Skip to main content
SpringerLink
Log in
SpringerLink
Log in

Therapie von Ejakulationsstörungen

  • Chapter
Pharmakotherapie in der Urologie

  • 61 Accesses

Zusammenfassung

Eine physiologische männliche Sexualfunktion bedarf der zeitlichen Koordinierung von Erektion, Orgasmus und Ejakulation. Obwohl Ejakulationsstörungen in der andrologischen Sprechstunde zumeist eine untergeordnete Rolle spielen und nur etwa 7% aller Männer mit Fertilitätsproblemen unter einer ejakulatorischen Dysfunktion leiden [34], scheinen zahlreiche epidemiologische Studien der jüngsten Vergangenheit zu belegen, daß die Ejakulatio praecox eine Praevalenz zwischen 4–75% in der männlichen Bevölkerung hat. [29, 41, 44]

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Log in via an institution
Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 54.99
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

Literatur

  1. Althof SE, Levine SB, Corty EW, Risen CB, Stern EB, Kurit DM (1995) A double — blind crossover trial of clomipramine for rapid ejaculation in 15 couples. J Clin Psych 56: 402–407

    CAS  Google Scholar 

  2. American Psychiatric Association (1994) Diagnostic and statistical manual of mental disorders. 4th ed. Washington DC: American Psychiatric Association. p 509–511

    Google Scholar 

  3. Annon J, Robinson C (1978) The use of vicarious learning in the treatment of sexual concerns. In: LoPiccolo J, LoPiccolo L (eds) Handbook of Sex Therapy. Plenum, New York, p 35–36

    Chapter  Google Scholar 

  4. Annon J (1987) Einfache Verhaltenstherapie bei sexuellen Problemen. In: Swanson J, Forrest K (Hrsg.) Die Sexualität des Mannes. Deutscher Ärzte Verlag, S 250–271

    Google Scholar 

  5. Balbay MD, Yildiz M, Salvarci A, Ozsan O, Ozbek E (1998) Treatment of premature ejaculation with sertralin. Int Urol Nephrol 30(1): 81–83

    Article  PubMed  CAS  Google Scholar 

  6. Bennett D (1961) Treatment of ejaculatio praecox with monoamino — oxidase inhibitors (letter). Lancet II: 1309

    Article  Google Scholar 

  7. Biri H, Isen K, Sinik Z, Onaran M, Kupeli B, Bozkirli I (1998) Sertraline in the treatment of premature ejaculation: a double — blind placebo controlled study. Int Urol Nephrol 30(5): 611–615

    Article  PubMed  CAS  Google Scholar 

  8. Blockmans D, Steeno O (1988) Physostigmine as a treatment for anejaculation with paraplegic men. Andrologia 20(4): 311–313

    Article  PubMed  CAS  Google Scholar 

  9. Boneff AN (1971) Topical treatment of chronic prostatitis and premature ejaculation. Int Urol Nephrol 4: 183–186

    Article  Google Scholar 

  10. Brackett NL (1999) Semen retrieval by penile vibratory stimulation in men with spinal cord injury. Hum Reprod Update 5(3): 216–222

    Article  PubMed  CAS  Google Scholar 

  11. Buffum J (1982) Pharmacosexology: The effects of drugs on sexual function: a review. J Psych Drugs 14: 5–44

    Article  CAS  Google Scholar 

  12. Cavallini G (1995) Alpha-1 blockade pharmacotherapy in primitive psychogenic premature ejaculation resistant to psychotherapy. Eur Urol 28(2): 126–130

    PubMed  CAS  Google Scholar 

  13. Chung PH,Yeko TR,Mayer JC,Sanford EJ,Maroulis GB (1995) Assisted fertility using electroejaculation in men with spinal cord injury- a review of literature. Fertil Steril 64(1): 1–9

    PubMed  CAS  Google Scholar 

  14. Colpi GM, Fanciullacci F, Beretta G, Negri L, Zanollo A (1986) Evoked sacral potentials in subjects with true premature ejaculation. Andrologia 18: 583–586

    Article  PubMed  CAS  Google Scholar 

  15. Cooper AG, Magnus RV (1984) A clinical trial of the beta blocker propranolol in premature ejaculation. J Psychosom Res 28: 331–336

    Article  PubMed  CAS  Google Scholar 

  16. Damrau F (1963) Premature ejaculation: Use of ethyl aminobenzoate to prolong coitus. J Urol 89: 936–938

    PubMed  CAS  Google Scholar 

  17. DeAmicis LA, Goldberg DC, LoPiccolo J, Friedman J, Davies L (1985) Clinical follow-up of couples treated for sexual dysfunction. Arch Sexual Behav 14: 467–489

    Article  CAS  Google Scholar 

  18. Denil J, Jonas U (1993) The management of disturbances of sperm transport. Eur Urol Update Series 2(11): 82–87

    Google Scholar 

  19. Denil J, Kupker W, Al-Hasani S, Schill T, Kuczyk MA, Jonas U, Diedrich K (1996) Successful combination of transrectal electroejaculation and intracytoplasmic sperm injection in the treatment of anejaculation. Hum Reprod 11(6): 1247–1249

    Article  PubMed  CAS  Google Scholar 

  20. Eaton H (1973) Clomipramine (Anafranil) in the treatment of pemature ejaculation. J Int Med Res 1: 432–434

    Google Scholar 

  21. Fahmy I, Kamal A, Metwali M, Rhodes C, Mansour R, Serour G, Aboulghar M (1999) Vigorous prostatic massage:a simple method to retrieve spermatozoa for intracytoplasmic sperm injection in psychogenic anejaculation:case report. Hum Reprod 14(8): 2050–2053

    Article  PubMed  CAS  Google Scholar 

  22. Fanciullacci F, Colpi GM, Beretta G, Zanollo A (1988). Cortical evoked potentials in subjects with true premature ejaculation. Andrologia 20:326–330

    Article  PubMed  CAS  Google Scholar 

  23. Fein RL (1990) Intracavernous medication for treatment of premature ejaculation. Urology 35 (4): 301–303

    Article  PubMed  CAS  Google Scholar 

  24. Gilja I, Parazajder J, Radej M, Cvitkovic P, Kovacic M (1994) Retrograde ejaculation and loss of emission:possibilities of conservative treatment. Eur Urol 25(3): 226–228

    PubMed  CAS  Google Scholar 

  25. Girgis SM, El-Haggen S, El-Hermouzy SA (1982) A double — blind trial of clomipramine in premature ejaculation. Andrologia 29: 364–368

    Google Scholar 

  26. Godpodinoff ML (1989) Premature Ejaculation:Clinical subgroups and etiology. J Sex Marital Ther 15: 1130–1134

    Article  Google Scholar 

  27. Goodman RE (1980) An assessment of clomipramine (Anafranil) in the treatment of premature ejaculation. J Int Med Res 8(S3): 53–59

    PubMed  Google Scholar 

  28. Graziottin A (1995) Prozac in the treatment of premature ejaculation. J Urol 83 (Suppl. 1): 474 A

    Google Scholar 

  29. Grenier G, Byers ES. (1997) The relationships among ejaculatory control, ejaculatory latency, and attempts to prolong heterosexual intercourse. Arch Sexual Behav 26: 27–47

    Article  CAS  Google Scholar 

  30. Haensel SM, Rowland DL, Kallan KT (1996) Clomipramine and sexual function in men with premature ejaculation and controls. J Urol 156(4): 1310–1315

    Article  PubMed  CAS  Google Scholar 

  31. Haensel SM, Klem TM, Hop WC, Slob AK (1998) Fluoxetine and premature ejaculation : a double — blind, placebo — controlled study. J Clin Psychpharmacol 18 (1): 72–77

    Article  CAS  Google Scholar 

  32. Hammer PM, Bain J (1986) Ejaculatory incompetence and infertility. Fertil Steril 45(3): 384–387

    Google Scholar 

  33. Hanel MJ (1998) Ejaculatio praecox. Therapiemanual. Enke, Stuttgart, S 8–9

    Google Scholar 

  34. Hargreave T, Pryor J, Jequier A, Crich J. (1983) Erectile and ejaculatory problems in infertility. In: Hargreave T (ed) Male Infertility. Springer, Berlin Heidelberg New York Tokyo, p 246–260

    Chapter  Google Scholar 

  35. Hawton K, Catalan J, Martin P, Fagg J (1986) Long — term outcome of sex therapy. Behav Res Ther 24: 665–675

    Article  PubMed  CAS  Google Scholar 

  36. Kara H, Aydin S, Agargun Y, Odabas O, Yilmiz Y (1996) The efficacy of fluoxetine in the treatment of premature ejaculation: a double-blind placebo controlled study. J Urol 156: 1631–1632

    Article  PubMed  CAS  Google Scholar 

  37. Keitner GI, Selub S (1983) Spontaneous ejaculation and neuroleptics. J Clin Psychopharmacol 3: 34–36

    Article  PubMed  CAS  Google Scholar 

  38. Kim SC, Seo KK (1998) Efficacy and safety of fluoxetine, sertraline and clomipramine in patients with premature ejaculation : a doupble — blind, placebo controlled study. J Urol 159(2): 425–427

    Article  PubMed  CAS  Google Scholar 

  39. Kim SW, Paick JS (1999) Short-term analysis of the effects of as needed use of sertraline at 5PM for the treatment of premature ejaculation. Urology 54(3):5 44–547

    Google Scholar 

  40. King J (1975) Impotence after fractures of the pelvis. J Bone Joint Surg 57: 1107–1118

    PubMed  CAS  Google Scholar 

  41. Kinsey AC, Pomeroy BW, Martin CE (1948) Sexual behaviour in the human male. Philadelphia, Saunders

    Google Scholar 

  42. Landau B, Benjamin D, Pinkhas T (1979) Ejaculation praecox and suprious polycythemia. JAMA 241: 1791–1792

    Article  PubMed  CAS  Google Scholar 

  43. La Pera G, Nicastro A (1996) A new treatment for premature ejaculation: the rehabilitation of the pelvic floor. J Sex Marital Ther 22(1): 22–26

    Article  PubMed  Google Scholar 

  44. Laumann EO, Gagnon JH, Michael RT, Michaels S (1994) The social organization of sexuality: Sexual practices in the United States. Chicago, University of Chicago Press

    Google Scholar 

  45. Ludovico GM, Corvasce A, Pagliarulo G, Cirillo-Marucco E, Marano A, Pagliarulo A (1996) Paroxetine in the treatment of premature ejaculation Br J Urol 77: 881–882

    Article  PubMed  CAS  Google Scholar 

  46. Masters WH, Johnson VE (1970). Human Sexual Response. Boston, Little, Brown

    Google Scholar 

  47. Matitiahu B, Keresteci AG, Koren G (1995) Efficacy of Prilocaine-Lidocaine cream in the treatment of premature ejaculation. J Urol 154: 1360–1361

    Article  Google Scholar 

  48. May AG, DeWeese JA, Rob CG (1969) Changes in sexual function following operation in the abnormal aorta. Surgery 65: 41–52

    PubMed  CAS  Google Scholar 

  49. Mc Mahon CG (1998) Treatment of premature ejaculation with sertraline hydrochloride. Int J Impot Res 10(3): 181–184

    Article  CAS  Google Scholar 

  50. McMahon CG (1998) Treatment of premature ejaculation with sertraline hydrochloride: a single-blind placebo controlled crossover study. J Urol 159(6): 1935–1938

    Article  PubMed  CAS  Google Scholar 

  51. McMahon CG, Tourna K (1999) Treatment of premature ejaculation with paroxetine hydrochloride. Int J Impot Res 11(5): 241–245

    Article  PubMed  CAS  Google Scholar 

  52. McMahon CG, Tourna K (1999) Treatment of premature ejaculation with paroxetine hydrochloride as needed: 2 single-blind placebo controlled crossover studies. J Urol 161(6): 1826–1830

    Article  PubMed  CAS  Google Scholar 

  53. Mendels J, Camera A, Silkes C (1995) Sertraline treatment for premature ejaculation. J Clin Psychopharmacol 15: 341–346

    Article  PubMed  CAS  Google Scholar 

  54. Narayan P, Lange P, Fraley E (1982) Ejaculation and fertility after extended retroperitoneal lymp node dissection for testicular cancer. J Urol 127: 69–72

    Google Scholar 

  55. Nikolettos N, Al-Hasani S, Baukloh V et al. (1999) The outcome of intracytoplasmic sperm injection in patients with retrograde ejaculation. Hum Reprod 14(9): 2293–2296

    Article  PubMed  CAS  Google Scholar 

  56. Ochsenkuhn R, Kamischke A, Nieschlag E (1999) Imipramine for successful treatment of retrograde ejaculation caused by retroperitoneal surgery. Int J Androl 22(3): 173–177

    Article  PubMed  CAS  Google Scholar 

  57. Petit J, Olivier F, Callenaere C, Carnier B (1994) The treatment of sterility due to retrograde ejaculation, using implantation of a pericervical sphincter prosthesis. Apropos of a case. Prog Urol 4(3): 423–425

    PubMed  CAS  Google Scholar 

  58. Pollack MH, Reiter S, Hammerness P (1992) Genitourinary and sexual adverse effects of psychotropic medication. Int J Psychiatry Med 22: 305–327

    PubMed  CAS  Google Scholar 

  59. Romero AD, Rebello SF (1994) The selective neurotomy of the dorsal nerve of penis: A new approach in the treatment of true premature ejaculation. Int J Impot Res 6 (Suppl. 1): D167

    Google Scholar 

  60. Saito K, Kinoshita Y, Yumura Y, Iwasaki A, Hosaka M (1998) Successful pregnancy with sperm retrieval from the bladder after the introduction of a low-electrolyte solution for retrograde ejaculation. Fertil Steril 69 (6): 1149–1151

    Article  PubMed  CAS  Google Scholar 

  61. Segraves RT (1987) Treatment of premature ejaculation with Lorazepam. Am J Psychiatry 144: 1240

    PubMed  CAS  Google Scholar 

  62. Segraves RT, Saran A, Segraves K, Maguire E (1993) Clomipramine versus placebo in the treatment of premature ejaculation: a pilot study. J Sex Marital Ther 19: 198–200

    Article  PubMed  CAS  Google Scholar 

  63. Shapiro B (1943) Premature ejaculation: A review of 1130 cases. J Urol 50: 374–379

    Google Scholar 

  64. St Lawrence JS, Madakasira S (1992) Evaluation and treatment of premature ejaculation:A critical review. Int J Psychiatry Med 22: 77–97

    Article  PubMed  CAS  Google Scholar 

  65. Strassberg DS, Mahoney JM, Schaugaard M, Hale VE (1990). The role of anxiety in premature ejaculation: A psychophysiological model. Arch Sex Behav 19: 251–257

    Article  PubMed  CAS  Google Scholar 

  66. Strassberg DS, de Gouveia Brazo CA, Rowland DL, Tan P, Slob AK (1999) Clomipramine in the treatment of rapid (premature) ejaculation. J Sex Marital Ther 25 (2): 89–101

    Article  PubMed  CAS  Google Scholar 

  67. Waldinger MD, Hengeveld MW, Zwinderman AH (1994) Paroxetine treatment of premature ejaculation: a double — blind, randomized, placebo — controlled study. Am J Psychiatry 151: 1377–1379

    PubMed  CAS  Google Scholar 

  68. Waldinger MD, Hengeveld MW, Zwinderman AH (1997) Ejaculation-retarding properties of paroxetine in patients with primary premature ejaculation: a double-blind, randomized, dose-response study. Br J Urol 79(4): 592–595

    Article  PubMed  CAS  Google Scholar 

  69. Witt MA, Grantmyre JE (1993) Ejaculatory failure. World J Urol 11(2): 89–95

    Article  PubMed  CAS  Google Scholar 

  70. Yells DP, Prendergast MA, Hendricks SE, Nakamura M (1994). Fluoxetine-induced inhibition of male rat copulatory behavior: modification by lesions of the nucleus paragigantocellularis. Pharmacol Biochem Behav 49: 121–127

    Article  PubMed  CAS  Google Scholar 

  71. Yeoman RR, Sonksen J, Gibson SV, Rizk BM, Abee CR (1998) Penile vibratory stimulation yields increased spermatozoa and accessory gland production compared with rectal electroejaculation in a neurologically intact primate (Saimiri boliviensis). Hum Reprod 13(9): 2527–31

    Article  PubMed  CAS  Google Scholar 

  72. Yilmaz U, Tatlisen A, Turan H, Arman F, Ekmekcioglu O (1999) The effects of fluoxetine on several neurophysiological variables in patients with premature ejaculation. J Urol 161 (1): 107–111

    Article  PubMed  CAS  Google Scholar 

Download references

Authors
  1. S. Machtens
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. A. J. Becker
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. M. A. Kuczyk
    View author publications

    You can also search for this author in PubMed Google Scholar

Editor information

Editors and Affiliations

  1. Urologische Klinik und Poliklinik, Medizinische Hochschule Hannover, Carl-Neuberg-Str. 1, 30625, Hannover, Deutschland

    Michael C. Truss , Christian G. Stief , Stefan Machtens  & Udo Jonas (Direktor), ,  &  (Direktor)

  2. Zentrum Anästhesiologie, Medizinische Hochschule Hannover, Carl-Neuberg-Str. 1, 30625, Hannover, Deutschland

    Till Wagner

Rights and permissions

Reprints and permissions

Copyright information

© 2002 Springer-Verlag Berlin Heidelberg

About this chapter

Cite this chapter

Machtens, S., Becker, A.J., Kuczyk, M.A. (2002). Therapie von Ejakulationsstörungen. In: Truss, M.C., Stief, C.G., Machtens, S., Jonas, U., Wagner, T. (eds) Pharmakotherapie in der Urologie. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-662-09273-6_18

Download citation

  • DOI: https://doi.org/10.1007/978-3-662-09273-6_18

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-540-41519-0

  • Online ISBN: 978-3-662-09273-6

  • eBook Packages: Springer Book Archive

Publish with us

Policies and ethics

Search

Navigation