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Defective and Defective Interfering RNAs of Monopartite Plus-strand RNA Plant Viruses

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Satellites and Defective Viral RNAs

Part of the book series: Current Topics in Microbiology and Immunology ((CT MICROBIOLOGY,volume 239))

Abstract

The defective interfering (DI) RNAs represent one of several classes of symptom-modulating RNAs identified in association with RNA plant virus infections. Structurally, these molecules are derived from, and represent mutant forms of, the viral genome (Perrault 1981; Lazzarini et al. 1981). DI RNAs may contain distinct types of modifications; however, the most prevalent is the deletion of one or more large segments of sequence. Despite structural differences, the common effect of the mutation(s) is to render the DI RNAs dependent on their nondefective ‘parental’ genome for essential viral replication proteins. This, in turn, limits replication of these molecules to cells which are coinfected with the parental genome.

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Authors and Affiliations

  1. Department of Biology, York University, 4700 Keele Street, Toronto, Ontario, M3J 1P3, Canada

    K. A. White

  2. School of Biological Sciences, University of Nebraska, Lincoln, NE, 68588-0118, USA

    T. J. Morris

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  1. K. A. White
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  2. T. J. Morris
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Editors and Affiliations

  1. Division of Oncovirology, Mail Drop & Room BCC239, Department of Molecular and Experimental Medicine, The Scripps Research Institute, 10550 N. Torrey Pines Road, La Jolla, CA, 92037, USA

    Peter K. Vogt Ph.D.

  2. Department of Plant and Microbial Biology, University of California, Berkeley, Berkeley, CA, 94720, USA

    Andrew O. Jackson Ph.D.

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© 1999 Springer-Verlag Berlin Heidelberg

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White, K.A., Morris, T.J. (1999). Defective and Defective Interfering RNAs of Monopartite Plus-strand RNA Plant Viruses. In: Vogt, P.K., Jackson, A.O. (eds) Satellites and Defective Viral RNAs. Current Topics in Microbiology and Immunology, vol 239. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-662-09796-0_1

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  • DOI: https://doi.org/10.1007/978-3-662-09796-0_1

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