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Patch Testing in Adverse Drug Reactions

  • Chapter
Textbook of Contact Dermatitis

Abstract

A drug eruption is any adverse skin reaction caused by a drug used in normal doses. Systemic exposure to drugs can lead to a wide variety of cutaneous reactions, ranging from erythema to toxic epidermal necrolysis and anaphylaxis. The incidence of these eruptions is not exactly known; 2%–5% of inpatients experience such a reaction, so a dermatologist should see them regularly [1]. Topically applied drugs may cause contact dermatitis reactions. Topical sensitization and subsequent systemic exposure may lead to similar dermatological patterns. It is clear that patch testing can be of great help as a diagnostic tool if contact sensitization has preceded it, as these cases can be regarded as a form of systemic contact dermatitis (Chap. 16) [2].

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Authors
  1. Derk P. Bruynzeel
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Editors and Affiliations

  1. St. John’s Institute of Dermatology, St. Thomas’s Hospital, SE1 7EH, London, UK

    Richard J. G. Rycroft

  2. Department of Dermatology, Gentofte Hospital, University of Copenhagen, Niels Andersens Vej 65, 2900, Hellerup, Denmark

    Torkil Menné

  3. Hautklinik der Städtischen Kliniken Dortmund, Abteilung Dermatologie, Universität Witten/Herdecke, Beurhausstraße 40, 44137, Dortmund, Germany

    Peter J. Frosch

  4. Clinique Dermatologique Laboratoire de Dermatochimie, Univ. Louis Pasteur, 1 Place de L’Hôpital, 67091, Strasbourg, France

    Jean-Pierre Lepoittevin

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© 2001 Springer-Verlag Berlin Heidelberg

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Bruynzeel, D.P. (2001). Patch Testing in Adverse Drug Reactions. In: Rycroft, R.J.G., Menné, T., Frosch, P.J., Lepoittevin, JP. (eds) Textbook of Contact Dermatitis. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-662-10302-9_23

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  • DOI: https://doi.org/10.1007/978-3-662-10302-9_23

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-662-10304-3

  • Online ISBN: 978-3-662-10302-9

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