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Polyposis Syndromes

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Surgical Management of Anorectal and Colonic Diseases

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Abstract

First described as a mendelian dominant trait by Cuthbert Dukes in 1930 [20], the syndromes of multiple polyps of the gastrointestinal (GI) tract, particularly the colon and rectum, have later been found to be much more complex. It is now recognized that a number of different syndromes exists in which pedunculated or sessile polyps may arise and involve the mucosa of various parts of the digestive tract. These growths may be single or multiple and may or may not show a familial pattern. Histological features may be those of an inflammatory mass, hamartoma, lymphoid polyp, lipoma, lymphosarcoma, neurofibroma, or the mucosal cell growth known as adenoma. The literature is replete with different denominations for these conditions, and it is clear that syndromes overlap. The original, concise definitions are now interacting within a larger picture of mucosal cell transformation.

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Authors
  1. J.-C. Givel
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  2. E. D. Reis
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Editors and Affiliations

  1. Départment de Chirurgie, Policlinique de Chirurgie, Hôpital Cantonal, Rue Micheli-du-Crest 24, CH-1211, Genève 4, Switzerland

    Marc-Claude Marti

  2. Service de Chirurgie A, Centre Hospitalier Universitaire Vaudois, CH-1011, Lausanne, Switzerland

    Jean-Claude Givel

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© 1998 Springer-Verlag Berlin Heidelberg

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Givel, JC., Reis, E.D. (1998). Polyposis Syndromes. In: Marti, MC., Givel, JC. (eds) Surgical Management of Anorectal and Colonic Diseases. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-662-10169-8_31

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  • DOI: https://doi.org/10.1007/978-3-662-10169-8_31

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-662-10171-1

  • Online ISBN: 978-3-662-10169-8

  • eBook Packages: Springer Book Archive

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