Nuklearmedizinische Verfahren

  • L. Degen
  • C. Beglinger

Zusammenfassung

Obwohl nuklearmedizinische Verfahren vielfach anderen radiologischen Techniken in der anatomischen Bildauflösung unterlegen sind, bieten sie im klinischen Alltag in spezifischen Situationen wichtige Vorteile. Ihren Stellenwert finden sie vor allem in der Analyse von Funktionsabläufen, aber auch in der Diagnostik und Therapie von Tumoren. In der Gastroenterologie bieten sie sich entsprechend in der Abklärung von Motilitätsstörungen und von Blutungen sowie in der Diagnostik entzündlicher und maligner Prozesse an. Neben Grundprinzipien werden wir im nachfolgenden Kapitel neuere nuklearmedizinische Methoden darstellen, deren technische Besonderheiten hervorheben und vor allem klinische Indikationen kritisch beleuchten.

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Literatur

  1. Becker W, Goldenberg DM, Wolf F (1994) The use of monoclonal antibodies and antibody fragments in the imaging of infectious lesions. Semin Nucí Med 24(2):142–153CrossRefGoogle Scholar
  2. Biersack HJ, Grunwald F (1995) Endocrinological applications in nuclear medicine. Semin Nucl Med 25(2):92–110PubMedCrossRefGoogle Scholar
  3. Bunker SR, Brown JM, McAuley RJ, Lull RJ, Jackson JH, Hattner RS, Huberty JP (1982) Detection of gastrointestinal bleeding sites. Use of in vitro technetium Tc 99m-labeled RBCs. JAMA 247(6):789–792PubMedCrossRefGoogle Scholar
  4. Camilleri M, Colemont LJ, Phillips SF, Brown ML, Thomforde GM, Chapman N, Zinsmeister AR (1989) Human gastric emptying and colonic filling of solids characterized by a new method. Am J Physiol 257:G284–G290PubMedGoogle Scholar
  5. Datz FL (1996) Abdominal abscess detection: gallium, 111In-, and 99mTc-labeled leukocytes, and polyclonal and monoclonal antibodies. Semin Nucl Med 26(1):51–64PubMedCrossRefGoogle Scholar
  6. Degen LP, Phillips SF (1996) Variability of gastrointestinal transit in healthy women and men. Gut 39(2):299–305PubMedCrossRefGoogle Scholar
  7. Eary JF (1999) Nuclear medicine in cancer diagnosis. Lancet 354(9181):853–857PubMedCrossRefGoogle Scholar
  8. Fisher RS, Malmud LS, Roberts GS, Lobis IF (1976) Gastroesophageal (GE) scintiscanning to detect and quantitate GE reflux. Gastroenterology 70(3):301–308PubMedGoogle Scholar
  9. Ganz WI, Serafini AN (1989) The diagnostic role of nuclear medicine in the acquired immunodeficiency syndrome. J Nucl Med 30(12):1935–1945PubMedGoogle Scholar
  10. Jacobson AF, Cerqueira MD (1992) Prognostic significance of late imaging results in technetium-99m-labeled red blood cell gastrointestinal bleeding studies with early negative images. J Nucl Med 33(2):202–207PubMedGoogle Scholar
  11. Kilpatrick ZM, Aseron CA Jr (1972) Radioisotope detection of Meckel’s diverticulum causing acute rectal hemorrhage. N Engl J Med 287(13):653–654PubMedCrossRefGoogle Scholar
  12. Klingensmith WC III, Kuni CC, Fritzberg AR (1982) Cholescintigraphy in extrahepatic biliary obstruction. AJR Am J Roentgenol 139(1):65–70PubMedCrossRefGoogle Scholar
  13. Krishnamurthy GT, Turner FE (1990) Pharmacokinetics and clinical application of technetium 99m-labeled hepatobiliary agents. Semin Nucl Med 20(2):130–149PubMedCrossRefGoogle Scholar
  14. Lucas MH, Elgazzar AH (1994) Detection of protein bound vitamin B12 malabsorption. A case report and review of the literature. Clin Nucl Med 19(11):1001–1003PubMedCrossRefGoogle Scholar
  15. Maurer AH, Rodman MS, Vitti RA, Revez G, Krevsky B (1992) Gastrointestinal bleeding: improved localization with cine scintigraphy. Radiology 185(1):187–192PubMedGoogle Scholar
  16. Middleton ML (1996) Scintigraphic evaluation of hepatic mass lesions: emphasis on hemangioma detection. Semin Nucl Med 26(1):4–15PubMedCrossRefGoogle Scholar
  17. Palestro CJ (1994) The current role of gallium imaging in infection. Semin Nucl Med 24(2):128–141PubMedCrossRefGoogle Scholar
  18. Palmer EL, Scott JA, Strauss HW (1992) Practical nuclear medicine. WB Saunders, PhiladelphiaGoogle Scholar
  19. Parkman HP, Miller MA, Fisher RS (1995) Role of nuclear medicine in evaluating patients with suspected gastrointestinal motility disorders. Semin Nucl Med 25(4):289–305PubMedCrossRefGoogle Scholar
  20. Schauwecker DS, Park HM, Mock BH, Burt RW, Kernick CB, Ruoff AC, III, Sinn HJ, Wellman HN (1984) Evaluation of complicating osteomyelitis with Tc-99m MDP, In-111 granulocytes, and Ga-67 citrate. J Nucl Med 25(8):849–853PubMedGoogle Scholar
  21. Sfakianakis GN, Conway JJ (1981) Detection of ectopic gastric mucosa in Meckel’s diverticulum and in other aberrations by scintigraphy: I. Pathophysiology and 10-year clinical experience. J Nucl Med 22(7):647–654PubMedGoogle Scholar
  22. von der Ohe MR, Camilleri M (1992) Measurement of small bowel and colonic transit: indications and methods. Mayo Clin Proc 67:1169–1179PubMedCrossRefGoogle Scholar
  23. Winzelberg GG, McKusick KA, Froelich JW, Callahan RJ, Strauss HW (1982) Detection of gastrointestinal bleeding with 99mTc-labeled red blood cells. Semin Nucl Med 12(2):139–146PubMedCrossRefGoogle Scholar

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© Springer-Verlag Berlin Heidelberg 2002

Authors and Affiliations

  • L. Degen
  • C. Beglinger

There are no affiliations available

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