represents a lethal event. The great advantage of yeast is the ability to provide the energy by respiration and by fermentation, so that genetic approaches are feasible to unravel mt biogenesis, mt functions and the regulatory mechanisms responsible for balancing both genetic systems.

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  1. Institut für Biologie IV (Mikrobiologie), Rheinisch-Westfälischen Technischen Hochschule Aachen, Worringer Weg, D-52056, Aachen, Germany

    K. Wolf

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  1. Allgemeine Botanik, Ruhr-Universität, D-44780, Bochum, Germany

    Ulrich Kück

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Wolf, K. (1995). Mitochondrial Genetics of Yeast. In: Kück, U. (eds) Genetics and Biotechnology. The Mycota, vol 2. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-662-10364-7_6

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