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Nucleoside and Nucleotide Transmission in Sensory Systems

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Book cover Purinergic and Pyrimidinergic Signalling I

Part of the book series: Purinergic and Pyrimidinergic Signalling ((HEP,volume 151 / 1))

Abstract

Nucleotide and nucleoside signaling occurs via autocrine, paracrine, and neurotransmission modes, mediated by P2 (nucleotide) and P1 (adenosine A1–A3) receptor transduction paths, dynamically linked to purine and pyrimidine release (ATP, associated hydrolysis products, adenosine, diadenosine polyphosphates (ApnA), and pyrimidines (particularly UTP), and extra-cellular hydrolysis, phosphorylation and reuptake pathways.

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  1. G. D. Housley
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  1. Institute of Pharmacological Sciences, University of Milan, Via Balzaretti, 9, 20133, Milan, Italy

    Maria Pia Abbracchio

  2. Department of Molecular Pharmacology and Biological Chemistry, Northwestern University Medical School, Searle 8-477 (S-215), 303 East Chicago Avenue, 60611, Chicago, IL, USA

    Michael Williams

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Housley, G.D. (2001). Nucleoside and Nucleotide Transmission in Sensory Systems. In: Abbracchio, M.P., Williams, M. (eds) Purinergic and Pyrimidinergic Signalling I. Purinergic and Pyrimidinergic Signalling, vol 151 / 1. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-662-09604-8_12

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