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Pathophysiology of Type 2 Diabetes Mellitus

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Oral Antidiabetics

Part of the book series: Handbook of Experimental Pharmacology ((HEP,volume 119))

Abstract

Non-insulin-dependent diabetes mellitus (NIDDM), also called type 2 diabetes mellitus, is a common metabolic disorder that afflicts 2%–5% of the adult population of most Western countries, with, however, wide international variation (King et al. 1993). Furthermore, NIDDM is often undiagnosed even in the Western countries (Hortulanus-Beck et al. 1990), and numerous data indicate that undiagnosed NIDDM is not a benign condition (Harris 1993). Certainly, NIDDM is a leading cause of disability and death in developed and developing nations (Songer 1992).

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Scheen, A.J., Lefèbvre, P.J. (1996). Pathophysiology of Type 2 Diabetes Mellitus. In: Kuhlmann, J., Puls, W. (eds) Oral Antidiabetics. Handbook of Experimental Pharmacology, vol 119. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-662-09127-2_2

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