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Merkel Cells in Human Transplanted Flaps

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The Merkel Cell

Summary

New procedures in the field of reconstructive surgery place more emphasis on the reconstruction of form and function. An important aspect is the touch perception of the transplanted tissue surface. The results of this study, involving the free radial forearm flap and the latissimus dorsi flap, allow the assumption that a nerve reconstruction is not necessary, because good reinnervation in most parts of the flaps can be observed. Merkel cells can be found within the hairy skin of most body regions. For the detection of Merkel cells CK 20 antibodies were used. Seven days after operation as well as after 2 and 4 months postoperative, CK 20-positive cells were found in the transplant. These results correlated with good recovery of touch perception.

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References

  • Baumann I, Greschnik A, Bootz F, Kaiserling E (1996) Freie transplantierte, mikrovaskulär reanastomosierte Unterarmlappen zur Rekonstruktion in Mundhöhle und Oropharynx. HNO 44: 616–623

    Article  PubMed  CAS  Google Scholar 

  • Boyd B, Mulholland S, Gullane P, Rotstein L, Brown D (1994) Reinnervated lateral antebrachial neurosome flaps: are we making sense? Plast Reconst Surg 93: 1350–1359

    Article  PubMed  CAS  Google Scholar 

  • Costas PD, Heatley G, Seckel BR (1994) Normal sensation of the human face and neck.

    Google Scholar 

  • Plast Reconst Surg 93:1141–1145

    Google Scholar 

  • English KB (1977) The ultrastructure of cutaneous type I mechanoreceptors (Haarscheiben) in cats following denervation. J Comp Neurol 172: 137–164

    Article  PubMed  CAS  Google Scholar 

  • English KB, van Norman DK, Horch K (1983) Effects of chronic denervation in type I cutaneous mechanoreceptors ( Haarscheiben ). Anat Rec 207: 79–88

    Google Scholar 

  • English KB, Horch K, van Norman DK, Burgess PR (1984) Neurothropic influences on cutaneous type I mechanoreceptors. In: Hamann W, Iggo A (eds) Sensory receptor mechanisms. World Scientific, Singapore, pp 36–45

    Google Scholar 

  • English KB, Wang ZZ, Stayner N, Stensaas LJ, Martin H, Tuckett RP (1992) Serotoninlike immunoreactivity in Merkel cells and their afferent neurons in touch domes from the hairy skin of rats. Anat Rec 232: 112–120

    Article  PubMed  CAS  Google Scholar 

  • He L, Tuckett RP, English KB (1999) Chemosensitivity of the rat type I slowly adapting mechanoreceptor. Biol Signals Receptors 8: 382–389

    Article  CAS  Google Scholar 

  • Horch K (1984) Specificity in regenerating cutaneous nerves. In: Hamann W, Iggo A (eds) Sensory receptor mechanisms. World Scientific, Singapore, pp 47–55

    Google Scholar 

  • Katou F, Shirai N, Kamekura S, Ohki H, Motegi K, Andoh N, Date F, Nagura H (1995) Intraoral reconstruction with innervated forearm flap. Oral Surg Oral Med Oral Pathol Oral Radiol 80: 638–644

    Article  CAS  Google Scholar 

  • Levin S, Pearsell G, Rudermann W (1978) Von Freys method of measuring pressure sensibility in the hand: an engineering analysis of the Weinstein-Semmes pressure aesthesiometer. J Hand Surg 3: 211–216

    CAS  Google Scholar 

  • Posnick JC, Grossmann JA (2000) Facial sensibility testing: a clinical update. Plast Reconst Surg 106: 892–894

    Article  PubMed  CAS  Google Scholar 

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© 2003 Springer-Verlag Berlin Heidelberg

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Vesper, M., Houdek, P., Moll, I. (2003). Merkel Cells in Human Transplanted Flaps. In: Baumann, K.I., Halata, Z., Moll, I. (eds) The Merkel Cell. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-662-10358-6_5

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  • DOI: https://doi.org/10.1007/978-3-662-10358-6_5

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-05574-4

  • Online ISBN: 978-3-662-10358-6

  • eBook Packages: Springer Book Archive

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