Stress Echocardiography Applications Beyond Coronary Artery Disease: Dilated Cardiomyopathy

  • Massimo Pozzoli


In patients with dilated cardiomyopathy, the indications for stress echocardiography are uncertain and its application has not yet become routine, despite the sound rationale supporting the assessment of contractile reserve in a disease primarily characterized by systolic dysfunction. In addition, the use of a noninvasive, nonionizing means for serial assessment is particularly attractive in this chronic condition, which may require repeated evaluations during follow-up.


Dilate Cardiomyopathy Stress Echocardiography Ischemic Cardiomyopathy Dobutamine Stress Intermittent Infusion 
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  1. 1.
    Tan LB (1986) Cardiac pumping capability and prognosis in heart failure. Lancet 2: 1360–1363PubMedCrossRefGoogle Scholar
  2. 2.
    Dubois-Randé JL, Merlet P, Roudot F et al. (1992) Beta-adrenergic contractile reserve as a predictor of clinical outcome in patients with idiopatic dilated cardiomyopathy. Am Heart J 124: 679–685PubMedCrossRefGoogle Scholar
  3. 3.
    Fowler MB, Laser JA, Hopkins GL et al. (1986) Assessment of the beta-adrenergic receptor pathway in the intact failing human heart: progressive receptor down-regulation and sub-sensitivity to agonist response. Circulation 74: 1290–1302PubMedCrossRefGoogle Scholar
  4. 4.
    Colucci WS, Leatherman GF, Ludmer PL et al. (1987) Beta-adrenergic inotropic responsiveness of patients with heart failure: studies with intracoronary dobutamine infusion. Circulation Research 61 [Suppl 19]: 182–186Google Scholar
  5. 5.
    Marcus RH, Lang RM, Neuman NA et al. (1991) A physiological approach to drug therapy in dilated cardiomyopathy. Echocardiography 8: 173–186PubMedCrossRefGoogle Scholar
  6. 6.
    Mannor A, Schneeweiss A (1997) Prognostic value of noninvasively obtained left ventricular contractile reserve in patients with severe heart failure. J Am Coll Cardiol 29: 422–428CrossRefGoogle Scholar
  7. 7.
    Pozzoli M, Capomolla S, Cioffi G et al. (1996) Prognostic significance of low-dose dobutamine test in patients with advanced congestive heart failure due to dilated cardiomyopathy. J Am Coll Cardiol 27 [Suppl Al: 329AGoogle Scholar
  8. 8.
    Kitaoka H, Takata J, Yabe T, Furuno T, Matsumura Y, Chikamori T, Doi Y (1997) Dobutamine stress echocardiography can predict the improvement of left ventricular systolic function in dilated cardiomyopathy. J Am Coll Cardiol 29 [Suppl A]: 22AGoogle Scholar
  9. 9.
    Klewer SE, Goldberg SJ, Donnerstein RL et al. (1992) Dobutamine stress echocardiography: a sensitive indicator of diminished myocardial function in asymptomatic doxorubicintreated long-term survivors of childhood cancer. J Am Coll Cardiol 19: 394–401PubMedCrossRefGoogle Scholar
  10. 1o.
    Mariotti E, Agostini A, Angelucci E, Lucarelli G, Sgarbi E, Picano E (1996) Reduced left ventricular contractile reserve identified by low dose dobutamine echocardiography as an early marker of cardiac involvement in asymptomatic patients with thalassemia major. Echocardiography 13: 463–472PubMedCrossRefGoogle Scholar
  11. 11.
    Perez JE, Waggoner AD, Davila-Roman VG et al. (1992) On-line quantification of ventricular function during dobutamine stress echocardiography. Eur Heart J 13: 1669–1676PubMedGoogle Scholar
  12. 12.
    Sharp SM, Sawada SG, Segar DS et al. (1994) Dobutamine stress echocardiography: detection of coronary artery disease in patients with dilated cardiomyopathy. J Am Coll Cardiol 24: 934–939Google Scholar
  13. 13.
    Vigna C, Russo A, De Rito V et al. (1996) Regional wall motion analysis by dobutamine stress echocardiography to distinguish between ischemic and non-ischemic dilated cardiomyopathy. Am Heart J 131: 537–543PubMedCrossRefGoogle Scholar
  14. 14.
    Iskandrian AS, Helfeld H, Lemlek J et al. (1992) Differentiation between primary dilated cardiomyopathy and ischemic cardiomyopathy based on right ventricular performance. Am Heart J 123: 768–773PubMedCrossRefGoogle Scholar
  15. 15.
    Tauberg SG, Orie JE, Bartlett BE et al. (1993) Usefulness of thallium 201 for distinction from idiopathic dilated cardiomyopathy. Am J Cardiol 71 674–680PubMedCrossRefGoogle Scholar
  16. 16.
    Bach DS, Muller DWM, Gros BJ, Armstrong F (1994) False positive dobutamine stress echocardiograms: characterization of clinical, echocardiographic and angiographic findings. J Am Coll Cardio 1128: 804–813Google Scholar
  17. 17.
    Cioffi G, Pozzoli M, Franchini M, Forni G, Traversi E, Cobelli F, Tavazzi L (1997) Noninvasive assessment of contractile reserve by dobutamine Doppler echocardiography in patients with chronic congestive heart failure: comparison with invasive hemodynamic measurements. J Am Coll Cardiol 29 (2) [Suppl A]: 116AGoogle Scholar

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© Springer-Verlag Berlin Heidelberg 1997

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  • Massimo Pozzoli

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