Stress Responses in S. pombe
Cells, especially single cell organisms like yeast, must contend with frequent fluctuations in the availability of nutrients, variations in pH, temperature and external osmolarity, exposure to UV irradiation, dehydration and a large range of potentially toxic environmental compounds. In response to abrupt and adverse changes in the quality of their environment unicellular organisms invoke a variety of programmed stress responses. Characterization of these responses — the mechanisms involved in sensing stress, the signaling pathways that transmit that information to various parts of the cell and the resulting compensatory changes in gene expression and metabolism — permits us to understand how cells adapt and survive under non-ideal growth conditions.
KeywordsHeat Stress Osmotic Stress Unfold Protein Response Fission Yeast Heat Shock Factor
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