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Other Potential Dermatological Indications for Tacrolimus

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Tacrolimus Ointment

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Abstract

During the last few decades, the treatment of inflammatory skin disorders consisted mainly of systemic and topical glucocorticosteroids, but their use is limited due to potential side effects. Immunomodulatory macrolides such as cyclosporin and tacrolimus have recently shown therapeutic efficacy in such disorders. However, side effects such as hypertension and nephrotoxicity may occur after oral administration. Thus, a topical formulation was needed for the treatment of inflammatory skin disorders.

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  1. T. Assmann
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  2. T. Ruzicka
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Editors and Affiliations

  1. Universitätsklinikum Düsseldorf Hautklinik, Heinrich-Heine-Universität, Moorenstraße 5, 40225, Düsseldorf, Germany

    Thomas Ruzicka

  2. Hospital for Skin and Allergic Diseases, Department of Dermatology, Helsinki University Central Hospital, Meilahdentie 2, 00250, Helsinki, Finland

    Sakari Reitamo

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Assmann, T., Ruzicka, T. (2004). Other Potential Dermatological Indications for Tacrolimus. In: Ruzicka, T., Reitamo, S. (eds) Tacrolimus Ointment. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-662-10209-1_11

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  • DOI: https://doi.org/10.1007/978-3-662-10209-1_11

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