Innate Immune Responses in Viral Encephalitis

  • C. S. Reiss
  • D. A. Chesler
  • J. Hodges
  • D. D. C. Ireland
  • N. Chen
Part of the Current Topics in Microbiology and Immunology book series (CT MICROBIOLOGY, volume 265)


Innate immunity in the central nervous system (CNS) is essential in host responses to pathogens. The brain does not have the continuous monitoring by T cells engaged in immune surveillance nor the lymphatic drainage that are characteristic of the periphery. Similarly, the brain has specialized non-renewing neurons, and thus the effector mechanisms of the peripheral immune system which permit swelling (incompatible with a bony skull) and eliminate infected cells by apoptosis are modified.


Nitric Oxide Natural Killer Cell Innate Immune Response Vesicular Stomatitis Virus Dengue Hemorrhagic Fever 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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Copyright information

© Springer-Verlag Berlin Heidelberg 2002

Authors and Affiliations

  • C. S. Reiss
    • 1
  • D. A. Chesler
    • 1
  • J. Hodges
    • 1
  • D. D. C. Ireland
    • 1
  • N. Chen
    • 1
  1. 1.Biology DepartmentNew York UniversityNew YorkUSA

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