Sulfonylureas: Pharmacokinetics in Animal Experiments

  • A. Hasselblatt
Part of the Handbook of Experimental Pharmacology book series (HEP, volume 119)

Abstract

This chapter reviews the pharmacokinetics of the sulfonylurea compounds in animals. This is a rather restricted area which has so far failed to attract significant research effort. As sulfonylureas were developed to be used in man, more attention has been dedicated to their behavior within the human body than to their fate in animals. Thus the data available from animals have not usually exceeded those required for the decision to be made to use these agents in man. In addition, it is likely that not all the relevant data have been made available to the public.

Keywords

Coumarin Biotransformation Phenobarbital Tolbutamide Probenecid 

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  • A. Hasselblatt

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