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Kreislaufveränderungen beim septischen Syndrom

  • Chapter
Sepsis

Zusammenfassung

Mit einer Mortalitätsrate von 50–80% ist die Sepsis eine häufige Todesursache schwerstkranker Patienten. Derzeit wird nicht mehr so eindeutig wie früher eine Störung der zentralen Kreislaufregulation bzw. ein Schockzustand infolge Sepsis für den Tod verantwortlich gemacht. Vielmehr scheint der Tod septischer Patienten hauptsächlich mit der Entwicklung eines multiplen Organversagens („multiple systems organ failure“, MSOF) [7, 24] einherzugehen. Um das MSOF und die zirkulatorischen Konsequenzen einer schweren Infektion zu verstehen, konzentrierte sich die Forschung auf Störungen der Mikrozirkulation, die mit einer Sepsis einhergehen.

Diese Arbeit wurde unterstützt durch Zuwendungen des Medical Research Council of Canada (Nr. MA7339), der Ontario Heart Foundation und der UpJohn Company (Nr. 8244) von Kanada.

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Authors
  1. W. J. Sibbald
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  2. R. F. Raper
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  3. A. D. Bersten
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Editors and Affiliations

  1. Universitätsklinikum Steglitz Klinik für Anästhesiologie und operative Intensivmedizin, Freie Universität Berlin, Hindenburgdamm 30, D-1000, Berlin 45, Deutschland

    K. Reinhart  & K. Eyrich  & 

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© 1989 Springer-Verlag Berlin Heidelberg

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Sibbald, W.J., Raper, R.F., Bersten, A.D. (1989). Kreislaufveränderungen beim septischen Syndrom. In: Reinhart, K., Eyrich, K. (eds) Sepsis. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-662-09869-1_11

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  • DOI: https://doi.org/10.1007/978-3-662-09869-1_11

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-662-09870-7

  • Online ISBN: 978-3-662-09869-1

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