Uridine and Pyrimidine Nucleotides in Cell Function

  • G. P. Connolly
Part of the Purinergic and Pyrimidinergic Signalling book series (HEP, volume 151 / 1)


The pyrimidine nucleosides, e.g. uridine and cytidine and the related nucleotides UDP and UTP, are endogenous cellular constituents that can modulate cell function at both the intra- and extra-cellular levels. Many disorders of pyrimidine metabolism are linked to altered cytidine and uracil metabolism, leading to systemic and neurological dysfunction. Pyrimidines can also alter cell activity, under physiological and pathological circumstances, via the activation of cell surface P2Y receptors (Communi and Boeynams 1997; Boarder and Webb, Chap. 4, this volume).


Orotic Acid Pyrimidine Nucleoside Pyrimidine Nucleotide Pyrimidine Metabolism Uridine Phosphorylase 
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