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Symptoms and Signs of Myocardial Ischemia

  • Eugenio Picano

Abstract

A transient regional imbalance between oxygen demand and supply usually results in myocardial ischemia, the signs and symptoms of which can be used as a diagnostic tool. Myocardial ischemia results in a typical “cascade” of events in which the various markers are hierarchically ranked in a well-defined time sequence [2]. The flow heterogeneity, especially between the subendocardial and subepicardial perfusion, is the forerunner of ischemia, followed by the metabolic changes, by the alterations in the ventricular diastolic relaxation, by the regional dyssynergy, and only at a later stage by electrocardiographic changes, global left ventricular dysfunction, and pain (Fig. 1).

Keywords

Myocardial Ischemia Coronary Flow Reserve Wall Motion Abnormality Normal Coronary Artery Flow Heterogeneity 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Springer-Verlag Berlin Heidelberg 1997

Authors and Affiliations

  • Eugenio Picano
    • 1
  1. 1.Institute of Clinical PhysiologyCNRPisaItaly

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