Radiation Injury

  • H. A. Vuilleumier
  • E. D. Reis


Deleterious effects of radiation on normal tissues were recognized soon after Roentgen’s original publication on “A New Kind of Ray” in 1885 [65]. Rowland [66] reported a case of actinic dermatitis in 1896 and Walsh [78] reported gastrointestinal toxicity in 1887. Thereafter, radiation-related damage to all organs has been described and extensively studied. Despite the evolution of radiotherapy into a more powerful, accurate, and safer tool for tumor control, radiation injury remains its most important limiting factor. In fact, as this modality gained broader applications, a parallel increase in the number of patients with radiation-induced complications has been seen [1,50].


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© Springer-Verlag Berlin Heidelberg 1998

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  • H. A. Vuilleumier
  • E. D. Reis

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