Abstract
In recent years, immobilized peptides synthesized on activated cellulose membranes (SPOT synthesis, Frank 1992) have become an important tool in the study of protein-protein interactions and numerous other aspects of molecular recognition (reviewed in Reineke et al. 2001). A broad range of applications has already been described and the rising interest in proteomics is bound to rely on the enormous potential of the (automated) method. When adapted to high-throughput screening, SPOTs, i.e. peptide arrays, will become an invaluable tool in pharmacogenomics and drug discovery.
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© 2002 Springer-Verlag Berlin Heidelberg
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Bräuning, R., Mahler, M., Hügle-Dörr, B., Blüthner, M., Koch, J., Petersen, G. (2002). Immobilized Peptides to Study Protein-Protein Interactions — Potential and Pitfalls. In: Koch, J., Mahler, M. (eds) Peptide Arrays on Membrane Supports. Springer Lab Manuals. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-662-09229-3_11
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DOI: https://doi.org/10.1007/978-3-662-09229-3_11
Publisher Name: Springer, Berlin, Heidelberg
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