The Role of T Cells in Brain Pathology

  • M. Bradl
  • A. Flügel
Part of the Current Topics in Microbiology and Immunology book series (CT MICROBIOLOGY, volume 265)

Abstract

The protective role of T cells in the adaptive immune response is well-established: T cells become activated in the course of infections and migrate to infected organs and tissues including the central nervous system (CNS; Fleischer and Kreth 1983; Müller et al. 1989; Hunter et al. 1992; Quagliarello and Scheld 1992; Kürger et al. 1994). And yet, T cells may also be found in the CNS even when it is seemingly not infected, as seen in human patients with neurodegenerative diseases.

Keywords

Migration Retina Interferon Luminal Neurol 

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Copyright information

© Springer-Verlag Berlin Heidelberg 2002

Authors and Affiliations

  • M. Bradl
    • 1
  • A. Flügel
    • 1
  1. 1.Department of NeuroimmunologyMax-Planck-Institute for NeurobiologyMartinsriedGermany

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