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Pädiatrie pp 381-391 | Cite as

Mitochondriopathien

  • J. Smeitink
  • U. Wendel

Zusammenfassung

Hierunter fallen die Krankheitsbilder der oxidativ-metabolischen Zytopathien, denen Störungen der Pyruvatoxidation, des Zitratzyklus oder des in der inneren Mitochondrienmembran lokalisierten Systems der oxidativen Phosphorylierung (OXPHOS) zugrunde liegen. Im allgemeinen ist bei diesen Krankheiten intermittierend oder chronisch der Laktatspiegel im Blut und/oder Liquor cerebrospinalis infolge gestörter Substratoxidation erhöht.

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Copyright information

© Springer-Verlag Berlin Heidelberg 2003

Authors and Affiliations

  • J. Smeitink
  • U. Wendel

There are no affiliations available

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